Protein Alignment CCT4 and Tcp1

DIOPT Version :9

• Sequence 1: NP_609579.1
• Gene: CCT4 / 34674
• FlyBaseID: FBgn0032444
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_038714.2
• Gene: Tcp1 / 21454
• MGIID: 98535
• Length: 556
• Species: Mus musculus
• Alignment Length: 533
• Identity: 168/533 - (31%)
• Similarity: 285/533 - (53%)
• Gaps: 29/533 - (5%)

  Fly    17 FKDKSKPTDVRLSNIQAAKAVSDAIRTSLGPRGMDKMIQAGNGEVSITNDGATILKQMNVLHPAA 81
            |.|:|....||..|:.||.::::.:::|.||.|:|||:....|:|:||||||||||.:.|.||||
Mouse     8 FGDRSTGEAVRSQNVMAAASIANIVKSSFGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAA 72

  Fly    82 KMLVELSRAQDVAAGDGTTSVVVIAGALLEACEKLLQKGLHPTAISDSFQRCSNKAVEILKQMST 146
            |:|.||:..||...||||||||:||..||:..::|:::.:|||::...::....:||..:.: :.
Mouse    73 KVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINE-NL 136

  Fly   147 PIELDD--RETLIKSASTSLNSKVVSQQSSLLAPIAVDAVL--KVTDPGKETSVDLKNIKVISSL 207
            .|..|:  |:.||.:|.||::||::.......|.:.|||||  |.||...:....:.::.::.:.
Mouse   137 IINTDELGRDCLINAAKTSMSSKIIGINGDYFANMVVDAVLAVKYTDARGQPRYPVNSVNILKAH 201

  Fly   208 GGTVEDTELVDGLVFTCRSAGSNAPKRIEKAKIGLIQFCISAPKTDMDHNVIVSDYAAMDRVLKE 272
            |.:..::.|::|....|.......||||..|||..:.|.:...|..:...|:::|...:|::.:.
Mouse   202 GRSQIESMLINGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQR 266

  Fly   273 ERSYILNIVKQIKKSGCNVLLVQKSILRDAVSDLAQHFLDKIKCMVVKDVEREDIEFVCKTLHCR 337
            |.......:::|..:|.||:|.     ...:.|:...:..:...|.|:.|.:.|::.|.|.....
Mouse   267 ESDITKERIQKILATGANVILT-----TGGIDDMYLKYFVEAGAMAVRRVLKRDLKHVAKASGAS 326

  Fly   338 PIASLDHFTAEN------LSSADLV--EEVASGTNKFVKITGIQNMGRTVSIICRGSNKLVLEEA 394
            .:::|.:...|.      |..|:.|  |.:.......:|.|..:.   :.|||.||:|..:.:|.
Mouse   327 ILSTLANLEGEETFEVTMLGQAEEVVQERICDDELILIKNTKART---SASIILRGANDFMCDEM 388

  Fly   395 ARSLHDALCVVRCLVKLRAQIVGGGAPEIEMALQLAALAQTVEGVDAYCFRAFADALEVIPSTLA 459
            .||||||||||:.:::|::.:.||||.|..:::.|...|.::...:......||.:|.|||:|||
Mouse   389 ERSLHDALCVVKRVLELKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLA 453

  Fly   460 ENAGLNPIATVTELRNRHAQGEKN--------AGINVRKGAITDIFAENVVQPLLVSISSITLAT 516
            .||..:....|.:||..|.:.:.|        .|:::..|...|.....|.:|.:|.:.|:..||
Mouse   454 VNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLVHGKPRDNKQAGVFEPTIVKVKSLKFAT 518

  Fly   517 ETIRSILKIDDIV 529
            |...:||:|||::
Mouse   519 EAAITILRIDDLI 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT4	NP_609579.1	TCP1_delta	18..531	CDD:239454	167/532 (31%)
		Cpn60_TCP1	37..529	CDD:278544	160/511 (31%)
Tcp1	NP_038714.2	chap_CCT_alpha	5..540	CDD:274081	168/533 (32%)
		TCP1_alpha	9..535	CDD:239451	167/532 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60896
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820