DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CCT4 and tcp1

DIOPT Version :9

Sequence 1:	NP_609579.1	Gene:	CCT4 / 34674	FlyBaseID:	FBgn0032444	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_571305.1	Gene:	tcp1 / 30477	ZFINID:	ZDB-GENE-990714-24	Length:	556	Species:	Danio rerio

Alignment Length:	527	Identity:	169/527 - (32%)
Similarity:	279/527 - (52%)	Gaps:	29/527 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 VRLSNIQAAKAVSDAIRTSLGPRGMDKMIQAGNGEVSITNDGATILKQMNVLHPAAKMLVELSRA 90
            ||..|:.||.::::.:::||||.|:|||:....|:|:||||||||||.:.|.|||||:|.||:..
Zfish    18 VRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVLCELAEL 82

  Fly    91 QDVAAGDGTTSVVVIAGALLEACEKLLQKGLHPTAISDSFQRCSNKAVEILKQMSTPIELDD--R 153
            ||...||||||||:||..||::.::|:::.:|||:|...::....:||..:.:..| |..||  |
Zfish    83 QDKEVGDGTTSVVIIAAELLKSADELVKQKIHPTSIISGYRLACKEAVRYINENLT-IGTDDLGR 146

  Fly   154 ETLIKSASTSLNSKVVSQQSSLLAPIAVDA--VLKVTDPGKETSVDLKNIKVISSLGGTVEDTEL 216
            |.|:.:|.||::||::...:...|.:.|||  .:|..|........:.::.|:.:.|.:.:::.|
Zfish   147 ECLLNAAKTSMSSKIIGVDAEFFANMVVDAAVAVKFVDGKGVARYPINSVNVLKAHGRSQKESFL 211

  Fly   217 VDGLVFTCRSAGSNAPKRIEKAKIGLIQFCISAPKTDMDHNVIVSDYAAMDRVLKEERSYILNIV 281
            |:|....|........||:..|||..:.|.:...|..:...|:::|...:|::.:.|.......|
Zfish   212 VNGYALNCTVGSQGMVKRVANAKIACLDFSLQKTKMKLGVQVVINDPEKLDQIRQRESDITKERV 276

  Fly   282 KQIKKSGCNVLLVQKSILRDAVSDLAQHFLDKIKCMVVKDVEREDIEFVCKTLHCRPIASLDHFT 346
            ::|..||.||:|.     ...:.|:...:...:..|.|:.|.::|::.:.|.......:||.:..
Zfish   277 QKILASGANVVLT-----TGGIDDMCLKYFVDVGAMAVRRVLKKDLKRIAKATGATVCSSLSNLE 336

  Fly   347 AEN------LSSADLV--EEVASGTNKFVKITGIQNMGRTVSIICRGSNKLVLEEAARSLHDALC 403
            .|.      |..|:.|  |.|.......:|.|..:.   :.|||.||:|..:.:|..||||||||
Zfish   337 GEETFEPSMLGQAEEVVQERVCDDELILIKNTKART---SASIILRGANDFMCDEMERSLHDALC 398

  Fly   404 VVRCLVKLRAQIVGGGAPEIEMALQLAALAQTVEGVDAYCFRAFADALEVIPSTLAENAGLNPIA 468
            ||:.:::.::.:.||||.|..:::.|...|.::...:......||.:|.|||.|||.||..:...
Zfish   399 VVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPKTLAVNAAQDSTD 463

  Fly   469 TVTELRNRHAQGEKN--------AGINVRKGAITDIFAENVVQPLLVSISSITLATETIRSILKI 525
            .|.:||..|.:.:.|        .|:::..|...|.....|.:|.:|...|:..|||...:||:|
Zfish   464 LVAKLRAFHNEAQVNPDRKNLKWIGLDLVNGKPRDNKQAGVYEPTMVKTKSLKFATEAAITILRI 528

  Fly   526 DDIVNTF 532
            ||::..|
Zfish   529 DDLIKLF 535

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCT4	NP_609579.1	TCP1_delta	18..531	CDD:239454	168/524 (32%)
CCT4	NP_609579.1	Cpn60_TCP1	37..529	CDD:278544	163/511 (32%)
tcp1	NP_571305.1	chap_CCT_alpha	6..541	CDD:274081	169/527 (32%)
tcp1	NP_571305.1	TCP1_alpha	10..536	CDD:239451	169/527 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60896
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920