Protein Alignment CG5776 and mac-1

DIOPT Version :10

• Sequence 1: NP_609585.1
• Gene: CG5776 / 34680
• FlyBaseID: FBgn0032450
• Length: 799
• Species: Drosophila melanogaster
• Sequence 2: NP_496814.1
• Gene: mac-1 / 174974
• WormBaseID: WBGene00003119
• Length: 813
• Species: Caenorhabditis elegans
• Alignment Length: 729
• Identity: 240/729 - (32%)
• Similarity: 370/729 - (50%)
• Gaps: 132/729 - (18%)

  Fly   161 AAASISLKHVNTTETSLKSVQLQDAIALLKRDMVNRVFYKDSLIHMNFFNK----SLTFRLERWQ 221
            |||:..:...:.:|....:.||:..|..||.:..|:..       :|.:.|    |......:.|
 Worm   113 AAAAKEVVLSDDSEDERAARQLEKQIESLKTNRANKTV-------LNLYTKKSAPSTPVSTPKNQ 170

  Fly   222 STVEEALAGLSLDSKPLQFIQVTNVTKLHLITDDANQQEEEQKISHRITKCQIGGLDRQ-LQLVE 285
            :|.:...|..:..:.|         ..|..::|..:.:|...|..|      |||.||| |::..
 Worm   171 ATKKPPGASAAPPALP---------RGLGAVSDTISPRESHVKFEH------IGGADRQFLEVCR 220

  Fly   286 ESM--EYALGFRTLPAGLRVSRGLLLYGATGCGKSMVLEAMCAVAEERSQGHVQLIRINSGEVYS 348
            .:|  :....|.||  |:...||.:::|..||||:|..:   |||.|.:   :.::::.:.|:.|
 Worm   221 LAMHLKRPKTFATL--GVDPPRGFIVHGPPGCGKTMFAQ---AVAGELA---IPMLQLAATELVS 277

  Fly   349 KFLGETEQKLGAIFERAYNHYPHPTLLLIEDVHNLCPKQENS--DLVKRVSLAFLSLLDQLSSPS 411
            ...||||:|:..:|:.|..:  .|.:|:::|:..:.|::|.:  ::.:||.....|.||:|..|.
 Worm   278 GVSGETEEKIRRLFDTAKQN--SPCILILDDIDAIAPRRETAQREMERRVVSQLCSSLDELVLPP 340

  Fly   412 Q---LKGSKTF---------------------VLATSSQIDTLHPSIRRAGRLDNEVELGAPSSQ 452
            :   ||...||                     |:.|:|:.|.:...:|||||.:||:.||.|...
 Worm   341 REKPLKDQLTFGDDGSVAIIGDSPTAAGAGVLVIGTTSRPDAVDGGLRRAGRFENEISLGIPDET 405

  Fly   453 ARLEIVRCLIKSVEHQLSDEEVEHVASITHGYVGADLANLV------------------------ 493
            ||.:|:..:.|  .:...|..::.:|.:|.|||||||..|:
 Worm   406 AREKILEKICK--VNLAGDVTLKQIAKLTPGYVGADLQALIREAAKVAIDRVFDTIVVKNEGHKN 468

  Fly   494 ------------YAAMLQAQPNPLQMPHL-----------QAALTRIKPSAMREVLIECPNVQWS 535
                        ..|.||...:|..:..|           :.||:.|:|:|.||.....|:|.|.
 Worm   469 LTVEQIKEELDRVLAWLQGDDDPSALSELNGGLQISFEDFERALSTIQPAAKREGFATVPDVSWD 533

  Fly   536 DIGGQSELRLAMQQAIEWPLLHADKFQRLGIK-PPRGILMFGPPGCSKTMIAKALATESKLNFLS 599
            |||...|:|..::.:|.:|:..||.|..|||. .|:|||:.|||||.||::|||:|.|:.:||:|
 Worm   534 DIGALVEVRKQLEWSILYPIKRADDFAALGIDCRPQGILLCGPPGCGKTLLAKAVANETGMNFIS 598

  Fly   600 IKGPELFSMWVGESERAVREVFRKARQVAPAIVFFDEIDAIGGERSEGDGSSSGSSVKERVLTQL 664
            :|||||.:|:|||||||||.||::||...|.::|||||||:..:||.|:  |||.:   |::.||
 Worm   599 VKGPELLNMYVGESERAVRTVFQRARDSQPCVIFFDEIDALVPKRSHGE--SSGGA---RLVNQL 658

  Fly   665 LTELDGVEALQNVTIVAATNRPDMIDKALLRPGRIDRILYVGLPQCEARREIL----KIKLRAMP 725
            |||:||||..|.|.::.||||||::|.|:|||||:|:||:|..|..|.|.:||    |...|.|
 Worm   659 LTEMDGVEGRQKVFLIGATNRPDIVDAAILRPGRLDKILFVDFPSVEDRVDILRKSTKNGTRPM- 722

  Fly   726 ISNDVDMEKLVQLTE--GYSGAEIQAVCHEAAL-----RALEQSFEAEDVKWTDFEHALKAVPPR 783
            :..|:|..::.||.|  |::||::.|:.||::|     |.||.....:.|....|..|...:.|.
 Worm   723 LGEDIDFHEIAQLPELAGFTGADLAALIHESSLLALQARVLENDESVKGVGMRHFREAASRIRPS 787

  Fly   784 TSPELLKLYEDYLK 797
            .:....|.||...|
 Worm   788 VTEADRKKYEHMKK 801

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5776	NP_609585.1	CDC48	183..797	CDD:273521	233/705 (33%)
mac-1	NP_496814.1	Nucleolin_bd	5..65	CDD:465247
		CDC48	<191..804	CDD:273521	222/635 (35%)