DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment pdm2 and pou3f3b

DIOPT Version :9

Sequence 1:	NP_001285877.1	Gene:	pdm2 / 34673	FlyBaseID:	FBgn0004394	Length:	893	Species:	Drosophila melanogaster
Sequence 2:	NP_958855.2	Gene:	pou3f3b / 30321	ZFINID:	ZDB-GENE-980526-140	Length:	443	Species:	Danio rerio

Alignment Length:	313	Identity:	130/313 - (41%)
Similarity:	161/313 - (51%)	Gaps:	89/313 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   585 QQMKQQQREDPLPSYSTPLAKSPLRSPSLSPVPRHSKSQQRTPPNSMTANSLGMSSAVMTPN-TP 648
            |.:|.....|.|.| .|.|..   |:|.|.|...|             |.:.|.::|...|: |.
Zfish   116 QDVKNNSGRDDLHS-GTALHH---RAPHLGPHQTH-------------AGAWGSTTAAHIPSLTG 163

  Fly   649 SMQQQPQLQQSTPKPTSGLTVASAMA------------------KLE------------------ 677
            |.|||..|..|.|   .|.||...::                  :|:
Zfish   164 SQQQQQSLIYSQP---GGFTVNGMLSPPGSQSLVHPGLVRGDTPELDHSSHHHHHHHQHQHHQQA 225

  Fly   678 ---------QSPEETTDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEAL 733
                     .|.|:|...::||.|||.||||||||||||.|||||:|.||||.||||||.|||||
Zfish   226 HHGVNSHDPHSDEDTPTSDDLEHFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEAL 290

  Fly   734 NLSFKNMCKLKPLLQKWLEDADSTVAKSGGGVFNINTMTSTLSSTPESI-----LGRRRKKRTSI 793
            .|||||||||||||.||||:|||:                  :.:|.||     .||:|||||||
Zfish   291 QLSFKNMCKLKPLLNKWLEEADSS------------------TGSPTSIDKIAAQGRKRKKRTSI 337

  Fly   794 ETTVRTTLEKAFLMNCKPTSEEISQLSERLNMDKEVIRVWFCNRRQKEKRINP 846
            |.:|:..||..||...||:::||:.|::.|.::|||:|||||||||||||:.|
Zfish   338 EVSVKGALESHFLKCPKPSAQEITSLADNLQLEKEVVRVWFCNRRQKEKRMTP 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pdm2	NP_001285877.1	POU	691..755	CDD:197673	53/63 (84%)
pdm2	NP_001285877.1	Homeobox	789..842	CDD:278475	30/52 (58%)
pou3f3b	NP_958855.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	21..40
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	100..150		13/50 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	182..244		4/61 (7%)
		POU	238..312	CDD:197673	57/73 (78%)
		Homeobox	333..386	CDD:278475	30/52 (58%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3802
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810