DRSC/TRiP Functional Genomics Resources

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Protein Alignment pdm2 and POU5F1

DIOPT Version :9

Sequence 1:NP_001285877.1 Gene:pdm2 / 34673 FlyBaseID:FBgn0004394 Length:893 Species:Drosophila melanogaster
Sequence 2:NP_002692.2 Gene:POU5F1 / 5460 HGNCID:9221 Length:360 Species:Homo sapiens


Alignment Length:242 Identity:107/242 - (44%)
Similarity:145/242 - (59%) Gaps:43/242 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   654 PQ--LQQSTPKPTSGLTVAS-------------------AMAKLEQSPEETTDL----EELEQFA 693
            ||  |:.|.|:..:|:.|.|                   ...||||:|||:.|:    :||||||
Human    86 PQGGLETSQPEGEAGVGVESNSDGASPEPCTVTPGAVKLEKEKLEQNPEESQDIKALQKELEQFA 150

  Fly   694 KTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLQKWLEDADSTV 758
            |..||:||.||:||.||||.:|.|:|..||||||.|||||.|||||||||:||||||:|:||:..
Human   151 KLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKLRPLLQKWVEEADNNE 215

  Fly   759 AKSGGGVFNINTMTSTLSSTPESILGRRRKKRTSIETTVRTTLEKAFLMNCKPTSEEISQLSERL 823
                    |:..:...     |:::..|::||||||..||..||..||...|||.::||.::::|
Human   216 --------NLQEICKA-----ETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQL 267

  Fly   824 NMDKEVIRVWFCNRRQKEKRINPSL----DLDSPTGTPLSSHAFGYP 866
            .::|:|:||||||||||.||.:...    |.:: .|:|.|.....:|
Human   268 GLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEA-AGSPFSGGPVSFP 313

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
pdm2NP_001285877.1 POU 691..755 CDD:197673 46/63 (73%)
Homeobox 789..842 CDD:278475 30/52 (58%)
POU5F1NP_002692.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..52
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 88..114 6/25 (24%)
POU 138..212 CDD:197673 50/73 (68%)
DNA binding. /evidence=ECO:0000250|UniProtKB:P20263 180..186 5/5 (100%)
DNA binding. /evidence=ECO:0000250|UniProtKB:P20263 193..196 2/2 (100%)
Homeobox 233..287 CDD:365835 30/53 (57%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3802
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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