Protein Alignment pdm2 and Pou2f1

DIOPT Version :10

• Sequence 1: NP_723763.1
• Gene: pdm2 / 34673
• FlyBaseID: FBgn0004394
• Length: 893
• Species: Drosophila melanogaster
• Sequence 2: NP_001094109.1
• Gene: Pou2f1 / 171068
• RGDID: 621689
• Length: 768
• Species: Rattus norvegicus
• Alignment Length: 504
• Identity: 193/504 - (38%)
• Similarity: 254/504 - (50%)
• Gaps: 98/504 - (19%)

  Fly   429 EQPAPNGR--HCRPANKVMRHMSNSPTPPSPL----RSLSDCGKSFEE--EELELGENCEMPQNL 485
            :||.|.|.  ....|...:.|:.......:.|    :||:...||.||  :..:..:..:.|...
  Rat    53 KQPVPVGGAISTAQAQAFLGHLHQVQLAGTSLQAAAQSLNVQSKSSEESGDSQQSSQPSQQPSVQ 117

  Fly   486 SSKRQARELDSELENEVLDLAPPPKRLAEEQEEEKVASVNPPQPVAFAPEEMHQALQLQLHSYIE 550
            |:..|.:.:.:..:...|.|.|..::|..:|.:.:.      |.:|.|.:: |.|  .|.||...
  Rat   118 SAIPQTQLMLAGGQITGLTLTPAQQQLLLQQAQAQA------QLLAAAVQQ-HSA--SQQHSAAG 173

  Fly   551 MVRQLAPEAFPNPNLATQFLLQNSLQALAQFQALQQMKQQQRE-------DPLPSY--------S 600
            .... |..|.|    .||..|...:|.....|.|||::||...       .|..:.        .
  Rat   174 ATIS-ASAATP----MTQIPLSQPIQIAQDLQQLQQLQQQNLNLQQFVLVHPTTNLQPAQFIISQ 233

  Fly   601 TPLAKSPLRSPS--LSPVPRHSKSQQRTPPNSMTANSLGMSSAVMTPNTPS-------MQQQPQL 656
            ||..:..|....  |:.:|:.|::....|..|:|..|        .|.||:       :|..||
  Rat   234 TPQGQQGLLQAQNLLTQLPQQSQANLLQPQPSITLTS--------QPTTPTRTIAATPIQTLPQ- 289

  Fly   657 QQSTPKPTSGLTVASAMAKLEQSPEETTDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGND 721
            .|:|||...           ..|.||.:|||||||||||||||||||||||||||||||||||||
  Rat   290 SQTTPKRID-----------TPSLEEPSDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGND 343

  Fly   722 FSQTTISRFEALNLSFKNMCKLKPLLQKWLEDADSTVAKSGGGVFNINTMTSTLSSTPESI---- 782
            ||||||||||||||||||||||||||:|||.||:             |..:.:.:|:|.::
  Rat   344 FSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAE-------------NLSSDSTASSPSALNSPG 395

  Fly   783 -----LGRRRKKRTSIETTVRTTLEKAFLMNCKPTSEEISQLSERLNMDKEVIRVWFCNRRQKEK 842
                 |.|||||||||||.:|..|||:|:.|.|||||:|:.::|:|||:||||||||||||||||
  Rat   396 LGAEGLNRRRKKRTSIETNIRVALEKSFMENQKPTSEDITLIAEQLNMEKEVIRVWFCNRRQKEK 460

  Fly   843 RINPSLDLDSPTGTPLSSHAFGYPPQALNMSHMQMEGGSGSFCGSSISS 891
            ||||          |.|......|.:|:..|...:...:.|...||.::
  Rat   461 RINP----------PSSGGTSSSPIKAIFPSPTSLVATTPSLVTSSTAT 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pdm2	NP_723763.1	PHA03247	<375..675	CDD:223021	63/277 (23%)
		POU	691..755	CDD:197673	61/63 (97%)
		Homeodomain	787..843	CDD:459649	40/55 (73%)
Pou2f1	NP_001094109.1	POU	303..377	CDD:197673	69/73 (95%)
		Homeodomain	405..461	CDD:459649	40/55 (73%)
		POU2F1_C	475..754	CDD:437368	5/25 (20%)