Protein Alignment CG5776 and CG14183

DIOPT Version :10

• Sequence 1: NP_609585.1
• Gene: CG5776 / 34680
• FlyBaseID: FBgn0032450
• Length: 799
• Species: Drosophila melanogaster
• Sequence 2: NP_649172.3
• Gene: CG14183 / 40192
• FlyBaseID: FBgn0036931
• Length: 872
• Species: Drosophila melanogaster
• Alignment Length: 877
• Identity: 153/877 - (17%)
• Similarity: 319/877 - (36%)
• Gaps: 212/877 - (24%)

  Fly    63 LQQRNFEVESLKDLPTKYANMLVFVSEGAMQLAQ-------LHIGQHVVLEAPSTAEQ--PLVRI 118
            :....|:|:       |.|.:.|.|.....||.|       |.:.:::.::....|.:  |...:
  Fly    60 IYHNTFQVQ-------KRALVRVLVENATQQLMQLKEELKDLEMSEYIYIDKALIARKLTPRDLV 117

  Fly   119 VWPTSEQFLTTVFVSEGDFKLHCTQLRGKLLKISALHPSRLTAAASISLKHVNTTETSLKSVQ-- 181
            || .|.|||                .|..|...:.:..:||         ::|..|...|:.|
  Fly   118 VW-RSPQFL----------------YRRPLDIQNIIADNRL---------YMNDEEKEEKAAQDW 156

  Fly   182 --LQDAIALLK-RDMVNRV-FYKDSL---------IHM-NFFNKSLTFRLERWQS-TVEEALAGL 231
              :.:|:.|:: .:...|. .||.::         :|. ...|...||:.::..| .|:..:  .
  Fly   157 VPISEAVKLIQAHERARRARVYKSNIKYDKKKFLKVHQRKKINYKFTFKPDQAMSIPVKRTI--F 219

  Fly   232 SLDSKPLQFIQV----TNVTKLHLITDDANQQEE-----EQKISHRITKCQIGGLDRQLQLVEES 287
            |.|     |::.    .|:.|...:.|.|...||     :...:.:|..|..|...|::..:.:.
  Fly   220 SAD-----FLKADESCENLIKKDDVADTAIDDEEALSAIQNNAACKIQSCWRGYKTRKIVKIRKR 279

  Fly   288 MEYAL----GFRTLPAGLRVSRGLL-LYGATGCGKSMVLEAMCAVAEERSQGHVQLIRINSGEVY 347
            .:..|    ..|.|....:.:..:: :|......|.:..:.:..:.:||:    :|::..|
  Fly   280 FKEELYGMKKIRKLKRPNQTANSIMEMYKNEMLKKKLDEDFINLINDERT----RLLQFRS---- 336

  Fly   348 SKFLGETEQKLGAIFERAY----NHYPHP------TLLLIEDVHNLCPKQENSDLVKR-VSLAFL 401
            ...:.:....:.|.|:..|    |.:|:|      |:|::.| ..:.|.:....|.|: :|.|.|
  Fly   337 PWMMEDISDHIRAWFKEFYDATGNFHPYPDPVKQGTVLVVID-ETMTPMEFQESLGKKPLSKAEL 400

  Fly   402 -SLLDQLSSPSQLKGSKTFVLATSSQIDTLHPSIRRAGRLDNEVELGAPSSQARLE--------- 456
             .|.|:.....:.|..|...|.....  .....:|.||.:|...||.|..:...:|
  Fly   401 KKLRDKEKKEKRKKKEKLKQLKMKEA--KRRKKLRDAGVIDIGYELTASKAIENIEETMKKYSKD 463

  Fly   457 ---IVRCLIKS---VEHQLSDEEVEHVASITHGYVGADLANLVYAAMLQA---------QPNPLQ 506
               :...|.|:   ::..:::|::..:.....|.|. :...:.|..:.:|         :...::
  Fly   464 WRNVDEYLNKNHDPIKEWVTEEQLAKIHQEVRGLVD-EYMRVEYELLREALAKDNDEKYKALKVK 527

  Fly   507 MPHLQAALTRIKPSAMR-EVLIECPNVQWSDIG-------------------------------- 538
            .|..:....:.||..|. :..:|....:..|.|
  Fly   528 YPKKKKEKRKKKPKDMTGDRTLESLYNELKDAGIIEEIGHRDFDEFITDFNFVADDTRDEDGLTT 592

  Fly   539 ---GQSELRLAMQQAIEWPLLHADKFQRLGIKPPRGILMFGPPGCSKTMIAKALATESKLNFLSI 600
               .:.::::.:|::    :|...:|.   :..|:.:|:.||....|.::.:.:|:|....|:::
  Fly   593 LGPAKGDIKMVIQES----MLGMGEFD---VPKPKSLLLIGPLNSGKRLLCEIIASELDAVFMNL 650

  Fly   601 KGPELFSMWVGESERAVREVFRKARQVAPAIVFFDEI-----DAIGGERSEGDGSSSGSSVKERV 660
             .||....:..:.:..:..:.:.|:...|.|::.:|.     ..:..|..|.:....|:|:..::
  Fly   651 -SPENTYKYAKDLKYFLHVILKVAKAFQPTIMYIEEAHRLFWKKVPPEAVEINPRLLGTSLASKI 714

  Fly   661 LTQLLTELDGVEALQNVTIVAATNRPDMIDKALLRPGRIDRILYVGLPQCEARREILKIKLRAMP 725
            |..|       :....:.:|..:|.|...:..:.|  ...::|.:  |:|:.....| :.|..|.
  Fly   715 LKPL-------KKNDKIVLVGTSNMPWAANGGIKR--AFQKVLLI--PKCDYGTSFL-LWLELMT 767

  Fly   726 ISNDVDMEK-----LVQLTEGYSGAEIQAVCHEAALRALEQSFEAEDVKWTDF-EHAL-KAVPPR 783
            .:...||::     |.::.:.|:..:|.....|......:...:.|.:...:| |:.| |..||.
  Fly   768 ENAPDDMKEYAYSALARVLQAYNSGDIDDNVKETLNIDRKMRLKNEALDPNEFLEYFLSKNEPPI 832

  Fly   784 TSPE----------------LLKLYEDYLKRK 799
            ..|:                |.||.:.|:.:|
  Fly   833 FPPDEKIMDKFNKWFGSSNKLEKLRKSYMAQK 864

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5776	NP_609585.1	CDC48	183..797	CDD:273521	126/740 (17%)
CG14183	NP_649172.3	Adgb_C_mid-like	<201..>278	CDD:412094	17/83 (20%)
		globin helix H	201..232	CDD:412094	7/37 (19%)
		IQCD	247..278	CDD:467745	6/30 (20%)
		IQ motif	259..277	CDD:412094	4/17 (24%)
		P-loop containing Nucleoside Triphosphate Hydrolases	617..750	CDD:476819	25/142 (18%)