Protein Alignment CG5776 and Pex6

DIOPT Version :10

• Sequence 1: NP_609585.1
• Gene: CG5776 / 34680
• FlyBaseID: FBgn0032450
• Length: 799
• Species: Drosophila melanogaster
• Sequence 2: XP_321486.5
• Gene: Pex6 / 1281560
• VectorBaseID: AGAMI1_015138
• Length: 835
• Species: Anopheles gambiae
• Alignment Length: 803
• Identity: 214/803 - (26%)
• Similarity: 367/803 - (45%)
• Gaps: 154/803 - (19%)

  Fly    92 MQLAQLHIGQHVVLEAPSTAEQPLV--RIVW---------------PT-SEQFLTTVFVSEGDFK 138
            :|..||...:|.:..:|:...:.:|  .|.|               || .::.|.::.:::.|..
Mosquito    64 LQSDQLVASEHTLFVSPTVFREYVVEREINWINLVLKVAKCSEQVEPTPQDKSLVSIILNKQDVS 128

  Fly   139 LHC---------------------------TQLRG-----KLLKIS-ALHPSRLTAAASISL--- 167
            |.|                           |:..|     :|.:|: ..|...:.|.|:|.|
Mosquito   129 LLCQVAPHADVPLNALWVKENLVENLNERYTRHTGERYWARLQRITEGQHLPAIVAKANIFLYQT 193

  Fly   168 --------------KHVNTTETSLKSVQLQDAIALLKRDMVNRVFYKD--SLIHMNFFNKSLTFR 216
                          ::..|.....::...|  :.|.:|.:.|..:.|.  .|:||    :||.|:
Mosquito   194 PYDLSSDMVDFILGRYFETPRLLYRNHTYQ--VPLTERFLGNTFYTKHFAVLVHM----RSLWFK 252

  Fly   217 LERWQSTVEE-ALAGLSLDSKPLQFIQVTNVTKLHLITDDANQQEEEQKISHRITKCQIGGLDRQ 280
            .....||... .::|::  .|.|..:|.|......|:       .|.....:....|.. ||.:.
Mosquito   253 CLNLDSTAGAFEMSGIA--QKSLTTLQQTTTYNNFLL-------PERFDGPYMRPSCPF-GLRKY 307

  Fly   281 LQLVEESMEYALGFRTLPAGLRVSRGL----LLYGATGCGKSMVLEAMCAVAEERSQGHVQLIRI 341
            ...:..|::..|....  .|| |..|:    :|.|..|.||..||.::.:..      .:.:...
Mosquito   308 FHSLRSSLQAYLKMEN--NGL-VRNGIYPVFMLRGERGIGKMAVLRSVASAL------GIPIYYA 363

  Fly   342 NSGEVYSKFLGETEQKLGAIFERAYNHYPHPTLLLIEDVHNLCPKQENSDLVKRVSLAFLSLL-- 404
            :..|:.:....:||.||...|.:|  ....|.::.:|:........|..: .:|::.:|.:.|
Mosquito   364 DCSEIMTSISSQTETKLSTAFNKA--KVCEPLIICLENFEVFGVDNEGHE-DQRITGSFQAELMT 425

  Fly   405 ---DQLSSPSQLKGSKTFVLATSSQIDTLHPSIRRAGRLDNEVELGAPSSQARLEIVRCLIKSVE 466
               .|.|.|       ..|:|.::|.::..|.:  .......::|.||::..|||::|.:.....
Mosquito   426 LFGRQYSHP-------VVVVAVANQKESNTPKL--TSLFLEVIQLHAPTTAERLELLRWISLGHR 481

  Fly   467 HQLSDEEVEHVASITHGYVGADLANLVYAAMLQA-----QPNPLQMPHLQAALTRIKPSAMREVL 526
            ::|...:::.:|..:.|:..||| .|:|...|:|     ....:.:.|..|.|..:: |...:.|
Mosquito   482 YRLPVGQLQKIAEQSQGFTLADL-ELLYGNALEAWRRSQDTGRVGLNHFLALLDHMQ-STFSDSL 544

  Fly   527 --IECPNVQWSDIGGQSELRLAMQQAIEWPLLHADKFQRLGIKPPR-GILMFGPPGCSKTMIAKA 588
              .:.|.|.||:|||.::|:..:|.:|..||.|.   ..:|....| |||::||||..||:||||
Mosquito   545 GAPKVPKVLWSEIGGLAKLKSEIQNSIGLPLRHK---HLMGKNMRRSGILLYGPPGTGKTLIAKA 606

  Fly   589 LATESKLNFLSIKGPELFSMWVGESERAVREVFRKARQVAPAIVFFDEIDAIGGERSEGDGSSSG 653
            :|||..|:|||::||||.:|:||:||:.|||||.:||..:|.::|.||:|::...|.. .|.|.|
Mosquito   607 VATECNLSFLSVQGPELLNMYVGQSEQNVREVFARARTASPCVLFLDELDSLAPNRGV-SGDSGG 670

  Fly   654 SSVKERVLTQLLTELDGV--EALQNVTIVAATNRPDMIDKALLRPGRIDRILYVGLPQC--EARR 714
              |.:||::|:|:|:||:  :..|.:.|:|||||||:||.|||||||.|::|||| |.|  |.:.
Mosquito   671 --VMDRVVSQMLSEMDGISKDPGQQIFILAATNRPDLIDPALLRPGRFDKLLYVG-PSCTVEDKE 732

  Fly   715 EILKIKLRAMPISNDVDMEKLVQ-LTEGYSGAEIQAVCHEAALRA-------------LEQSFEA 765
            .:|:.......::..:.:.|:.: |.:..:||::.::|..|.|.|             :::...|
Mosquito   733 SVLRAVTGRFRLAETLTLRKIAESLKQDMTGADMYSICSNAWLSAVRRTVKEAIAGDSIDEGLNA 797

  Fly   766 EDVKWT--DFEHALKAVPPRTSP 786
            :.|..|  ||:.::|...|..||
Mosquito   798 DQVIVTEDDFKESVKKFIPSISP 820

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5776	NP_609585.1	CDC48	183..797	CDD:273521	190/644 (30%)
Pex6	XP_321486.5	None