DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6153 and pithd1

DIOPT Version :9

Sequence 1:	NP_001162966.2	Gene:	CG6153 / 34675	FlyBaseID:	FBgn0032445	Length:	211	Species:	Drosophila melanogaster
Sequence 2:	NP_996957.1	Gene:	pithd1 / 404606	ZFINID:	ZDB-GENE-040426-2366	Length:	210	Species:	Danio rerio

Alignment Length:	199	Identity:	118/199 - (59%)
Similarity:	151/199 - (75%)	Gaps:	8/199 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 HGHSHDHG--GCSHEASDVDHALEMGIEYSLYTKIDLDNVECLNEETDGQGKSVFKPYEKRQDLS 65
            |||.|.||  .|.||.:      |.|:||.||.:||::.::||||..||.||.||||:::|.|.:
Zfish     6 HGHGHGHGCCECEHEPA------ERGVEYELYRRIDIEKLQCLNESRDGDGKLVFKPWDQRTDRN 64

  Fly    66 KYVESDADEELLFNIPFTGNIKLKGIIISGANDDSHPNMVKIFKNRPRMTFDDARAKPDQEFQLT 130
            |:|||||||||||||||||::|||||||||.:|:|||..:::|||.|:|:|||...:|:|.|:|.
Zfish    65 KFVESDADEELLFNIPFTGSVKLKGIIISGEDDESHPAEIRLFKNIPQMSFDDTSREPEQAFRLN 129

  Fly   131 RDARGEIEYSPKVVTFSSVHHLSLYFPSNFGEDITRIYYIGLRGEFTEAHYHGVTICNYESRANA 195
            ||.|.|:||..|:..||:|.|||::...|||.:.||:||||||||:||||.|.|||||||:.||.
Zfish   130 RDPRAELEYPTKIARFSNVEHLSIHVSRNFGAESTRVYYIGLRGEYTEAHRHEVTICNYEAAANP 194

  Fly   196 ADHK 199
            ||||
Zfish   195 ADHK 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6153	NP_001162966.2	PITH	31..175	CDD:283785	85/143 (59%)
pithd1	NP_996957.1	PITH	30..174	CDD:283785	85/143 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587263
Domainoid	1	1.000	195	1.000	Domainoid score	I3115
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10678
Inparanoid	1	1.050	256	1.000	Inparanoid score	I3150
OMA	1	1.010	-	-		QHG54146
OrthoDB	1	1.010	-	-		D1561790at2759
OrthoFinder	1	1.000	-	-		FOG0004940
OrthoInspector	1	1.000	-	-		oto41144
orthoMCL	1	0.900	-	-		OOG6_102988
Panther	1	1.100	-	-	LDO	PTHR12175
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R927
SonicParanoid	1	1.000	-	-		X2966
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.940