Protein Alignment Nepl7 and Nep1

DIOPT Version :9

• Sequence 1: NP_001285879.1
• Gene: Nepl7 / 34671
• FlyBaseID: FBgn0032442
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_001284925.1
• Gene: Nep1 / 31547
• FlyBaseID: FBgn0029843
• Length: 849
• Species: Drosophila melanogaster
• Alignment Length: 712
• Identity: 190/712 - (26%)
• Similarity: 310/712 - (43%)
• Gaps: 133/712 - (18%)

  Fly    44 LLSTMNRTIDPCENFYEFSCGGWKKADLVPEQARNTSFLNAIQHKIDEQIQGFLQNATKRELEDL 108
            |||.|:...||||:|::::||.|.|...:||...:.|....    :.:|.|..|:...:..:::
  Fly   185 LLSAMDLNSDPCEDFFQYACGTWNKMHPIPEDRSSISTFEV----LSDQQQVILRAVLEEPIDE- 244

  Fly   109 GVNGTTSAEIKAKQFYASCVEMKANLSLG----YQYFMEHDGDRLKERNATYDW----------- 158
               ....|.||||.|:.||:::.....:|    .|......|..:.|||    |
  Fly   245 ---RDNKATIKAKTFFKSCMDIPQIRKIGTGRLKQVLQSLGGWPVIERN----WSPPADLSVERL 302

  Fly   159 ---------------MYINFMSKYDIYPLLAL-KVHYSTSSRKFDILLTLPSKVLAGFSEEQLKN 207
                           :|:....|.....:|.: ::.|:..||.:             :.:|...|
  Fly   303 MGQLRLNYSEPVMIELYVGADDKNSSVNILQMDQLQYALPSRDY-------------YLKESSAN 354

  Fly   208 MTREF-----------GLD-----SSAEKVKQFVENFNNLTQFERNLVSLAKSRNETEQLNFKEF 256
            ..|.:           |.|     :..|||..|.....|        |||.::......|.:::.
  Fly   355 DRRAYHRYMTQVALLLGADPATAAAELEKVVLFETQLVN--------VSLPEADRHDTSLVYRKM 411

  Fly   257 LVKHKHD---RLNWTRFFELAFNGS---QESHWPVLNQLDNINDLVFFLEQTNLETLKGYI---- 311
            |:....:   .:.|..:.:.|....   ||....|...|..:.::...|..|:...:..|:
  Fly   412 LLPELQELVPEVQWQEYLQAALGPGIPLQEDEPLVTYGLHYLTEMGKILAHTDRRVVHNYMLWRL 476

  Fly   312 -----------KMRELVKF----YGLWKTQTKTGGVQSECRSLSETYFNYALLPWFIGKVFDKER 361
                       ..||.|:|    .|:...:|:    .|:|...:......|:...||...|::|.
  Fly   477 VMSLMSHMIDEYQRERVEFRKILMGIQSERTR----WSQCVEWTNKKLGVAVGALFIRDNFNQES 537

  Fly   362 RADILSVAKDIKDTFYDLLDHHTWLDEDTRSQAKTKLASMDILVGYTDDLQHREVIDGVYSDINM 426
            :...|.:...|:..|.:||..:.|:|::||:.||.|..||:..:||.:.|.:...::..|  :|:
  Fly   538 KEVALEMIHTIRAAFNELLAENDWMDDETRAVAKEKADSMNERIGYPELLTNATELEQEY--VNL 600

  Fly   427 T---GNWFEN-LCILE-GSRARIRL--RSVDKALIPLLMPTRTVNAYYADFLNLAFITIGMAQWP 484
            |   .|:..| |.||: .|...:||  :.|||.  ........|||:|....|......|:.|..
  Fly   601 TIVPDNFINNVLSILQWESEKMLRLLRQPVDKE--KWTTEPAVVNAFYNPNKNDIVFPAGILQPL 663

  Fly   485 FYHIDFPDVLKYAGVGNIIGHEMAHGFDSYCYQYNYDGKKTNWWSSASLRNFKERYRCLESQYNK 549
            ||...||..|.|.|:|.:||||:.||||....|::.:|....||::|::..|:||.:|:..||::
  Fly   664 FYSQHFPKSLNYGGIGVVIGHEITHGFDDKGRQFDKEGNMMQWWNNATIEAFRERTQCVIDQYSR 728

  Fly   550 FILMGVQ--TNGSLTSGDNIADNVGTRMAYYAFKRKTGDKAW-----LEKPLRGVNFNNKQLFFV 607
            :.:..|.  .:|.:|.|:|||||.|.:.|:.|:|:      |     .|:.|.|:|..:.||||:
  Fly   729 YKINEVDMFMDGRMTQGENIADNGGLKQAFRAYKK------WETLHGREQQLPGLNMTHDQLFFL 787

  Fly   608 KFAQTWCNGKDNGDKLRRLKTDVHAYDEFRVQGTLSNMPEFSEAFNCKLGTEMNPLKKCVVW 669
            .:||.||......|.|.::::.||:....||.|.|||..:|:.|:.|.||:.|||.:||.||
  Fly   788 NYAQIWCGSMRPEDALTKIRSAVHSPGFVRVLGPLSNSRDFASAYKCPLGSTMNPAEKCSVW 849

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl7	NP_001285879.1	PepO	43..669	CDD:226118	188/710 (26%)
		M13	52..666	CDD:189000	182/699 (26%)
Nep1	NP_001284925.1	M13	194..847	CDD:189000	183/699 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469685
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850