Protein Alignment pdm2 and Pou6f2

DIOPT Version :10

• Sequence 1: NP_723763.1
• Gene: pdm2 / 34673
• FlyBaseID: FBgn0004394
• Length: 893
• Species: Drosophila melanogaster
• Sequence 2: XP_036013870.1
• Gene: Pou6f2 / 218030
• MGIID: 2443631
• Length: 728
• Species: Mus musculus
• Alignment Length: 610
• Identity: 150/610 - (24%)
• Similarity: 232/610 - (38%)
• Gaps: 179/610 - (29%)

  Fly   326 QLKHQQLRDVEEVLQEQEQDEEQEHETLRKP---HVVPSELEHNHHWHGVVCDANGHATRLLHIA 387
            ||:..||:..::..|:|:|.::|:.:....|   |..|:..                       |
Mouse   210 QLQQLQLQQQQQQQQQQQQQQQQQQQPPPPPTSQHPQPASQ-----------------------A 251

  Fly   388 PPRAGPTPLPTHQQPPVGEVLPPNSTSFSTIVDPPKEPSIYEQPAPNGRHCRPANKVMRHMSNSP 452
            ||::.||  |.||.||..:.||.          ||.:.....||..:..|..|.|:.    .|.|
Mouse   252 PPQSQPT--PPHQPPPASQQLPA----------PPAQLQQATQPQQHQPHSHPQNQT----QNQP 300

  Fly   453 TPPSPLRSLSDCGKSFEEEELELGENCEMPQNLSSKRQARELDSELENEVLDLAPP-PKRLAEEQ 516
            :|.                     :....|....|......|.|       .|.|| |.:|.
Mouse   301 SPT---------------------QQSSSPPQKPSPSPGHSLPS-------PLTPPNPLQLV--- 334

  Fly   517 EEEKVASVNPPQPVAFAPEEMHQALQLQLHSYIEMVRQLAPEA----------FPNPNLATQF-- 569
             ...:||.......|.......||....|.|...:..||...|          .|||..::|.
Mouse   335 -NNPLASQAAAAAAAMGSIASSQAFGNALSSLQGVTGQLVTNAQGQIIGTIPLMPNPGPSSQAAS 398

  Fly   570 -------------LLQNSLQALAQFQALQQMKQQQREDPLPSYSTPLAKSPLRSPSLSPVPRHSK 621
                         ||.|     ||.|.:..:...|   .||..:|       :..:|||:    |
Mouse   399 GTQGLQVQPITPQLLTN-----AQGQIIATVIGNQ---ILPVINT-------QGITLSPI----K 444

  Fly   622 SQQRTPPNSMTANSLGMSSAV-----MTPNTPSMQQQPQLQQSTPKPTSGLTVASAMAKLEQSPE 681
            ..|:...:|.|  |:|.:...     :.....:....|..|.|:...:|..:.|.::.:|..:|:
Mouse   445 PGQQLHQSSQT--SVGQAGTQGNLLHLAHGQAATSHSPVRQASSSSSSSSSSSALSVGQLVSNPQ 507

  Fly   682 ------ETTDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTI------------- 727
                  :..:|||:.:|||.||.||:.||.||..||.|:....|..:||:.|
Mouse   508 TAAGEVDGVNLEEIREFAKAFKIRRLSLGLTQTQVGQALSATEGPAYSQSAICRHTILRSHFFLP 572

  Fly   728 -----------------------SRFEALNLSFKNMCKLKPLLQKWLEDADSTVAKSGGGVFNIN 769
                                   :|||.|:::.|:..|:||:|::|:.:|:   |:...|:.|
Mouse   573 QEAQENTIASSLTAKLNPGLLYPARFEKLDITPKSAQKIKPVLERWMAEAE---ARHRAGMQN-- 632

  Fly   770 TMTSTLSSTPESILGRRRKKRTSIETTVRTTLEKAFLMNCKPTSEEISQLSERLNMDKEVIRVWF 834
             :|..:.|.|    .::||:|||........|...|..|..|:.:|:::::|:||.|:||:||||
Mouse   633 -LTEFIGSEP----SKKRKRRTSFTPQALEILNAHFEKNTHPSGQEMTEIAEKLNYDREVVRVWF 692

  Fly   835 CNRRQKEKRINPSLDLDSPT-GTPL 858
            ||:||..|.....|....|| ..||
Mouse   693 CNKRQALKNTIKRLKQHEPTSAAPL 717

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pdm2	NP_723763.1	PHA03247	<375..675	CDD:223021	69/330 (21%)
		POU	691..755	CDD:197673	28/99 (28%)
		Homeodomain	787..843	CDD:459649	24/55 (44%)
Pou6f2	XP_036013870.1	Pou	514..623	CDD:473999	31/108 (29%)
		Homeodomain	645..701	CDD:459649	24/55 (44%)