Protein Alignment CCT4 and CCT6B

DIOPT Version :9

• Sequence 1: NP_609579.1
• Gene: CCT4 / 34674
• FlyBaseID: FBgn0032444
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_006575.2
• Gene: CCT6B / 10693
• HGNCID: 1621
• Length: 530
• Species: Homo sapiens
• Alignment Length: 534
• Identity: 158/534 - (29%)
• Similarity: 282/534 - (52%)
• Gaps: 35/534 - (6%)

  Fly    15 KAFKDKSKPTDVRLS---NIQAAKAVSDAIRTSLGPRGMDKMIQAGNGEVSITNDGATILKQMNV 76
            ||...|::....|.:   ||.||:.:.|.:||:|||:|..||:.:|.|::.:|.||..:|.:|.:
Human     5 KAVNSKAEVARARAALAVNICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLDEMQI 69

  Fly    77 LHPAAKMLVELSRAQDVAAGDGTTSVVVIAGALLEACEKLLQKGLHPTAISDSFQRCSNKAVEIL 141
            .||.|.::.:::.|||...||||||.|:|.|.||:..:..:.:||||..|::.|:....||:|:|
Human    70 QHPTASLIAKVATAQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIAEGFEAAKIKALEVL 134

  Fly   142 KQMSTPIELDDRETLIKSASTSLNSKVVSQQSSLLAPIAVDAVLKVTDPGKETSVDLKNIKVISS 206
            :::....|: .|:.|:..|.|||.:||.::.:.:|..:.||:||.|..||  ..:||..::::..
Human   135 EEVKVTKEM-KRKILLDVARTSLQTKVHAELADVLTEVVVDSVLAVRRPG--YPIDLFMVEIMEM 196

  Fly   207 LGGTVEDTELVDGLVFTCRSAGSNAPKRIEKAKIGLIQFCISAPKTDMDHNVIVSDYAAMDRVLK 271
            ......||:|:.|||....:...:..||:|.|.|.:....:...||:::...........::::|
Human   197 KHKLGTDTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEYEKTEVNSGFFYKTAEEKEKLVK 261

  Fly   272 EERSYILNIVKQI---KKSGCN------VLLVQKSILRDAVSDLAQHFLDKIKCMVVKDVEREDI 327
            .||.:|.:.|::|   |...|.      |::.||.|...::..||:|.:     :.::..:|.::
Human   262 AERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPFSLDSLAKHGI-----VALRRAKRRNM 321

  Fly   328 EFVCKTLHCRPIA--SLDHFTAENLSSADLVEEVASGTNKFVKITGIQNMGRTVSIICRGSNKLV 390
            |.:  :|.|..:|  |.:..|.:.|..|.||.|...|..||..|....| ..:|:::.:|.||..
Human   322 ERL--SLACGGMAVNSFEDLTVDCLGHAGLVYEYTLGEEKFTFIEECVN-PCSVTLLVKGPNKHT 383

  Fly   391 LEEAARSLHDALCVVRCLVKLRAQIVGGGAPEIEMALQLAALAQTVEGVDAYCFRAFADALEVIP 455
            |.:...::.|.|..::..::....:.|.||.|:.||..|.....:::|......:||||||.:||
Human   384 LTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAEALVTYKNSIKGRARLGVQAFADALLIIP 448

  Fly   456 STLAENAGLNPIATVTELRNRHAQGEKNAGINVRKG-----AITDIFAENVVQPLLVSISSITLA 515
            ..||:|||.:|..|:.:::..|.:.::..|:::..|     |...::....|:..|:. |...:|
Human   449 KVLAQNAGYDPQETLVKVQAEHVESKQLVGVDLNTGEPMVAADAGVWDNYCVKKQLLH-SCTVIA 512

  Fly   516 TETIRSILKIDDIV 529
            |    :||.:|:|:
Human   513 T----NILLVDEIM 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT4	NP_609579.1	TCP1_delta	18..531	CDD:239454	156/531 (29%)
		Cpn60_TCP1	37..529	CDD:278544	149/507 (29%)
CCT6B	NP_006575.2	chap_CCT_zeta	3..530	CDD:274088	158/534 (30%)
		TCP1_zeta	23..526	CDD:239458	154/516 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D207515at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820