Protein Alignment CG5776 and spas

DIOPT Version :10

• Sequence 1: NP_609585.1
• Gene: CG5776 / 34680
• FlyBaseID: FBgn0032450
• Length: 799
• Species: Drosophila melanogaster
• Sequence 2: NP_651206.3
• Gene: spas / 42846
• FlyBaseID: FBgn0039141
• Length: 758
• Species: Drosophila melanogaster
• Alignment Length: 556
• Identity: 145/556 - (26%)
• Similarity: 239/556 - (42%)
• Gaps: 138/556 - (24%)

  Fly   329 EERSQGHVQLIRINSGEVYSKFLGETEQKL--------GAIFERAYN-HYPHPTLLLI--EDVHN 382
            :|.::||.:|    :.|:|.|.:.|.|..:        |.:::||.. |....|.|.:  :.:|.
  Fly   247 DEENEGHKEL----AIELYRKGIKELEDGIAVDCWSGRGDVWDRAQRLHDKMQTNLSMARDRLHF 307

  Fly   383 LCPKQENSDLVKRVSLAFLSLLDQLSSPSQLKGSKTF--VLATSSQIDTLHPSIRRAGRLDNEVE 445
            |..::::..:.:      |||.::....:|.|..||.  :||..:. :.:...:|.:|.......
  Fly   308 LALREQDLQMQR------LSLKEKQKEEAQSKPQKTREPMLAGMTN-EPMKLRVRSSGYGPKATT 365

  Fly   446 LGAPSSQARLEIVRCLIKSVEHQLSDEEVEHVASITHGYVGADLANLVYAAMLQAQPNPLQMP-- 508
            ...|::..|                        .:|.|  .....||..|...|..|..|...
  Fly   366 SAQPTASGR------------------------KLTIG--SKRPVNLAVANKSQTLPRNLGSKTS 404

  Fly   509 ----HLQAALTRIKPSAMR---------------------------------------------- 523
                ..|.|.|...|.|:|
  Fly   405 VGAVQRQPAKTAATPPAVRRQFSSGRNTPPQRSRTPINNNGPSGSGASTPVVSVKGVEQKLVQLI 469

  Fly   524 --EVLIECPNVQWSDIGGQSELRLAMQQAIEWPLLHADKFQRLGIK-PPRGILMFGPPGCSKTMI 585
              |::.....|:|:||.||...:.|:|:.:..|.:..:.|  .|:: |.:|:|:|||||..||::
  Fly   470 LDEIVEGGAKVEWTDIAGQDVAKQALQEMVILPSVRPELF--TGLRAPAKGLLLFGPPGNGKTLL 532

  Fly   586 AKALATESKLNFLSIKGPELFSMWVGESERAVREVFRKARQVAPAIVFFDEIDAIGGERSEGDGS 650
            |:|:|||....||:|....|.|.:||:.|:.||.:|..||.:.|:|:|.||:|::..||     |
  Fly   533 ARAVATECSATFLNISAASLTSKYVGDGEKLVRALFAVARHMQPSIIFIDEVDSLLSER-----S 592

  Fly   651 SSGSSVKERVLTQLLTELDGVEAL---QNVTIVAATNRPDMIDKALLRPGRIDRILYVGLPQCEA 712
            ||......|:.|:.|.|.||:...   ..:.::||||||..:|:|.||  |..:.:||.||. |.
  Fly   593 SSEHEASRRLKTEFLVEFDGLPGNPDGDRIVVLAATNRPQELDEAALR--RFTKRVYVSLPD-EQ 654

  Fly   713 RREILKIKL---RAMPISNDVDMEKLVQLTEGYSGAEIQAVCHEAALRALEQSFEAEDVKW---- 770
            .||:|..:|   :..|:..:. :.:|.::|:||||:::.|:..:|||..:.: ...|.||.
  Fly   655 TRELLLNRLLQKQGSPLDTEA-LRRLAKITDGYSGSDLTALAKDAALEPIRE-LNVEQVKCLDIS 717

  Fly   771 -------TDFEHALKAVPPRTSPELLKLYE----DY 795
                   .||..:||.:....:|:.|..||    ||
  Fly   718 AMRAITEQDFHSSLKRIRRSVAPQSLNSYEKWSQDY 753

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5776	NP_609585.1	CDC48	183..797	CDD:273521	145/556 (26%)
spas	NP_651206.3	MIT_spastin	230..308	CDD:239142	16/64 (25%)
		RecA-like_spastin	484..648	CDD:410932	65/172 (38%)
		AAA_lid_3	676..727	CDD:465537	13/51 (25%)
		Vps4_C	<722..754	CDD:462762	10/32 (31%)