Protein Alignment CCT4 and TCP1

DIOPT Version :9

• Sequence 1: NP_609579.1
• Gene: CCT4 / 34674
• FlyBaseID: FBgn0032444
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_110379.2
• Gene: TCP1 / 6950
• HGNCID: 11655
• Length: 556
• Species: Homo sapiens
• Alignment Length: 533
• Identity: 166/533 - (31%)
• Similarity: 285/533 - (53%)
• Gaps: 29/533 - (5%)

  Fly    17 FKDKSKPTDVRLSNIQAAKAVSDAIRTSLGPRGMDKMIQAGNGEVSITNDGATILKQMNVLHPAA 81
            |.|:|....:|..|:.||.::::.:::||||.|:|||:....|:|:||||||||||.:.|.||||
Human     8 FGDRSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAA 72

  Fly    82 KMLVELSRAQDVAAGDGTTSVVVIAGALLEACEKLLQKGLHPTAISDSFQRCSNKAVEILKQMST 146
            |:|.||:..||...||||||||:||..||:..::|:::.:|||::...::....:||..:.: :.
Human    73 KVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINE-NL 136

  Fly   147 PIELDD--RETLIKSASTSLNSKVVSQQSSLLAPIAVDAVL--KVTDPGKETSVDLKNIKVISSL 207
            .:..|:  |:.||.:|.||::||::.......|.:.|||||  |.||...:....:.::.::.:.
Human   137 IVNTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVNSVNILKAH 201

  Fly   208 GGTVEDTELVDGLVFTCRSAGSNAPKRIEKAKIGLIQFCISAPKTDMDHNVIVSDYAAMDRVLKE 272
            |.:..::.|:.|....|.......||||..|||..:.|.:...|..:...|:::|...:|::.:.
Human   202 GRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQR 266

  Fly   273 ERSYILNIVKQIKKSGCNVLLVQKSILRDAVSDLAQHFLDKIKCMVVKDVEREDIEFVCKTLHCR 337
            |.......:::|..:|.||:|.     ...:.|:...:..:...|.|:.|.:.|::.:.|.....
Human   267 ESDITKERIQKILATGANVILT-----TGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGAT 326

  Fly   338 PIASL------DHFTAENLSSADLV--EEVASGTNKFVKITGIQNMGRTVSIICRGSNKLVLEEA 394
            .:::|      :.|.|..|..|:.|  |.:.......:|.|..:.   :.|||.||:|..:.:|.
Human   327 ILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTKART---SASIILRGANDFMCDEM 388

  Fly   395 ARSLHDALCVVRCLVKLRAQIVGGGAPEIEMALQLAALAQTVEGVDAYCFRAFADALEVIPSTLA 459
            .||||||||||:.:::.::.:.||||.|..:::.|...|.::...:......||.:|.|||:|||
Human   389 ERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLA 453

  Fly   460 ENAGLNPIATVTELRNRHAQGEKN--------AGINVRKGAITDIFAENVVQPLLVSISSITLAT 516
            .||..:....|.:||..|.:.:.|        .|:::..|...|.....|.:|.:|.:.|:..||
Human   454 VNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFAT 518

  Fly   517 ETIRSILKIDDIV 529
            |...:||:|||::
Human   519 EAAITILRIDDLI 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT4	NP_609579.1	TCP1_delta	18..531	CDD:239454	165/532 (31%)
		Cpn60_TCP1	37..529	CDD:278544	159/511 (31%)
TCP1	NP_110379.2	TCP1_alpha	9..535	CDD:239451	165/532 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60896
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820