Protein Alignment pdm2 and pou2f2b

DIOPT Version :10

• Sequence 1: NP_723763.1
• Gene: pdm2 / 34673
• FlyBaseID: FBgn0004394
• Length: 893
• Species: Drosophila melanogaster
• Sequence 2: XP_009290402.2
• Gene: pou2f2b / 557055
• ZFINID: ZDB-GENE-060310-1
• Length: 710
• Species: Danio rerio
• Alignment Length: 584
• Identity: 216/584 - (36%)
• Similarity: 277/584 - (47%)
• Gaps: 129/584 - (22%)

  Fly   356 PHVVPSELEHNHHWHGVVCDANGHATRLLHIAPPRAGPTPLPTHQQPPVGEVLPPNSTSFSTIVD 420
            |.|:|......|.|            ||       ..|..|.:|.    ||      .|:..::|
Zfish     8 PFVLPRTASDLHAW------------RL-------KSPLALRSHS----GE------NSYGRLLD 43

  Fly   421 --PPKEPSIYEQPAPNG--------RHCRPANKVMRHMSNSPTPPSPLRSLS------DCGKSFE 469
              ...:|...|.||.:.        |:...:|..::.|..:|...||..|.|      |||
Zfish    44 YIRMSKPVEVENPAADSPMESTDSERNGSDSNNQVQPMKINPFSISPTLSSSIKAKVEDCG---- 104

  Fly   470 EEELELGENCEMP-QNLSSKRQARELDSELENEVLDLAPPPKRLAEEQEEEKVASVNPPQPVAFA 533
                |:......| |...:..|......:|.. :..|.|..::|..:|.:...|:|.... ||.|
Zfish   105 ----EMSPTTATPAQTALTHTQLMLTGGQLAG-LTALLPAQQQLLLQQAQLLAAAVQQSH-VAHA 163

  Fly   534 PEEM-----------HQALQLQLHSYIEMVRQLAPEA-FPNPNLATQFLLQNSLQALAQFQALQQ 586
            ..:.           .||.|.|.....:..::.|..| .|.|....|..|...:|..|  |.:||
Zfish   164 ANQQQAQQQAQQQANQQAAQQQSQGQSQSTQEQAAAAPVPPPPPPHQLPLSQPIQLTA--QDIQQ 226

  Fly   587 MKQQQREDPLPSYSTPLAKSPLRSPSLSPVPRHSKSQQ--RTPPNSMTANSLGMSSAVMTPNTPS 649
            :.|.|:...:|.::.|       ||:...:|:..:.||  .:.||.:........|.:..|...|
Zfish   227 LLQLQQLVLVPGHTLP-------SPAQFLLPQTQQGQQGLLSTPNLIPLPQQNQGSLLAAPPRLS 284

  Fly   650 MQ-QQPQLQQSTPKPTSGLTVASAMAKLEQSPEETTDLEELEQFAKTFKQRRIKLGFTQGDVGLA 713
            :| |:.::.:|:....:.:|         ..|||.:|||||||||:|||||||||||||||||||
Zfish   285 LQAQREKIAESSLNTVTTVT---------SHPEEPSDLEELEQFARTFKQRRIKLGFTQGDVGLA 340

  Fly   714 MGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLQKWLEDADSTVAKSGGGVFNINTMTSTLSST 778
            ||||||||||||||||||||||||||||||||||:|||.||         ..||:.:.|.::.||
Zfish   341 MGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLTDA---------AFFNVYSETMSMDST 396

  Fly   779 ---------P----ESILGRRRKKRTSIETTVRTTLEKAFLMNCKPTSEEISQLSERLNMDKEVI 830
                     |    |.:.||||||||||||.||..||.:||.|.|||||||..:||:|||:||||
Zfish   397 LPSPSSLSSPSLGFEGLPGRRRKKRTSIETNVRVALEHSFLANQKPTSEEILLISEKLNMEKEVI 461

  Fly   831 RVWFCNRRQKEKRINPSLDLDSPTGTP-------LSSHAFGYPPQALNMSHMQMEGGSGSFCGS 887
            |||||||||||||||||      :.||       .:||.   ||  ....||....|.....||
Zfish   462 RVWFCNRRQKEKRINPS------SATPPLPSQPQPTSHK---PP--CYSPHMMSSQGPRQTVGS 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pdm2	NP_723763.1	PHA03247	<375..675	CDD:223021	71/331 (21%)
		POU	691..755	CDD:197673	60/63 (95%)
		Homeodomain	787..843	CDD:459649	43/55 (78%)
pou2f2b	XP_009290402.2	None