Protein Alignment CCT4 and Cct8

DIOPT Version :10

• Sequence 1: NP_609579.1
• Gene: CCT4 / 34674
• FlyBaseID: FBgn0032444
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_001099367.2
• Gene: Cct8 / 288305
• RGDID: 1305452
• Length: 548
• Species: Rattus norvegicus
• Alignment Length: 536
• Identity: 159/536 - (29%)
• Similarity: 268/536 - (50%)
• Gaps: 25/536 - (4%)

  Fly     3 PKAA--AVNIKPTAKAFKDKSKPTDVRLSNIQAAKAVSDAIRTSLGPRGMDKMIQAGNGEVSITN 65
            |||.  |..:|..||.|   |...:....||||.|.::...||:.||.||:||:.....::.:||
  Rat     6 PKAPGFAQMLKDGAKHF---SGLEEAVYRNIQACKELAQTTRTAYGPNGMNKMVINRLEKLFVTN 67

  Fly    66 DGATILKQMNVLHPAAKMLVELSRAQDVAAGDGTTSVVVIAGALLEACEKLLQKGLHPTAISDSF 130
            |.||||:::.|.||||||:|..|..|:...||||..|:|.||||||..|:||:.||..:.:...:
  Rat    68 DAATILRELEVQHPAAKMIVMASHMQEQEVGDGTNFVLVFAGALLELAEELLRIGLSVSEVITGY 132

  Fly   131 QRCSNKAVEILKQM-----STPIELDDRETLIKSASTSLNSKVVSQQSSLLAPIAVDAVLKVTDP 190
            :....||.|||..:     ....::|:..:|::   ||:.||....:..|...|:...|....|.
  Rat   133 EIACKKAHEILPDLVCCSAKNLRDVDEVSSLLR---TSIMSKQYGSEEFLAKLISQACVSIFPDS 194

  Fly   191 GKETSVDLKNIKVISSLGGTVEDTELVDGLVFTCRSAGSNAPKRIEKAKIGLIQFCISAPKTDMD 255
            |   :.::.||:|...||..|..:.::.|:||...:.|.  ...::.|||.:.........|:..
  Rat   195 G---NFNVDNIRVCKILGSGVYSSSVLHGMVFKKETEGD--VTSVKDAKIAVYSCPFDGMITETK 254

  Fly   256 HNVIVSDYAAMDRVLKEERSYILNIVKQIKKSGCNVLLVQKSILRDAVSDLAQHFLDKIKCMVVK 320
            ..|::.....:....|.|.:.:...||.|..:|.||:     :....|:|:|.|:.:|...|:|:
  Rat   255 GTVLIKTAEELMNFSKGEENLMDAQVKAIAGTGANVI-----VTGGKVADMALHYANKYNIMLVR 314

  Fly   321 DVEREDIEFVCKTLHCRPIASLDHFTAENLSSADLVEEVASGTNKFVKITGIQNMGRTVSIICRG 385
            ...:.|:..:|||:....:..|.....|.:...|.|.....|..:.|.....:..|...:|:.||
  Rat   315 LNSKWDLRRLCKTVGATALPKLTPPVLEEMGHCDSVYLSEVGDTQVVVFKHEKEDGAISTIVLRG 379

  Fly   386 SNKLVLEEAARSLHDALCVVRCLVKLRAQIVGGGAPEIEMALQLAALAQTVEGVDAYCFRAFADA 450
            |...::::..|::.|.:...:.|.:.:..:.||||.|||:|.|:.:..:|..|::.|..:.||:|
  Rat   380 STDNLMDDIERAVDDGVNTFKVLTRDKRLVPGGGATEIELAKQITSYGETCPGLEQYAIKKFAEA 444

  Fly   451 LEVIPSTLAENAGLNPIATVTELRNRHAQGEKNAGINVRK--GAITDIFAENVVQPLLVSISSIT 513
            .|.||..||||:|:.....:::|.:.|.:|.||.|:::..  .|:.|:...:::...|....:|.
  Rat   445 FEAIPRALAENSGVKANEVISKLYSVHQEGNKNVGLDIEAEVPAVKDMLEASILDTYLGKYWAIK 509

  Fly   514 LATETIRSILKIDDIV 529
            |||....::|::|.|:
  Rat   510 LATNAAVTVLRVDQII 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT4	NP_609579.1	TCP1_delta	18..531	CDD:239454	151/519 (29%)
Cct8	NP_001099367.2	chap_CCT_theta	10..539	CDD:274087	156/532 (29%)