Protein Alignment pdm2 and POU2F2

DIOPT Version :10

• Sequence 1: NP_723763.1
• Gene: pdm2 / 34673
• FlyBaseID: FBgn0004394
• Length: 893
• Species: Drosophila melanogaster
• Sequence 2: XP_047294909.1
• Gene: POU2F2 / 5452
• HGNCID: 9213
• Length: 715
• Species: Homo sapiens
• Alignment Length: 551
• Identity: 211/551 - (38%)
• Similarity: 264/551 - (47%)
• Gaps: 159/551 - (28%)

  Fly   419 VDPPKEPSIYEQPAPNGRHCRPANKVMRHMSNSPTPPS-PLRSLSDCGKS--------------F 468
            :|.|.|.:..|:..|:..|..|.||. ...|.|||.|| .:::....|.|              .
Human    24 LDSPSEHTDTERNGPDTNHQNPQNKT-SPFSVSPTGPSTKIKAEDPSGDSAPAAPLPPQPAQPHL 87

  Fly   469 EEEELEL------GENCEMP---QNLSSKRQARELDSELENEVLDLA------------------ 506
            .:.:|.|      |....||   |.|..:.||:.|.:.::......|
Human    88 PQAQLMLTGSQLAGLTALMPAQQQLLLQQAQAQLLAAAVQQSSAAAAANAAAAAAAASASSSTSS 152

  Fly   507 ----------------------PPPKRLAEEQEEEKVASVNPP--------QPVAFAPEEMHQAL 541
                                  |||:..::           ||        ||:....:::.|.|
Human   153 SSSSSASSSTSQPPASSGGGDLPPPQPASQ-----------PPGTPQLTLSQPIQLTAQDIQQLL 206

  Fly   542 QLQLHSYIEMVRQLAPEAFPNPNLATQFLLQNSLQALAQFQALQQMKQQQREDPLPSYSTPLAKS 606
            |||     ::|  |.|              .:.||..||| .|.|.:|.|
Human   207 QLQ-----QLV--LVP--------------GHHLQPPAQF-LLPQAQQSQ--------------- 234

  Fly   607 PLRSPSLSPVPRHSKSQQRTPPNSMTAN-SLGM-SSAVMTPNTPSMQQQPQLQQSTPKPTSGLTV 669
                |.|.|.|...:..|:|....:|:. ..|: :.||..|..|    .|.|  |.|:|...|..
Human   235 ----PGLLPTPNLFQLPQQTQGALLTSQPRAGLPTQAVTRPTLP----DPHL--SHPQPPKCLEP 289

  Fly   670 ASAMAKLEQSPEETTDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALN 734
            .|       .|||.:|||||||||:||||||||||||||||||||||||||||||||||||||||
Human   290 PS-------HPEEPSDLEELEQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALN 347

  Fly   735 LSFKNMCKLKPLLQKWLEDADSTVAKSGGGVFNINTMTSTLSSTPESILGRRRKKRTSIETTVRT 799
            |||||||||||||:|||.||::....|  .:.:.|.::|. |...:.:.||||||||||||.||.
Human   348 LSFKNMCKLKPLLEKWLNDAETMSVDS--SLPSPNQLSSP-SLGFDGLPGRRRKKRTSIETNVRF 409

  Fly   800 TLEKAFLMNCKPTSEEISQLSERLNMDKEVIRVWFCNRRQKEKRINP---SLDLDSPTGTPLSSH 861
            .|||:||.|.|||||||..::|:|:|:||||||||||||||||||||   :..|.|| |.|.|
Human   410 ALEKSFLANQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEKRINPCSAAPMLPSP-GKPAS-- 471

  Fly   862 AFGYPPQALNMSHM-QMEGGSGSFCGSSISS 891
               |.|      || ..:||:|:...|..||
Human   472 ---YSP------HMVTPQGGAGTLPLSQASS 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pdm2	NP_723763.1	PHA03247	<375..675	CDD:223021	71/329 (22%)
		POU	691..755	CDD:197673	60/63 (95%)
		Homeodomain	787..843	CDD:459649	42/55 (76%)
POU2F2	XP_047294909.1	PRK10263	<187..>315	CDD:236669	56/181 (31%)
		POU	294..368	CDD:197673	68/73 (93%)
		Homeodomain	397..453	CDD:459649	42/55 (76%)