Protein Alignment CCT4 and CCT5

DIOPT Version :10

• Sequence 1: NP_609579.1
• Gene: CCT4 / 34674
• FlyBaseID: FBgn0032444
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_036205.1
• Gene: CCT5 / 22948
• HGNCID: 1618
• Length: 541
• Species: Homo sapiens
• Alignment Length: 510
• Identity: 213/510 - (41%)
• Similarity: 312/510 - (61%)
• Gaps: 22/510 - (4%)

  Fly    29 SNIQAAKAVSDAIRTSLGPRGMDKMIQAGNGEVSITNDGATILKQMNVLHPAAKMLVELSRAQDV 93
            |:|.|||||::.:||||||.|:|||:...:|:|::||||||||..|:|.|..||::||||::||.
Human    36 SHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSMMDVDHQIAKLMVELSKSQDD 100

  Fly    94 AAGDGTTSVVVIAGALLEACEKLLQKGLHPTAISDSFQRCSNKAVEILKQMSTPIELD--DRETL 156
            ..|||||.|||:||||||..|:||.:|:||..|:|.:::.:..|:|.|.::|..:.:|  |.|.|
Human   101 EIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARVAIEHLDKISDSVLVDIKDTEPL 165

  Fly   157 IKSASTSLNSKVVSQQSSLLAPIAVDAVLKVTDPGKETSVDLKNIKVISSLGGTVEDTELVDGLV 221
            |::|.|:|.||||:.....:|.|||:|||.|.|. :...||.:.|||...:||.:|||:|:.|::
Human   166 IQTAKTTLGSKVVNSCHRQMAEIAVNAVLTVADM-ERRDVDFELIKVEGKVGGRLEDTKLIKGVI 229

  Fly   222 FTCRSAGSNAPKRIEKAKIGLIQFCISAPKTDMDHNV---IVSDYAAMDRVLKEERSYILNIVKQ 283
            .....:....||::|.|||.::......||....|.:   .|.||.|:.:..||:   ...:::|
Human   230 VDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEK---FEEMIQQ 291

  Fly   284 IKKSGCNVLLVQKSILRDAVSDLAQHFLDKIKCMVVKDVEREDIEFVCKTLHCRPIASLDHFTAE 348
            ||::|.|:.:.|...     .|.|.|.|.:.....|:.|...:||.:......|.:......|||
Human   292 IKETGANLAICQWGF-----DDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAE 351

  Fly   349 NLSSADLVEEVASGT--NKFVKITGIQNMGRTVSIICRGSNKLVLEEAARSLHDALCVVRCLVKL 411
            .|..|.||:|::.||  :|.:.|...:| .|.|:|..||.||:::|||.|||||||||:|.|::.
Human   352 KLGFAGLVQEISFGTTKDKMLVIEQCKN-SRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRD 415

  Fly   412 RAQIVGGGAPEIEMALQLAALAQTVEGVDAYCFRAFADALEVIPSTLAENAGLNPIATVTELRNR 476
            ...:.||||.||..||.::..|.....::.|..|||||||||||..|:||:|:|||.|:||:|.|
Human   416 NRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRAR 480

  Fly   477 HAQGEKNAGINV---RKGAITDIFAENVVQPLLVSISSITLATETIRSILKIDDI 528
            ..: |.|..:.:   .||. .|:..::|::.|:.....|:|||:.:|.|||||||
Human   481 QVK-EMNPALGIDCLHKGT-NDMKQQHVIETLIGKKQQISLATQMVRMILKIDDI 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT4	NP_609579.1	TCP1_delta	18..531	CDD:239454	213/510 (42%)
CCT5	NP_036205.1	TCP1_epsilon	10..535	CDD:239455	213/510 (42%)