DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pdm2 and Pou5f2

DIOPT Version :9

Sequence 1:	NP_001285877.1	Gene:	pdm2 / 34673	FlyBaseID:	FBgn0004394	Length:	893	Species:	Drosophila melanogaster
Sequence 2:	NP_083591.1	Gene:	Pou5f2 / 75507	MGIID:	1922757	Length:	329	Species:	Mus musculus

Alignment Length:	241	Identity:	84/241 - (34%)
Similarity:	125/241 - (51%)	Gaps:	35/241 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   653 QPQLQQSTPKPTSGLTVASAMAKLEQSPEETTDLE-ELEQFAKTFKQRRIKLGFTQGDVGLAMGK 716
            |...:.:.|.|...|.....:|    .||:.:.:: |:||.||..:|:|:.||::|.|||.|:|.
Mouse    82 QSSSEDTCPGPYIALRYMPNLA----LPEDVSAIQKEMEQLAKELRQKRMTLGYSQADVGFAVGA 142

  Fly   717 LYGNDFSQTTISRFEALNLSFKNMCKLKPLLQKWLEDADSTVAKSGGGVFNINTMTSTLSSTPES 781
            ::|...|||||.||||..||..||.||:|||:.|||:.|.   |:..|:..:           |.
Mouse   143 MFGKVLSQTTICRFEAQQLSLANMWKLRPLLKMWLEEVDE---KNLLGICRM-----------EM 193

  Fly   782 ILGR-RRKKRTSIETTVRTTLEKAFLMNCKPTSEEISQLSERLNMDKEVIRVWFCNRRQKEKRIN 845
            ||.: |:::|.|.|..:.:.|||.||...:||.::||.::.||.:.|::::|||.||.|....
Mouse   194 ILEQARKRRRASRERRIGSNLEKLFLQCPEPTPQQISYIAGRLRLQKDLVQVWFSNRSQMGSW-- 256

  Fly   846 PSLDLD-----SPTGTPLSSHAFGYPPQALNMS---HMQMEGGSGS 883
            |:.|..     ..||:|     |..||....|:   |.......||
Mouse   257 PTNDTSRREDVGATGSP-----FPGPPVCFPMAPGLHFDFPHYEGS 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pdm2	NP_001285877.1	POU	691..755	CDD:197673	35/63 (56%)
pdm2	NP_001285877.1	Homeobox	789..842	CDD:278475	21/52 (40%)
Pou5f2	NP_083591.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..24
		Pou	113..181	CDD:278582	37/67 (55%)
		Homeobox	<214..250	CDD:278475	15/35 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3802
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810