Protein Alignment PICK1 and Pick1

DIOPT Version :10

• Sequence 1: NP_001285881.1
• Gene: PICK1 / 34677
• FlyBaseID: FBgn0032447
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_445912.2
• Gene: Pick1 / 84591
• RGDID: 69437
• Length: 416
• Species: Rattus norvegicus
• Alignment Length: 379
• Identity: 223/379 - (58%)
• Similarity: 283/379 - (74%)
• Gaps: 1/379 - (0%)

  Fly    85 ELDRLGMTVSTNAVVITKDQSNLIGISIGGGAPMCPCLYIVQIFDGTPAAREGSLQSGDELLAVN 149
            |.|:||:......|.:.||..|||||||||||..||||||||:||.||||.:|::.:|||:..||
  Rat    10 EEDKLGIPTVPGKVTLQKDAQNLIGISIGGGAQYCPCLYIVQVFDNTPAALDGTVAAGDEITGVN 74

  Fly   150 SVSVKGKTKVEVAKMIQTATDEVVIHYNKLHADPEQGKTLDIILKKLKHRIVDNLSSNTADTLGL 214
            ..|:|||||||||||||....||.||||||.|||:||.:|||:|||:|||:|:|:||.|||.|||
  Rat    75 GRSIKGKTKVEVAKMIQEVKGEVTIHYNKLQADPKQGMSLDIVLKKVKHRLVENMSSGTADALGL 139

  Fly   215 SRAILCNDSLVKRLEELEGTELMYKGLVEHARRMLKAYYDLLQTYKSFGDCFTQISVHEPQQRAS 279
            ||||||||.|||||||||.|..:|||:.||.:.:|:|:|:|.||:::|||.|:.|.|.|||..||
  Rat   140 SRAILCNDGLVKRLEELERTAELYKGMTEHTKNLLRAFYELSQTHRAFGDVFSVIGVREPQPAAS 204

  Fly   280 EAFRTFGEFHRTLEKDGLGIIKQIKPVLADLGTYLNKAIPDTKLTVRRYADAKFTYLSYCLKVKE 344
            |||..|.:.||::||.|:.::|.|||:|.||.||||||||||:||:::|.|.||.||||||||||
  Rat   205 EAFVKFADAHRSIEKFGIRLLKTIKPMLTDLNTYLNKAIPDTRLTIKKYLDVKFEYLSYCLKVKE 269

  Fly   345 MDDEEHGFAALQEPLYRVETGNYEYRLILRCRQDARSKFAKLRTDVLEKMELLECKHAMDLNKQL 409
            |||||:...||.||||||.||||||||||||||:||::|:::|.|||||||||:.||..|:..||
  Rat   270 MDDEEYSCIALGEPLYRVSTGNYEYRLILRCRQEARARFSQMRKDVLEKMELLDQKHVQDIVFQL 334

  Fly   410 RSLLESLAELHRSLVDRLDSLPPLFPIEVDFKETDFQYKSSTLKPQELDDDEIE 463
            :..:.::::.:......|.. ..:||||||...|...|..:.....:.:|:|.|
  Rat   335 QRFVSTMSKYYNDCYAVLRD-ADVFPIEVDLAHTTLAYGPNQGGFTDGEDEEEE 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PICK1	NP_001285881.1	PDZ_PICK1-like	96..179	CDD:467205	54/82 (66%)
		BAR_PICK1	221..436	CDD:153343	123/214 (57%)
Pick1	NP_445912.2	PDZ_PICK1-like	21..104	CDD:467205	54/82 (66%)
		BAR_PICK1	146..360	CDD:153343	123/214 (57%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	373..416		3/15 (20%)