DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PICK1 and F54C8.7

DIOPT Version :9

Sequence 1:	NP_001285881.1	Gene:	PICK1 / 34677	FlyBaseID:	FBgn0032447	Length:	577	Species:	Drosophila melanogaster
Sequence 2:	NP_871661.1	Gene:	F54C8.7 / 176326	WormBaseID:	WBGene00010040	Length:	307	Species:	Caenorhabditis elegans

Alignment Length:	194	Identity:	46/194 - (23%)
Similarity:	77/194 - (39%)	Gaps:	23/194 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   229 EELEGTELMYKGLVEHARRMLKAYYDLLQTYKSFGDCFTQISVHEPQQRA-----SEAFRTFGEF 288
            |.|:.....|..:|..|:........:.:..|...:.|.|:|:.|.|.:|     ||..|..||.
Worm   101 EVLKDIHRRYGLVVAAAKNFSHVLTQMAEAEKKLSESFYQLSMKEEQIKAQCTMTSETMRGVGEQ 165

  Fly   289 HRTLEKDGLGIIKQIKPVLADLGTYLNKAIPDTKLTVRRYADAKFTYLSYCLKVKEMDDEEHGFA 353
            ..:|:       ..::..::.:.|..|:.|.||..|:.....|:..|          |.:.:..:
Worm   166 AASLD-------ACLRYFISSMETVYNQTITDTLHTIYNTESARIEY----------DVDRNDIS 213

  Fly   354 ALQEPLYRVETGNYEYRLILRCRQDARSKFAKLRTDVLEKMELLECKHAMDLNKQLRSLLESLA 417
            |...|.....|.|.......:| ::.::|:.||:.|...||.|||......:..||..|..:||
Worm   214 AATNPPQGQLTKNLPVGATEKC-EEKKAKYEKLKNDAKIKMRLLEENRISVVAAQLEKLQSALA 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PICK1	NP_001285881.1	PDZ_signaling	98..174	CDD:238492
PICK1	NP_001285881.1	BAR_PICK1	221..436	CDD:153343	46/194 (24%)
F54C8.7	NP_871661.1	BAR_Arfaptin	93..293	CDD:153344	46/194 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910