DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CCT4 and AT3G18190

DIOPT Version :9

Sequence 1:	NP_609579.1	Gene:	CCT4 / 34674	FlyBaseID:	FBgn0032444	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_188447.1	Gene:	AT3G18190 / 821346	AraportID:	AT3G18190	Length:	536	Species:	Arabidopsis thaliana

Alignment Length:	535	Identity:	350/535 - (65%)
Similarity:	428/535 - (80%)	Gaps:	8/535 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAPKAAAVNIKP---TAKAFKDKSKPTDVRLSNIQAAKAVSDAIRTSLGPRGMDKMIQAGNGEVS 62
            ||..||.:..||   .|::|.|..:..|:|.:||.:|:|||||:||||||:||||||...||||.
plant     1 MAAVAAPMASKPRGSKAESFVDNKRREDIRFANINSARAVSDAVRTSLGPKGMDKMISTANGEVI 65

  Fly    63 ITNDGATILKQMNVLHPAAKMLVELSRAQDVAAGDGTTSVVVIAGALLEACEKLLQKGLHPTAIS 127
            |||||||||.:|.||.||||||||||::||.|||||||:|||||||||:.|:.||..|:|||.||
plant    66 ITNDGATILNKMEVLQPAAKMLVELSKSQDSAAGDGTTTVVVIAGALLKECQSLLTNGIHPTVIS 130

  Fly   128 DSFQRCSNKAVEILKQMSTPIELDDRETLIKSASTSLNSKVVSQQSSLLAPIAVDAVLKVTDPGK 192
            ||..:...||::||..|:.|:||.||::|:||||||||||||||.|:||||:||||||.|.||.|
plant   131 DSLHKACGKAIDILTAMAVPVELTDRDSLVKSASTSLNSKVVSQYSTLLAPLAVDAVLSVIDPEK 195

  Fly   193 ETSVDLKNIKVISSLGGTVEDTELVDGLVF---TCRSAGSNAPKRIEKAKIGLIQFCISAPKTDM 254
            ...|||::||::..|||||:||..|.||||   ..|:||  .|.|:|.|||.:|||.||.||||:
plant   196 PEIVDLRDIKIVKKLGGTVDDTHTVKGLVFDKKVSRAAG--GPTRVENAKIAVIQFQISPPKTDI 258

  Fly   255 DHNVIVSDYAAMDRVLKEERSYILNIVKQIKKSGCNVLLVQKSILRDAVSDLAQHFLDKIKCMVV 319
            :.:::||||..|||:|||||:|||.::|:||.:||||||:|||||||||:||:.|:|.|.|.||:
plant   259 EQSIVVSDYTQMDRILKEERNYILGMIKKIKATGCNVLLIQKSILRDAVTDLSLHYLAKAKIMVI 323

  Fly   320 KDVEREDIEFVCKTLHCRPIASLDHFTAENLSSADLVEEVASGTNKFVKITGIQNMGRTVSIICR 384
            |||||::||||.|||:|.|||:::||.||.|..||||||.:.|..|.:|||||::||||.|::.|
plant   324 KDVERDEIEFVTKTLNCLPIANIEHFRAEKLGHADLVEEASLGDGKILKITGIKDMGRTTSVLVR 388

  Fly   385 GSNKLVLEEAARSLHDALCVVRCLVKLRAQIVGGGAPEIEMALQLAALAQTVEGVDAYCFRAFAD 449
            |||:|||:||.||||||||||||||..|..|.||||||||::.||.|.|:.:.|::.||.::||:
plant   389 GSNQLVLDEAERSLHDALCVVRCLVSKRFLIAGGGAPEIELSRQLGAWAKVLHGMEGYCVKSFAE 453

  Fly   450 ALEVIPSTLAENAGLNPIATVTELRNRHAQGEKNAGINVRKGAITDIFAENVVQPLLVSISSITL 514
            ||||||.||||||||||||.||||||:|||||.|||||||||.||:|..||||||||||.|:|||
plant   454 ALEVIPYTLAENAGLNPIAIVTELRNKHAQGEINAGINVRKGQITNILEENVVQPLLVSTSAITL 518

  Fly   515 ATETIRSILKIDDIV 529
            |||.:|.||||||||
plant   519 ATECVRMILKIDDIV 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCT4	NP_609579.1	TCP1_delta	18..531	CDD:239454	342/515 (66%)
CCT4	NP_609579.1	Cpn60_TCP1	37..529	CDD:278544	333/494 (67%)
AT3G18190	NP_188447.1	TCP1_delta	22..535	CDD:239454	342/514 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	653	1.000	Domainoid score	I26
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4695
Inparanoid	1	1.050	674	1.000	Inparanoid score	I148
OMA	1	1.010	-	-		QHG60896
OrthoDB	1	1.010	-	-		D511484at2759
OrthoFinder	1	1.000	-	-		FOG0004921
OrthoInspector	1	1.000	-	-		oto3934
orthoMCL	1	0.900	-	-		OOG6_101757
Panther	1	1.100	-	-	LDO	PTHR11353
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3470
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840