Protein Alignment CG5776 and FIGNL2

DIOPT Version :10

• Sequence 1: NP_609585.1
• Gene: CG5776 / 34680
• FlyBaseID: FBgn0032450
• Length: 799
• Species: Drosophila melanogaster
• Sequence 2: XP_016874787.1
• Gene: FIGNL2 / 401720
• HGNCID: 13287
• Length: 767
• Species: Homo sapiens
• Alignment Length: 292
• Identity: 90/292 - (30%)
• Similarity: 152/292 - (52%)
• Gaps: 25/292 - (8%)

  Fly   517 IKPSAMREV---LIEC-PNVQWSDIGGQSELRLAMQQAIEWPLLHADKFQRLGIKPPRGILMFGP 577
            :.|.|:..|   :::| |.|||:|:.||..|:.|:::.:.||||....:.. .::|||.:|:|||
Human   484 VDPGALELVTSKMVDCGPPVQWADVAGQGALKAALEEELVWPLLRPPAYPG-SLRPPRTVLLFGP 547

  Fly   578 PGCSKTMIAKALATESKLNFLSIKGPELFSMWVGESERAVREVFRKARQVAPAIVFFDEIDAIGG 642
            .|..|.::.:.|||:.....|.::|..|.:....|..|.::..|..||...|:::...|::|:..
Human   548 RGAGKALLGRCLATQLGATLLRLRGATLAAPGAAEGARLLQAAFAAARCRPPSVLLISELEALLP 612

  Fly   643 ERSEGDGSSSGSSVKERVLTQLLTELDG--VEALQNVTIVAATNRPDMIDKALLRPGRIDRILYV 705
            .|.  ||:::|.:::    ..||..|||  ......|.:|..|:||..:|:|..|  |.....||
Human   613 ARD--DGAAAGGALQ----VPLLACLDGGCGAGADGVLVVGTTSRPAALDEATRR--RFSLRFYV 669

  Fly   706 GLPQCEARREILKIKLRAMPIS-NDVDMEKLVQLTEGYSGAEIQAVCHEAA----LRALEQSFEA 765
            .||...||.:||:..|.....: ::.::..|||.|:|:||.|:..:|.:||    |..|::
Human   670 ALPDSPARGQILQRALAQQGCALSERELAALVQGTQGFSGGELGQLCQQAAAGAGLPGLQR---- 730

  Fly   766 EDVKWTDFEHALKAVPPRTSPELLKLYEDYLK 797
             .:.:.|.|.||..|.||.|.:.|..:.::.|
Human   731 -PLSYKDLEAALAKVGPRASAKELDSFVEWDK 761

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5776	NP_609585.1	CDC48	183..797	CDD:273521	89/290 (31%)
FIGNL2	XP_016874787.1	RecA-like_fidgetin	507..669	CDD:410931	50/170 (29%)
		HflB	<643..>720	CDD:440233	27/78 (35%)