Protein Alignment CCT4 and HSPD1

DIOPT Version :9

• Sequence 1: NP_609579.1
• Gene: CCT4 / 34674
• FlyBaseID: FBgn0032444
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_002147.2
• Gene: HSPD1 / 3329
• HGNCID: 5261
• Length: 573
• Species: Homo sapiens
• Alignment Length: 560
• Identity: 117/560 - (20%)
• Similarity: 240/560 - (42%)
• Gaps: 86/560 - (15%)

  Fly    18 KDKSKPTDVRLSNIQAAKAVSDAIRTSLGPRGMDKMIQAGNGEVSITNDGATILKQMNV----LH 78
            ||.....|.|...:|....::||:..::||:|...:|:...|...:|.||.|:.|.:::    .:
Human    28 KDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKN 92

  Fly    79 PAAKMLVELSRAQDVAAGDGTTSVVVIAGALLEACEKLLQKGLHPTAISDSFQRCSNKAVEILKQ 143
            ..||::.:::...:..||||||:..|:|.::.:...:.:.||.:|..|........:..:..||:
Human    93 IGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKK 157

  Fly   144 MSTPIELDDRETLIKSASTSLNSKVVSQQSSLLAPIAVDAVLKVTDPGKETSVDLKNIKVISSLG 208
            .|.|:...  |.:.:.|:.|.|.      ...:..|..||:.||   |::..:.:|:.|.::
Human   158 QSKPVTTP--EEIAQVATISANG------DKEIGNIISDAMKKV---GRKGVITVKDGKTLN--- 208

  Fly   209 GTVEDTELVDGL---------VFTCRSAG-----SNAPKRIEKAKIGLIQFCISAPKTDMDHN-- 257
               ::.|:::|:         .|...|.|     .:|...:.:.||..||..:.|.:....|.
Human   209 ---DELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSIQSIVPALEIANAHRKP 270

  Fly   258 -VIVS---DYAAMDRVLKEERSYILNIVKQIKKSGCNVLLV--------QKSILRD-AVSDLAQH 309
             ||::   |..|:.       :.:||.:    |.|..|:.|        :|:.|:| |::.....
Human   271 LVIIAEDVDGEALS-------TLVLNRL----KVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAV 324

  Fly   310 FLDKIKCMVVKDVEREDIEFVCKTLHCRPIASL-----DHFTAENLSSADLVEEVASGTNKFVKI 369
            |.::...:.::||:..|:..|.:.:..:..|.|     |....|. ...:::|::...|:::.|.
Human   325 FGEEGLTLNLEDVQPHDLGKVGEVIVTKDDAMLLKGKGDKAQIEK-RIQEIIEQLDVTTSEYEKE 388

  Fly   370 TGIQNMGRT---VSII-CRGSNKLVLEEAARSLHDALCVVRCLVKLRAQIVGGGAPEIEMALQLA 430
            ...:.:.:.   |::: ..|::.:.:.|....:.|||...|..|: ...::|||...:.....|.
Human   389 KLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVE-EGIVLGGGCALLRCIPALD 452

  Fly   431 ALAQTVE----GVDAYCFRAFADALEVIPSTLAENAGLNPIATVTELRNRHAQGEKNAGINVRKG 491
            :|....|    |::     .....|::...|:|:|||:.....|.::    .|.....|.:...|
Human   453 SLTPANEDQKIGIE-----IIKRTLKIPAMTIAKNAGVEGSLIVEKI----MQSSSEVGYDAMAG 508

  Fly   492 AITDIFAENVVQPLLVSISSITLATETIRSILKIDDIVNT 531
            ...::..:.::.|..| :.:..|....:.|:|...::|.|
Human   509 DFVNMVEKGIIDPTKV-VRTALLDAAGVASLLTTAEVVVT 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT4	NP_609579.1	TCP1_delta	18..531	CDD:239454	116/558 (21%)
		Cpn60_TCP1	37..529	CDD:278544	110/537 (20%)
HSPD1	NP_002147.2	GroEL	28..548	CDD:239460	117/560 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810