Protein Alignment CG5776 and cdc-48.3

DIOPT Version :10

• Sequence 1: NP_609585.1
• Gene: CG5776 / 34680
• FlyBaseID: FBgn0032450
• Length: 799
• Species: Drosophila melanogaster
• Sequence 2: NP_492211.1
• Gene: cdc-48.3 / 172586
• WormBaseID: WBGene00010562
• Length: 724
• Species: Caenorhabditis elegans
• Alignment Length: 816
• Identity: 269/816 - (32%)
• Similarity: 417/816 - (51%)
• Gaps: 127/816 - (15%)

  Fly     6 SSKKNQVTWYHCESCGVHIPSKARDNHEGLCFAISQDDVGP---DSEAEYVRSGAIYTRSLQQRN 67
            ||.|.:.:...|..|...:.:|....|:..|        |.   :||....::|.:       |.
 Worm     2 SSAKKKPSLVTCPQCNAVVLTKDSLRHQDFC--------GKPVVESEIACAQNGTL-------RG 51

  Fly    68 FEVESLKDLPTKYANMLVFVSEG-----AMQLAQLH---IGQHVVLEAPSTAEQPLVRIVWPTSE 124
            |             |:.|..:||     |:...:.|   |.|..:......|.|| |||: .:|:
 Worm    52 F-------------NVAVDKAEGFLPPDAVGWEKEHSILINQQTMESLGLLARQP-VRII-HSSD 101

  Fly   125 QFLTTVFVSEGDFKLHCTQLRGKLLKISALHPSRLTAAASISLKHVNTTE-------TSLKSVQL 182
            .|:..|:        .|.::  .|||:|.: .||:.....|:|:.....|       |...|:.|
 Worm   102 SFIGIVW--------PCKEV--ALLKVSII-SSRIARERMITLESCGRVEKLKSLSVTVKTSLTL 155

  Fly   183 QDAIA-LLKRDMVNRVFYKDSLIHMNFFNKSLTFRLERWQSTVEEALAGLSLDSKPLQFIQVTNV 246
            ..|:: .|:..:.:.....:|.:.:.:..:::|...|   ..:|..::.:.:|....:..:|.:.
 Worm   156 NPALSGFLEAYLSHSYLQYNSSVDLKYLGQNVTVTPE---EPIESKMSAMGIDDDKKRNSKVVST 217

  Fly   247 T---KLHLITDDANQQEEEQKISHRITKCQIGGLDRQLQLVEESMEYALGFRTLPAGLRVSRGLL 308
            .   |:.::...|.....:...:.......|||.....|::|:.:...:..:..|.      .:|
 Worm   218 AVGYKIQILNASAEGSTSDVLQTLPTDLSNIGGCFTAKQVLEDYVISPVRQKESPC------SVL 276

  Fly   309 LYGATGCGKSMVLEAMCAVAEERSQGHVQLIRINSGEVYSKFLGETEQKLGAIFERAYNHYPHPT 373
            ::|..|.||:::|:.:..|.              ||.  :.::|..|:.:........|
 Worm   277 IWGLPGSGKTLLLKEVALVL--------------SGS--TTYIGSCEELMELNGVTTGN------ 319

  Fly   374 LLLIEDVHNLCPKQENSDLVKRVSLAFLSLLDQLSSPSQLKGSKTFVLATSSQIDTLHPSIRRAG 438
             ::|.||:.|  ::||:...:  :|:||           |...|..|:......:||....|  .
 Worm   320 -IVIVDVNEL--EKENTKANR--ALSFL-----------LGDEKKCVILCVRSSETLDIGFR--V 366

  Fly   439 RLDNEVELGAPSSQARLEIVRCL--IKSVEHQLSDEEVEHVASITHGYVGADLANLVYAAMLQAQ 501
            |...|.|:..|:...||:|:..:  |.:...:|..:...|    |||:.|.||.:|:.||.....
 Worm   367 RFPIEAEITVPTQDERLDILSKIGNIYNFPLELHLDVARH----THGFTGGDLCSLLKAAKFARG 427

  Fly   502 PNPLQMPHLQAALTRIKPSAMREVLIECPNVQWSDIGGQSELRLAMQQAIEWPLLHADKFQRLGI 566
            ...|:  .:..|..||:|:.:|:.::|.|||.|:||||..||:|.:|||:.||..|.:.|:|.||
 Worm   428 RTHLE--RVNDARKRIRPTGIRQFILEVPNVSWNDIGGNEELKLEIQQAVIWPQKHPEAFERFGI 490

  Fly   567 KPPRGILMFGPPGCSKTMIAKALATESKLNFLSIKGPELFSMWVGESERAVREVFRKARQVAPAI 631
            .||.|||::||||||||:||:|||:|:|:|||::|||||||.|||:||:|:|::|.:||||||.|
 Worm   491 DPPAGILLYGPPGCSKTLIARALASEAKMNFLAVKGPELFSKWVGDSEKAIRDLFSRARQVAPTI 555

  Fly   632 VFFDEIDAIGGERSEGDGSSSGSSVKERVLTQLLTELDGVEALQNVTIVAATNRPDMIDKALLRP 696
            ||||||||:|..|    ||...|.|.:|||.||||||||:|....|.::|||||||.:|.|||||
 Worm   556 VFFDEIDAVGSSR----GSEKSSGVSDRVLAQLLTELDGLEKSSRVILLAATNRPDQLDSALLRP 616

  Fly   697 GRIDRILYVGLPQCE-ARREILKIKLRAMPISNDV-DMEKLVQLTEGYSGAEIQAVCHEAALRAL 759
            ||:||.:||||| || .||.||:::.:.|...:.| .::|||:.|.||||||:.|||..||:.|:
 Worm   617 GRLDRAIYVGLP-CEVTRRAILEMRTKKMKFDDTVRTIDKLVEKTSGYSGAELVAVCRTAAMFAM 680

  Fly   760 EQSFEAEDVKWTDFEHALKAVPPRTSPELLKLYEDY 795
            .:|.:|..|:||.||.||.||..||...||::|:|:
 Worm   681 RESIDATIVQWTHFEQALAAVVSRTEAYLLEIYDDF 716

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5776	NP_609585.1	CDC48	183..797	CDD:273521	225/621 (36%)
cdc-48.3	NP_492211.1	CDC48	<247..720	CDD:273521	215/527 (41%)