Protein Alignment CG5776 and DRC11L

DIOPT Version :10

• Sequence 1: NP_609585.1
• Gene: CG5776 / 34680
• FlyBaseID: FBgn0032450
• Length: 799
• Species: Drosophila melanogaster
• Sequence 2: NP_001291348.1
• Gene: DRC11L / 392843
• HGNCID: 22831
• Length: 818
• Species: Homo sapiens
• Alignment Length: 549
• Identity: 107/549 - (19%)
• Similarity: 203/549 - (36%)
• Gaps: 142/549 - (25%)

  Fly   342 NSGEVYSKFLGETEQKLGAIFERAYNHYPHPTLLLIEDVHNLCPKQENS---------------D 391
            :||..||.|..:|.:::....|             ::...|...:||.|               :
Human   321 SSGGSYSIFADKTPEQVRMELE-------------MQMQENRKKEQEKSKEKGKDEKEKKKGKEE 372

  Fly   392 LVKRVSL-AFLSLLDQLSSPSQLKGSKTFVLATSSQIDTLHPS-------IRRAGRLDNEVELGA 448
            ..|:..: |.|.:|.....|....|.:.::....::.:::|||       :|...|.:.|:|:..
Human   373 KAKKGEVDAVLQVLPSKCIPMICAGHEEYLNTWKNRCESIHPSQNYDSETLREEKRKEVELEIRI 437

  Fly   449 PSSQARLEIVRCLIKSVEHQ------------------------LSDEEVEHVASITHGYVGADL 489
            ...:...:.:|.|..:|:.:                        .||..||.:           .
Human   438 QVDELMRQELRKLRLAVDKEEERPLRAPKKTPGKKTGKKKEKDLTSDRSVESL-----------Y 491

  Fly   490 ANLVYAAMLQAQPNPL------QMPHLQAALTRIKPSAMREVLIECPNVQWSDIGGQSELRLAMQ 548
            ..||.:.:|:...:..      ...:|.:.|:.:|...|..:.....||....:     |||..
Human   492 EELVISGLLRKSESVALKDYIGDFLYLGSTLSLVKKLPMPSLFDIRQNVALYAV-----LRLGS- 550

  Fly   549 QAIEWPLLHADKFQRLGIKPP--RGILMFGPPGCSKTMIAKALATESKLNFLSIKGPELFSMWVG 611
                 |.:|        |..|  |.||:.||.|..|.|:.||:.||:..|...:....|...:.|
Human   551 -----PDIH--------IMAPLIRSILLVGPSGMGKKMLVKAVCTETGANLFDLSPENLLGKYPG 602

  Fly   612 E--SERAVREVFRKARQVAPAIVFFDEIDAIGGERSEGDGSSSGSSVKERVLT---QLLTELDGV 671
            .  ::..|..||:.||.:.|::::....:....:::..:.........::.||   :|||..|
Human   603 RNGAQMMVHIVFKVARLLQPSVIWIGNAEKNFYKKTPKEDKEMDPKRIKKDLTKALRLLTPGD-- 665

  Fly   672 EALQNVTIVAATNRPDMID-KALLRPGRIDRILYVGLPQCEARREILK--IKLRAMPISNDVDME 733
                .|.::..|:||.:.: :.|.|.  .:|||::..|...:|..:.|  |:.|.:..:..:|:.
Human   666 ----RVMLIGTTSRPQLAEMRGLCRV--YERILFMPRPDYASRYVLWKRMIEARGIQPTQHLDIS 724

  Fly   734 KLVQLTEGYSGAE----IQAVCHE-----------------AALRALEQSFEAEDVKWTDF---- 773
            .|.::::||:...    ||:|..|                 ..|..|:..:..|:....|:
Human   725 ALAKVSDGYTPGHILQAIQSVLSERRFLQLSKRPLVASEFLGQLVKLDPVYREEEESLKDWYFKT 789

  Fly   774 ---EHALKAVPPRTSPELLKLYEDYLKRK 799
               :.::|....:...|..||.::..|||
Human   790 PLGKKSMKHRMDQLEAEEAKLDKEKKKRK 818

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5776	NP_609585.1	CDC48	183..797	CDD:273521	104/545 (19%)
DRC11L	NP_001291348.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	344..377		5/32 (16%)
		SpoVK	411..744	CDD:440232	76/370 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	458..482		0/23 (0%)
		P-loop containing Nucleoside Triphosphate Hydrolases	535..694	CDD:476819	45/185 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	795..818		5/22 (23%)