Protein Alignment CCT4 and CCT6

DIOPT Version :10

• Sequence 1: NP_609579.1
• Gene: CCT4 / 34674
• FlyBaseID: FBgn0032444
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_010474.3
• Gene: CCT6 / 851768
• SGDID: S000002596
• Length: 546
• Species: Saccharomyces cerevisiae
• Alignment Length: 539
• Identity: 142/539 - (26%)
• Similarity: 263/539 - (48%)
• Gaps: 40/539 - (7%)

  Fly    18 KDKSKPTDVRLS-NIQAAKAVSDAIRTSLGPRGMDKMIQAGNGEVSITNDGATILKQMNVLHPAA 81
            |.:|...|..|. |:.:|:.:...:.|:|||:|..||:..|.|.:.:|.||..:|.:|.:..|.|
Yeast     9 KAESLRRDAALKVNVTSAEGLQSVLETNLGPKGTLKMLVDGAGNIKLTKDGKVLLTEMQIQSPTA 73

  Fly    82 KMLVELSRAQDVAAGDGTTSVVVIAGALLEACEKLLQKGLHPTAISDSFQRCSNKAVEILKQ--M 144
            .::...:.|||...|||||:||.:.|.||....:.:|:|:||..|:|.|:....::::.|.:  :
Yeast    74 VLIARAAAAQDEITGDGTTTVVCLVGELLRQAHRFIQEGVHPRIITDGFEIARKESMKFLDEFKI 138

  Fly   145 STPIELDDRETLIKSASTSLNSKVVSQQSSLLAPIAVDAVLKVTDPGKETSVDLKNIKVISSLGG 209
            |.....:|||.|::.|.:||.:||.:..:.:|.||..||||.|.| .:..::||..::::.....
Yeast   139 SKTNLSNDREFLLQVARSSLLTKVDADLTEVLTPIVTDAVLSVYD-AQADNLDLHMVEIMQMQHL 202

  Fly   210 TVEDTELVDGLVFTCRSAGSNAPKRIEKAKIGLIQFCISAPKTDMDHNVIVSDYAAMDRVLKEER 274
            :.:||..:.|||........:.|.|::.|.:.::...:...||:::.....|.....|::...||
Yeast   203 SPKDTTFIKGLVLDHGGRHPDMPTRVKNAYVLILNVSLEYEKTEVNSGFFYSSADQRDKLAASER 267

  Fly   275 SYI---LNIVKQIKKSGCN-------VLLVQKSILRDAVSDLAQHFLDKIKCMVVKDVEREDIEF 329
            .::   |..:..:|...|.       |::.||.|...::...|:|     ..:.::..:|.::|.
Yeast   268 KFVDAKLKKIIDLKNEVCGMDPDKGFVIINQKGIDPMSLDVFAKH-----NILALRRAKRRNMER 327

  Fly   330 VCKTLHCRPIASLDHFTAENLSSADLVEEVASGTNKFVKITGIQNMG-RTVSIICRGSNKLVLEE 393
            :..........|::..:.:.|..:.||.:...|..||..:|  :|.. ::.:|:.:||....|.:
Yeast   328 LQLVTGGEAQNSVEDLSPQILGFSGLVYQETIGEEKFTYVT--ENTDPKSCTILIKGSTHYALAQ 390

  Fly   394 AARSLHDALCVVRCLVKLRAQIVGGGAPEIEMAL--------QLAALAQTVEGVDAYCFRAFADA 450
            ...::.|.|..|..::|.:..|.|.||..|.::.        :|.|..:|..|::     |||:|
Yeast   391 TKDAVRDGLRAVANVLKDKNIIPGAGAFYIALSRYLRSANMNKLGAKGKTKTGIE-----AFAEA 450

  Fly   451 LEVIPSTLAENAGLNPIATVT----ELRNRHAQGE-KNAGINVRKGAITDIFAENVVQPLLVSIS 510
            |.|||.||.:|:|.:|:..:.    ||.:.....| :..|:::..|...|...|.:.....|..:
Yeast   451 LLVIPKTLVKNSGFDPLDVLAMVEDELDDAQDSDETRYVGVDLNIGDSCDPTIEGIWDSYRVLRN 515

  Fly   511 SITLATETIRSILKIDDIV 529
            :||.||....::|..|:::
Yeast   516 AITGATGIASNLLLCDELL 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT4	NP_609579.1	TCP1_delta	18..531	CDD:239454	142/539 (26%)
CCT6	NP_010474.3	chap_CCT_zeta	2..542	CDD:274088	142/539 (26%)