DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pdm2 and Pou5f2

DIOPT Version :9

Sequence 1:	NP_001285877.1	Gene:	pdm2 / 34673	FlyBaseID:	FBgn0004394	Length:	893	Species:	Drosophila melanogaster
Sequence 2:	NP_001075220.2	Gene:	Pou5f2 / 680620	RGDID:	1589456	Length:	335	Species:	Rattus norvegicus

Alignment Length:	244	Identity:	84/244 - (34%)
Similarity:	125/244 - (51%)	Gaps:	43/244 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   653 QPQLQQSTPKPTSGLTVASAMAKLEQSPEETTDLE-ELEQFAKTFKQRRIKLGFTQGDVGLAMGK 716
            |...:.:.|.|...|.....:|    .||:.:.:: |:||.||..:|:|:.||::|.|||.|:|.
  Rat    88 QNSSEDTYPGPYIALRYMPNLA----LPEDVSAIQKEMEQLAKELRQKRMTLGYSQADVGFAVGA 148

  Fly   717 LYGNDFSQTTISRFEALNLSFKNMCKLKPLLQKWLEDADSTVAKSGGGVFNINTMTSTLSSTPES 781
            ::|...|||||.||||..||..||.||:|||:.|||:.|.   |:..|:..:           |.
  Rat   149 MFGKVLSQTTICRFEAQQLSLANMWKLRPLLKMWLEEVDE---KNLLGICRM-----------EM 199

  Fly   782 ILGR-RRKKRTSIETTVRTTLEKAFLMNCKPTSEEISQLSERLNMDKEVIRVWFCNRRQ------ 839
            ||.: |:::|.|.|..:.:.|||.||...:||.::||.::.||.:.|::::|||.||.|
  Rat   200 ILQQARKRRRASRERRIGSNLEKLFLQCPEPTPQQISYIAGRLRLQKDLVQVWFSNRSQMAGWPT 264

  Fly   840 --KEKRINPSLDLDSPTGTPLSSHAFGYPPQALNMS---HMQME--GGS 881
              ..:|.|.     ..||.|     |..||....::   |....  |||
  Rat   265 NDSSQRENV-----GATGAP-----FPGPPVCFPLAPGLHFDFPHYGGS 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pdm2	NP_001285877.1	POU	691..755	CDD:197673	35/63 (56%)
pdm2	NP_001285877.1	Homeobox	789..842	CDD:278475	21/60 (35%)
Pou5f2	NP_001075220.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..24
		Pou	119..187	CDD:395105	37/67 (55%)
		homeodomain	<220..256	CDD:412151	15/35 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910