Protein Alignment pdm2 and pou5f3.2

DIOPT Version :10

• Sequence 1: NP_723763.1
• Gene: pdm2 / 34673
• FlyBaseID: FBgn0004394
• Length: 893
• Species: Drosophila melanogaster
• Sequence 2: NP_001123406.1
• Gene: pou5f3.2 / 100170181
• XenbaseID: XB-GENE-919841
• Length: 459
• Species: Xenopus tropicalis
• Alignment Length: 421
• Identity: 130/421 - (30%)
• Similarity: 189/421 - (44%)
• Gaps: 91/421 - (21%)

  Fly   527 PQPVAFA-----PEEMHQALQ-----------------LQLHSYIEMVRQLAPEAFPNPNLATQF 569
            |||.:||     .|.....:|                 ...|..:|..:|..|...|:|   |..
 Frog    34 PQPFSFAFSTLKSENGDSGVQGMGDCSAPVMPWNSMASFDHHGQVETNQQGNPIRAPSP---TPT 95

  Fly   570 LLQNSLQALAQFQALQQMKQQQREDPLPSYSTP----------LAKSPL---------RSPSLSP 615
            |..:.::..   :.:........|.|.|.|.:|          ...||.         .|.|.:|
 Frog    96 LSDSRIKVK---EEVAHETDSGEESPEPKYPSPPNPSLYYPNTWTGSPFWQVNPTAGNNSNSTNP 157

  Fly   616 VPRHSKSQQRTPPNSMTANSLGMSSAVMTPNTP------SMQQQ----------PQLQQSTPKPT 664
            :|    ||......|:..|:...:.|..:||||      ||:..          ...:::|..|.
 Frog   158 MP----SQTLVKNGSLPGNTTYPTPANQSPNTPVDCVVSSMESSRCSSANSSNGAINERATTIPN 218

  Fly   665 SGLTVASAMAKLEQSPEETTDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISR 729
            .|:......:..|   ||.....|:|||||..|.:|:.:|:||.|||.|:|.|||..||||||.|
 Frog   219 GGMVDGGQSSDNE---EEVPSESEMEQFAKDLKHKRVSMGYTQADVGYALGVLYGKMFSQTTICR 280

  Fly   730 FEALNLSFKNMCKLKPLLQKWLEDADSTVAKSGGGVFNINTMTSTLSSTPESILGRRRKKRTSIE 794
            ||:|.|||||||:|||.|::||.:|:           |.:.:...::........|:||:||:||
 Frog   281 FESLQLSFKNMCQLKPFLERWLVEAE-----------NNDNLQELINREQVIAQTRKRKRRTNIE 334

  Fly   795 TTVRTTLEKAFLMNCKPTSEEISQLSERLNMDKEVIRVWFCNRRQKEKRIN-PSLDLDSPTG--- 855
            ..|:.|||..|:...||.::|:.|:::.|||||:|:||||||||||.||.. |::|.:...|
 Frog   335 NIVKGTLESYFMKCSKPGAQEMVQIAKELNMDKDVVRVWFCNRRQKGKRQGMPTVDENDGEGYDV 399

  Fly   856 -----TPLSSHAFGYPPQALNMSHMQMEGGS 881
                 :|...| :..|....:..:|....||
 Frog   400 GQTMASPPVGH-YSLPQVVTSQGYMAAPLGS 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pdm2	NP_723763.1	PHA03247	<375..675	CDD:223021	40/204 (20%)
		POU	691..755	CDD:197673	40/63 (63%)
		Homeodomain	787..843	CDD:459649	31/55 (56%)
pou5f3.2	NP_001123406.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	78..131		12/58 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	216..238		5/24 (21%)
		Pou	235..306	CDD:459692	42/70 (60%)
		Homeodomain	327..383	CDD:459649	31/55 (56%)