Protein Alignment pdm2 and POU6F2

DIOPT Version :9

• Sequence 1: NP_001285877.1
• Gene: pdm2 / 34673
• FlyBaseID: FBgn0004394
• Length: 893
• Species: Drosophila melanogaster
• Sequence 2: NP_001357888.1
• Gene: POU6F2 / 11281
• HGNCID: 21694
• Length: 720
• Species: Homo sapiens
• Alignment Length: 600
• Identity: 146/600 - (24%)
• Similarity: 241/600 - (40%)
• Gaps: 165/600 - (27%)

  Fly   329 HQQLRDVEEVLQEQEQDEEQEHETLRKPHVVPSELEHNHHWHGVVCDANGHATRLLHIAPPRAGP 393
            :.||:.::..||:|:|.::|:.......|..|:..                       ||.::..
Human   205 NSQLQQLQLQLQQQQQQQQQQPPPSTNQHPQPAPQ-----------------------APSQSQQ 246

  Fly   394 TPL-PT-HQQPPVGEVLPPNSTSFSTIVDPPKEPSIY------EQPAPNGRHCRPANKVMR---H 447
            .|| || .||||.....||..||.......|::...:      .||:|..:...|..|..:   |
Human   247 QPLQPTPPQQPPPASQQPPAPTSQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQSPGH 311

  Fly   448 MSNSP-TPPSPLRSLSDCGKSFEEEELELGENCEMPQNLSSKRQARELDS-----ELENEVLDLA 506
            ...|| |||:||:.:::                  |....:...|..:.|     ...|.:..|.
Human   312 GLPSPLTPPNPLQLVNN------------------PLASQAAAAAAAMSSIASSQAFGNALSSLQ 358

  Fly   507 PPPKRLAEEQEEEKVASV----NP-PQPVAFAPEEMHQALQLQLHSYIEMVRQLAPEAFPNPNLA 566
            ....:|....:.:.:.::    || |...|.:..   |.||:|         .:.|:...|
Human   359 GVTGQLVTNAQGQIIGTIPLMPNPGPSSQAASGT---QGLQVQ---------PITPQLLTN---- 407

  Fly   567 TQFLLQNSLQALAQFQALQQMKQQQREDPLPSYSTPLAKSPLRSPSLSPVPRHSKSQQRTPPNSM 631
                        ||.|.:..:...|   .||..:|       :..:|||:   ...||...|:.
Human   408 ------------AQGQIIATVIGNQ---ILPVINT-------QGITLSPI---KPGQQLHQPSQ- 446

  Fly   632 TANSLGMSSAV-----MTPNTPSMQQQPQLQQSTPKPTSGLTVASAMAKLEQSPE------ETTD 685
              .|:|.:::.     :..:..||.|.|..|.|:...:|..:.|.::.:|..:|:      :..:
Human   447 --TSVGQAASQGNLLHLAHSQASMSQSPVRQASSSSSSSSSSSALSVGQLVSNPQTAAGEVDGVN 509

  Fly   686 LEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTI----------------------- 727
            |||:.:|||.||.||:.||.||..||.|:....|..:||:.|
Human   510 LEEIREFAKAFKIRRLSLGLTQTQVGQALSATEGPAYSQSAICRHTILRSHFFLPQEAQENTIAS 574

  Fly   728 -------------SRFEALNLSFKNMCKLKPLLQKWLEDADSTVAKSGGGVFNINTMTSTLSSTP 779
                         :|||.|:::.|:..|:||:|::|:.:|:   |:...|:.|   :|..:.|.|
Human   575 SLTAKLNPGLLYPARFEKLDITPKSAQKIKPVLERWMAEAE---ARHRAGMQN---LTEFIGSEP 633

  Fly   780 ESILGRRRKKRTSIETTVRTTLEKAFLMNCKPTSEEISQLSERLNMDKEVIRVWFCNRRQKEKRI 844
                .::||:|||........|...|..|..|:.:|:::::|:||.|:||:||||||:||..|..
Human   634 ----SKKRKRRTSFTPQALEILNAHFEKNTHPSGQEMTEIAEKLNYDREVVRVWFCNKRQALKNT 694

  Fly   845 NPSLDLDSP-TGTPL 858
            ...|....| |..||
Human   695 IKRLKQHEPATAVPL 709

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pdm2	NP_001285877.1	POU	691..755	CDD:197673	28/99 (28%)
		Homeobox	789..842	CDD:278475	22/52 (42%)
POU6F2	NP_001357888.1	Pou	506..615	CDD:389985	31/108 (29%)
		Homeobox	639..693	CDD:365835	22/53 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3802
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810