Protein Alignment CG5776 and Nvl

DIOPT Version :10

• Sequence 1: NP_609585.1
• Gene: CG5776 / 34680
• FlyBaseID: FBgn0032450
• Length: 799
• Species: Drosophila melanogaster
• Sequence 2: NP_001099450.1
• Gene: Nvl / 289323
• RGDID: 1311270
• Length: 855
• Species: Rattus norvegicus
• Alignment Length: 765
• Identity: 235/765 - (30%)
• Similarity: 373/765 - (48%)
• Gaps: 182/765 - (23%)

  Fly   192 DMVNRVFYKD--SLIHMN-----FFNK------SLTFRLERWQSTVEEALAGLSLDSKPLQ---- 239
            |..|...|.|  |..|||     .:.|      |.|.:||:.:......|.....||.||:
  Rat   102 DDSNMEDYPDPQSANHMNSSLLSLYRKGNSDSVSTTPKLEQREDATSSPLLSSKTDSMPLKTPAR 166

  Fly   240 ------FIQVT-----NVTKLHLITDDANQQEEEQKISH-------------------------- 267
                  ||..|     ....|.|..|.:|.::::..|.:
  Rat   167 EPEGGWFIDKTPGGQKESLPLDLSDDQSNCKKQDPGIQNLKDSSLLESDKKRKSRAKGKGNKRKT 231

  Fly   268 --------------------RITKCQI--------GGLDRQLQLVEE---SMEYALGFRTLPAGL 301
                                :.|:.||        ||.|..|:.|.:   .|.:...::.|  |:
  Rat   232 EGLQEADGEIEAILQKRAKAKSTELQISSVKFEDVGGNDATLKEVCKMLIHMRHPEVYQHL--GV 294

  Fly   302 RVSRGLLLYGATGCGKSMVLEAMCAVAEERSQGHVQLIRINSGEVYSKFLGETEQKLGAIFERAY 366
            ...||:||:|..||||:::..|:....:      :.::::.:.|:.|...||:||||..:|::|.
  Rat   295 VPPRGVLLHGPPGCGKTLLAHAIAGELD------LPILKVAAPEIVSGVSGESEQKLRDLFDQAV 353

  Fly   367 NHYPHPTLLLIEDVHNLCPKQE--NSDLVKRVSLAFLSLLDQLSSPSQLKGSKTFVLATSSQIDT 429
            ::  .|.::.|:::..:.||:|  :.|:.:|:....|:.:|.|::.:..  ::..|:..:::.|:
  Rat   354 SN--APCIVFIDEIDAITPKREVASKDMERRIVAQLLTCMDDLNNVAAT--ARVLVVGATNRPDS 414

  Fly   430 LHPSIRRAGRLDNEVELGAPSSQARLEIVRCLIKSVEHQLSDE-EVEHVASITHGYVGADLANLV 493
            |.|::|||||.|.||.||.|...:|..|::.|.:.:  :|.:. ...|:|.:|.|:|||||..|.
  Rat   415 LDPALRRAGRFDREVCLGIPDEASRERILQTLCRKL--RLPETFNFSHLAHLTPGFVGADLMALC 477

  Fly   494 YAA---------------------------------MLQAQP------------------NPLQM 507
            ..|                                 .|.|:|                  :|:..
  Rat   478 REAAVCAVHRVLMRRQEQQRTEPETGGLPSDGEQGRSLGAEPPSETQDELQRLLGLLRDQDPISE 542

  Fly   508 PHLQ----------AALTRIKPSAMREVLIECPNVQWSDIGGQSELRLAMQQAIEWPLLHADKFQ 562
            ..:|          .||:.::|||.||..:..|||.|:|:|...::|..:..||..|:.:.::|:
  Rat   543 EQMQGLCLELNDFIVALSEVQPSAKREGFVTVPNVTWADVGALEDIREELTMAILAPVRNPEQFR 607

  Fly   563 RLGIKPPRGILMFGPPGCSKTMIAKALATESKLNFLSIKGPELFSMWVGESERAVREVFRKARQV 627
            .||:..|.|:|:.|||||.||::|||:|.||.|||:|:|||||.:|:|||||||||:||::|:..
  Rat   608 ALGLVAPAGVLLAGPPGCGKTLLAKAVANESGLNFISVKGPELLNMYVGESERAVRQVFQRAKNS 672

  Fly   628 APAIVFFDEIDAIGGERSEGDGSSSGSSVKERVLTQLLTELDGVEALQNVTIVAATNRPDMIDKA 692
            ||.::||||:||:...||:.:   :|:||  ||:.|||||:||:|..|.|.|:|||||||:||.|
  Rat   673 APCVIFFDEVDALCPRRSDRE---TGASV--RVVNQLLTEMDGLETRQQVFILAATNRPDIIDPA 732

  Fly   693 LLRPGRIDRILYVGLPQCEARREILKIKLR---AMPISNDVDMEKLV--QLTEGYSGAEIQAVCH 752
            :|||||:|:.|:||||....|..|||...:   ..|:..|||:|.:.  ...:.|:||::.|:..
  Rat   733 ILRPGRLDKTLFVGLPPPADRVAILKTITKNGTKPPLDEDVDLEAIANDHRCDCYTGADLSALVR 797

  Fly   753 EAALRALEQSFEAE---------DVKWTDFEHALKAVPPRTSPELLKLYE 793
            ||:|.||.|....:         .|....||.|.:.|.|..|.:..::||
  Rat   798 EASLCALRQEITGQKNGIGTAELTVSHKHFEEAFRKVKPSISVKDQRMYE 847

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5776	NP_609585.1	CDC48	183..797	CDD:273521	235/765 (31%)
Nvl	NP_001099450.1	Nucleolin_bd	2..71	CDD:465247
		CDC48	<255..855	CDD:273521	208/612 (34%)