DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pdm2 and pou3f1

DIOPT Version :9

Sequence 1:	NP_001285877.1	Gene:	pdm2 / 34673	FlyBaseID:	FBgn0004394	Length:	893	Species:	Drosophila melanogaster
Sequence 2:	NP_001016504.1	Gene:	pou3f1 / 549258	XenbaseID:	XB-GENE-853354	Length:	375	Species:	Xenopus tropicalis

Alignment Length:	382	Identity:	144/382 - (37%)
Similarity:	187/382 - (48%)	Gaps:	102/382 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   535 EEMHQA-----LQLQLHSYIEMVRQLAPEA-----------FPNPNLATQFLLQNSLQALAQFQA 583
            :.|||.     :|..:|.  |.::.||..|           .|||  |:.:...:.|.|.|:..
Frog    25 DRMHQGTTYREVQKMMHQ--EYLQGLATNAGHPMSLTHHQWLPNP--ASDWGSGSHLGAQAEHG- 84

  Fly   584 LQQMKQQQREDPLPSYSTPLAKSPLRSPSLSPVPRHSKS---QQRTPPNSMTANSLGMSSAVMTP 645
             :...|..|||                  ||....|.:|   .|:||.:...|.|.|.....|:|
Frog    85 -KSGVQSSRED------------------LSSSFHHHRSHLVHQQTPSSHAWAQSGGHHLPPMSP 130

  Fly   646 NTPSMQQQPQL-QQSTPKPTSGLTVASAMA-----------------------------KLEQSP 680
            .:.|  .||.: .||:....:|:....|.:                             ..:.|.
Frog   131 GSNS--HQPLIYSQSSYTNLNGMLGPQASSLHHSMRDPLHDDPGVLDTHVESPPQHLSHHQDHSD 193

  Fly   681 EETTDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKP 745
            |:....::||||||.||||||||||||.|||||:|.||||.||||||.|||||.|||||||||||
Frog   194 EDAPSSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKP 258

  Fly   746 LLQKWLEDADSTVAKSGGGVFNINTMTSTLSSTPESILGRRRKKRTSIETTVRTTLEKAFLMNCK 810
            ||.||||:.|||.    |...|::.:.:.         ||:||||||||..|:..||..||...|
Frog   259 LLNKWLEETDSTT----GSPTNLDKIAAQ---------GRKRKKRTSIEVGVKGALENHFLKCPK 310

  Fly   811 PTSEEISQLSERLNMDKEVIRVWFCNRRQKEKRINPSLDLDSPTGTPLSSHAFGYPP 867
            |::.||:.|::.|.::|||:|||||||||||||:       :|.|.|       :||
Frog   311 PSAHEITSLADSLQLEKEVVRVWFCNRRQKEKRM-------TPAGVP-------HPP 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pdm2	NP_001285877.1	POU	691..755	CDD:197673	54/63 (86%)
pdm2	NP_001285877.1	Homeobox	789..842	CDD:278475	30/52 (58%)
pou3f1	NP_001016504.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..29		1/3 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	56..139		26/106 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	151..200		3/48 (6%)
		POU	194..268	CDD:197673	57/73 (78%)
		Homeobox	289..343	CDD:365835	31/53 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910