DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CCT4 and CCT7

DIOPT Version :9

Sequence 1:	NP_609579.1	Gene:	CCT4 / 34674	FlyBaseID:	FBgn0032444	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_012424.1	Gene:	CCT7 / 853333	SGDID:	S000003647	Length:	550	Species:	Saccharomyces cerevisiae

Alignment Length:	530	Identity:	172/530 - (32%)
Similarity:	283/530 - (53%)	Gaps:	25/530 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 PTAKAFK---DKSKPTDVRLSNIQAAKAVSDAIRTSLGPRGMDKMIQAGNGEVSITNDGATILKQ 73
            ||....|   |.|:.....:|||.|..||.:|::.:|||.|.|.:|...|.:.:|:||||||||.
Yeast     8 PTIVVLKEGTDASQGKGQIISNINACVAVQEALKPTLGPLGSDILIVTSNQKTTISNDGATILKL 72

  Fly    74 MNVLHPAAKMLVELSRAQDVAAGDGTTSVVVIAGALLEACEKLLQKGLHPTAISDSFQRCSNKAV 138
            ::|:|||||.||::|||||...|||||||.::||.|::..:..|::|:....|...:::..:.||
Yeast    73 LDVVHPAAKTLVDISRAQDAEVGDGTTSVTILAGELMKEAKPFLEEGISSHLIMKGYRKAVSLAV 137

  Fly   139 EILKQMSTPI---ELDDRETLIKSASTSLNSKVVSQQSSLLAPIAVDAVLKVTDPGKETSVDLKN 200
            |.:.:::..|   :...||.|.:.|.|:::||::...:.....:.|||||.:    ....:|.|.
Yeast   138 EKINELAVDITSEKSSGRELLERCARTAMSSKLIHNNADFFVKMCVDAVLSL----DRNDLDDKL 198

  Fly   201 IKVISSLGGTVEDTELVDGLVF--TCRSAG-SNAPKRIEKAKI-GL-IQFCISAPKTDMDHNV-I 259
            |.:....||.:|::..::|:.|  |...|| ...||:....|| .| ::..:.|.|.:.:..| .
Yeast   199 IGIKKIPGGAMEESLFINGVAFKKTFSYAGFEQQPKKFNNPKILSLNVELELKAEKDNAEVRVEH 263

  Fly   260 VSDYAAMDRVLKEERSYILNIVKQIKKSGCNVLLVQKSILRDAVSDLAQHFLDKIKCMVVKDVER 324
            |.||.|   ::..|...|...::|::::|.|::|.:..|     .|||..|...........|..
Yeast   264 VEDYQA---IVDAEWQLIFEKLRQVEETGANIVLSKLPI-----GDLATQFFADRNIFCAGRVSA 320

  Fly   325 EDIEFVCKTLHCRPIASLDHFTAENLSSADLVEEVASGTNKFVKITGIQNMGRTVSIICRGSNKL 389
            :|:..|.:.:.....::......|:|.:..|.||:..|:.::....|.. ..:|.:::.||..:.
Yeast   321 DDMNRVIQAVGGSIQSTTSDIKPEHLGTCALFEEMQIGSERYNLFQGCP-QAKTCTLLLRGGAEQ 384

  Fly   390 VLEEAARSLHDALCVVRCLVKLRAQIVGGGAPEIEMALQLAALAQTVEGVDAYCFRAFADALEVI 454
            |:.|..||||||:.:|:..::.:..:.||||.|:|::..|...::|:.|.......|||.|||||
Yeast   385 VIAEVERSLHDAIMIVKRALQNKLIVAGGGATEMEVSKCLRDYSKTIAGKQQMIINAFAKALEVI 449

  Fly   455 PSTLAENAGLNPIATVTELRNRHAQGEKNAGINVRKGAITDIFAENVVQPLLVSISSITLATETI 519
            |..|.||||.:.|..:.:||..|::|||..|:......|.|.||:.|.:|.||.|:::..|||..
Yeast   450 PRQLCENAGFDAIEILNKLRLAHSKGEKWYGVVFETENIGDNFAKFVWEPALVKINALNSATEAT 514

  Fly   520 RSILKIDDIV 529
            ..||.:|:.:
Yeast   515 NLILSVDETI 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCT4	NP_609579.1	TCP1_delta	18..531	CDD:239454	170/524 (32%)
CCT4	NP_609579.1	Cpn60_TCP1	37..529	CDD:278544	162/500 (32%)
CCT7	NP_012424.1	TCP1_eta	9..529	CDD:239456	171/529 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60896
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820