Protein Alignment pdm2 and ceh-18

DIOPT Version :10

• Sequence 1: NP_723763.1
• Gene: pdm2 / 34673
• FlyBaseID: FBgn0004394
• Length: 893
• Species: Drosophila melanogaster
• Sequence 2: NP_741758.1
• Gene: ceh-18 / 180671
• WormBaseID: WBGene00000441
• Length: 542
• Species: Caenorhabditis elegans
• Alignment Length: 542
• Identity: 170/542 - (31%)
• Similarity: 257/542 - (47%)
• Gaps: 147/542 - (27%)

  Fly   468 FEEEELELGENCEMPQNLS------SKRQARELDSEL-ENEVLDLAPPPKRLAEEQEEEKVASVN 525
            |..|..|....|.:.:.:|      |||::|.:...: |:||:    |.:.:.||:|||||
 Worm    10 FLAEVFEANGGCLVTERVSPSLSGASKRKSRPVKRIITEDEVI----PEEEVVEEEEEEKV---- 66

  Fly   526 PPQPVAFAPEEMHQALQLQ-LHSYIEMVRQLA-----------------PEAFPNPN-------- 564
             .||   :.|....|:|:. ..:.:..:||:|                 .|.|.|.|
 Worm    67 -EQP---SEEVTCPAMQVDATDAILASLRQIANNDLSEHCIREDEGNTSAEVFSNGNGEDMEQAG 127

  Fly   565 -LATQFL------LQNSLQALAQFQALQQMKQQQRE--DPLP------SYSTPLAKSPLRSPSLS 614
             ..|..|      ||.:.........|||.....:|  ||.|      ...||:      :..||
 Worm   128 LAGTDLLRRVADMLQGNHNGSLNSHFLQQQFAAFKETVDPTPVSTNGNGLLTPI------TTQLS 186

  Fly   615 PV---------PRHSKSQQRTPP-NSMTANSLGMSSAVMTPNTPSMQQQPQLQQS---TP-KPTS 665
            |:         |........||. ..:.||.||.|::.:. ::|.:...|.|.||   || :||:
 Worm   187 PLFTSTDAFNSPEKLLQAIMTPSLGFLGANGLGASNSGLL-SSPLIAPSPTLLQSLMNTPTQPTA 250

  Fly   666 GLTVASA---------------------MAKLE---QSPEETTDLEELEQFAKTFKQRRIKLGFT 706
            .||...|                     .:::|   .|.::..|:.|||.||:|||::|||.|||
 Worm   251 SLTPKKAENRPPVVSQTLKASKRRLFDDTSRIEAASMSGDDRIDMNELEAFAQTFKKQRIKFGFT 315

  Fly   707 QGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLQKWLEDADSTVAKSGGG------- 764
            |||||:|:||.||.|||||||||||||||||||||||:|||::||  ||..:|..||.
 Worm   316 QGDVGVALGKRYGTDFSQTTISRFEALNLSFKNMCKLRPLLKEWL--ADVEMAIEGGATVTDLID 378

  Fly   765 ---VFNIN------------TMTSTLSS-TPESILGR-----RRKKRTSIETTVRTTLEKAFLMN 808
               :.|.|            ::::::|| |..|:|.|     ||:|||:::...|..|:..|.:|
 Worm   379 KKTIHNGNHHTIHHVDIHETSISNSISSVTASSLLSREQHVKRRRKRTNLDMNQRNALDTFFALN 443

  Fly   809 CKPTSEEISQLSERLNMDKEVIRVWFCNRRQKEKRINPSL--DLDSPTGTPLSSH-----AFGYP 866
            .:|..::::.::..|.:|::|:||||||||||.:|::..:  ::.:|:.:|:..|     |....
 Worm   444 PRPDHDKMTDIANSLELDRDVVRVWFCNRRQKMRRVDEPIEGEMVTPSVSPVFPHFSSMSALEQI 508

  Fly   867 PQALNMSHMQ-----MEGGSGS 883
            .:|..::..|     .:|.|||
 Worm   509 QEAARLASCQASNDDSDGTSGS 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pdm2	NP_723763.1	PHA03247	<375..675	CDD:223021	68/289 (24%)
		POU	691..755	CDD:197673	49/63 (78%)
		Homeodomain	787..843	CDD:459649	22/55 (40%)
ceh-18	NP_741758.1	POU	290..364	CDD:197673	55/75 (73%)
		Homeodomain	422..478	CDD:459649	22/55 (40%)