Protein Alignment pdm2 and pdm3

DIOPT Version :10

• Sequence 1: NP_723763.1
• Gene: pdm2 / 34673
• FlyBaseID: FBgn0004394
• Length: 893
• Species: Drosophila melanogaster
• Sequence 2: XP_061509788.1
• Gene: pdm3 / 1280360
• VectorBaseID: AGAMI1_003138
• Length: 871
• Species: Anopheles gambiae
• Alignment Length: 959
• Identity: 211/959 - (22%)
• Similarity: 314/959 - (32%)
• Gaps: 358/959 - (37%)

  Fly    19 STTATETAAAAATAKAAA-----------------------TAAAAATATM-LLTSPTAATHCLA 59
            |.|:| ||||||.|.|||                       |.|:....:: |.|||......|.
Mosquito   121 SATST-TAAAAAAAVAAAQVHLNGTMQDMINLQKLQSLAQLTGASVLGPSLGLPTSPLLGNSPLN 184

  Fly    60 AATSAAGVNVQITGQGVSATLNDDQLQLPANYAANVGHLNGFNPKDNCPPVPPTSER-AFEGLLR 123
            .:.|....:.|:.|.|.:|.:.....|:|....|:...:.|.   .....:.|||:. |.:.:|.
Mosquito   185 LSLSGQNHSPQVLGLGPAAPIAAAAPQMPQLLLASGQIMQGI---QGAQLLIPTSQGIATQTILT 246

  Fly   124 LPQIQVKQEFMESPPERPSCHPMN---------HQQAPANSALATSCRGKTILNPWYLRPADGIG 179
            :|   |.|:.:.:.........:|         ..||...:|.|.:..|.....|   |.|.|.|
Mosquito   247 IP---VGQQVISNMSSEALLQSLNFNNSLSETLSSQAAQAAAAAAAASGGLFAPP---RDAQGTG 305

  Fly   180 YHNYNSNNNNSGSGEINKDVSQQMTSACGGSDGQTCLPVSYFGMETLASVKQRQKSLPDFLIPLH 244
                      ||.|.::   :|.:.||.|.
Mosquito   306 ----------SGGGLLS---TQLLGSAAGA----------------------------------- 322

  Fly   245 EIMFQQQHHYQQRTMGTLINSLPPGLVGYPPQKTETFKSLTPPKALQHHQNNQNHQIPQNHTGDH 309
                    |.||.:                            ||.| |:.|:.:|.  .:|.||.
Mosquito   323 --------HAQQHS----------------------------PKGL-HYANHHHHH--HHHHGDV 348

  Fly   310 SFVRHFHERDRLIREHQLKHQQLRDVEEVLQEQEQDEEQEHETLRKPHVVPSELEHNHHWHGVVC 374
            .|..:.....          ........|:..........|:|.|:.|:.|
Mosquito   349 KFKPNASSTS----------SSSCSSSSVVVSGASCMSSVHDTHRQQHLPP-------------- 389

  Fly   375 DANGHATRLLHIAPPRAGPTPLPTHQQPPVGEVLPPNSTSFSTIVDPPKEPSIYEQPAPNGRHCR 439
               ||:     ::...|....| .|:....|.:.|..........|.||..|:.....|...|.|
Mosquito   390 ---GHS-----LSSASASSNTL-DHRSAVAGRMTPDMHRVKLQAGDSPKRISLVASSPPVSTHSR 445

  Fly   440 PANKVMRHMSNSPTPPSPLRSLSDCGKSFEEEELELGENCEMPQNLSSKRQARELDSELENEVLD 504
            ||                  |.:.|..|..::.:.|            ||.
Mosquito   446 PA------------------SYASCSSSPYDKSMTL------------KRA-------------- 466

  Fly   505 LAPPPKRLAEEQEEEKVASVNPPQPVAFAPEEMHQA---LQLQLHSYIEMVRQLAP---EAFPNP 563
            |:||             |::|...|.:.:....|.:   ||:.:||.|......:|   .|....
Mosquito   467 LSPP-------------ATLNCTTPSSSSSGSGHSSNGHLQVNVHSAISAASPRSPSDASAINRL 518

  Fly   564 NLATQFLLQNSLQALAQFQALQQMKQQQREDPLPSYS-----------TPLAK-SPLRSP--SLS 614
            .|.|..:                       |.|||.|           .||.| .|...|  |:|
Mosquito   519 GLPTGGV-----------------------DLLPSKSKLSPGGSSSSGLPLTKDQPSSHPHASVS 560

  Fly   615 PVPRHSKS------------------------QQRTPPNSMTANSLGMSSAVMTPNT--PSMQQQ 653
            |:..||.|                        ||:....:.:|:.|.:..    |:|  .|....
Mosquito   561 PLHHHSSSGPSAPGSTGRPGSCDLELIEQHQHQQQQHHRAPSADDLELEK----PSTVGSSSGTV 621

  Fly   654 PQLQQ-------STPKP---TSGLT-----------VASAMAKLEQSPEETT------------D 685
            .|||:       |||.|   .:|.|           .||....||:.|.|.|            |
Mosquito   622 HQLQKRSHHSAASTPPPKLSPAGSTGRLSHSDDDDDDASNHEFLEEHPNELTINQTNCNVVDGID 686

  Fly   686 LEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTI-------------------SRFE 731
            |:::::|||.||.||:.||.||..||.|:....|..:||:.|                   ..||
Mosquito   687 LDDIKEFAKAFKLRRLSLGLTQTQVGQALSVTEGPAYSQSAICSALAAQMYCAAQLSSQQQQMFE 751

  Fly   732 ALNLSFKNMCKLKPLLQKWLEDAD---STVAKSGGGVFNINTMTSTLSSTPESILGRRRKKRTSI 793
            .|:::.|:..|:||:|::|:::|:   |:..|||.     |.:...:...|    .::||:|||.
Mosquito   752 KLDITPKSAQKIKPVLERWMKEAEESHSSRYKSGQ-----NHVPDFIGVEP----SKKRKRRTSF 807

  Fly   794 ETTVRTTLEKAFLMNCKPTSEEISQLSERLNMDKEVIRVWFCNRRQKEK 842
            .......|...|..|..|:..||:.|:.:|..::||||:||||:||..|
Mosquito   808 TPQALELLNGHFERNTHPSGTEITGLAHQLGYEREVIRIWFCNKRQALK 856

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pdm2	NP_723763.1	PHA03247	<375..675	CDD:223021	72/366 (20%)
		POU	691..755	CDD:197673	27/82 (33%)
		Homeodomain	787..843	CDD:459649	24/56 (43%)
pdm3	XP_061509788.1	None