Protein Alignment Nepl7 and Kel

DIOPT Version :9

• Sequence 1: NP_001285879.1
• Gene: Nepl7 / 34671
• FlyBaseID: FBgn0032442
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_001178540.1
• Gene: Kel / 297025
• RGDID: 1565470
• Length: 713
• Species: Rattus norvegicus
• Alignment Length: 719
• Identity: 173/719 - (24%)
• Similarity: 291/719 - (40%)
• Gaps: 154/719 - (21%)

  Fly    35 EMLEDYGRFLLSTMNRTIDPCENFYEFSCGGWKKADLVPEQARNTSFLNAIQHKIDEQIQGFLQN 99
            |::..|    |::.||:..||.:|:.|:|          |:|..||  |:.|...:|.     ::
  Rat    65 ELVNHY----LASGNRSAAPCTDFFSFAC----------EKANGTS--NSFQALAEEN-----KS 108

  Fly   100 ATKRELEDLGVNGTTSAEIKAKQFYASCVEMKANLSLG----YQYFMEHDGDRLKERNATYDWMY 160
            ...:.||..|.....|.|.||.|||.||::..|..:.|    .|...|..|     .|.:.:|.:
  Rat   109 RLWKLLEAPGSWHLESGEEKAFQFYNSCMDTDAIEASGTGPLVQIIKELGG-----WNISGNWTF 168

  Fly   161 INF-------MSKYDIYPLLALKVH----------YSTSSRKFDILL--TLPSKVLAGFSEEQLK 206
            .:|       ||:|..:|.....:|          ......:|||||  ....||.|....|.:.
  Rat   169 FDFNQNLRLLMSQYGHFPFFRAYLHPHPAPPHTPIIQIDQPEFDILLQQDQEQKVYAQILREYVT 233

  Fly   207 NMTREFG--LDSSAEKVKQF----VENFNNLTQFERNLVSLAKSRNETEQLNFKEFLV------K 259
            .:.| .|  |.|:.::.:|.    :...:.|.||.|        ..:.:|...|.|.|      :
  Rat   234 YLNR-LGTLLGSNPQEAQQHASWSIVFTSRLFQFLR--------PQQQQQAQDKLFHVVTIDALQ 289

  Fly   260 HKHDRLNWTR-----FFELAFNGSQESHWPVLNQLDNINDLVFFLEQTNLETLKGYIKMRELVKF 319
            .....::|..     |..::.:.||......|:.|.|::.||          .:|.:...|:::.
  Rat   290 EMAPAIDWLSCLQAIFTPMSLSPSQTLQVHDLDYLRNMSQLV----------EEGLLNHSEIIQS 344

  Fly   320 Y---GL---------WKTQTKTGGVQSECRSLSE------------------TYFNYALLPWFIG 354
            |   ||         .|.|.....:..:.|.|.|                  ::|...|...|:.
  Rat   345 YMILGLVDTLSPALATKFQEARRELTQKLRKLKERPPLPAYPRWMKCVEQTGSFFEPTLAALFVH 409

  Fly   355 KVFDKERRADILSVAKDIKDTFYDLLDHHTWLDEDTRSQAKTKLASMDILVGYTDDLQHREVIDG 419
            :.|....|:..:.:..:|||.....|...:|:.|:||.:|..||..:.:.:|........|:...
  Rat   410 EAFGPSIRSAAMELFAEIKDAVIVRLKKLSWISEETRKEALNKLTQLQVEMGAPKRALKTEMAKQ 474

  Fly   420 VYSDINMTGNWFENL--CI--LEGSRARIRLRSVDKALIPLLMP---------TRTVNAYYADFL 471
            .||||.:..::.::.  |:  |:|.:.|           ..|.|         ..:|:|||:...
  Rat   475 EYSDIQLGPSFLQSFLSCVRSLQGRKVR-----------SFLQPFPYHRWQKSPWSVSAYYSVPD 528

  Fly   472 NLAFITIGMAQWPFYHIDFPDVLKYAGVGNIIGHEMAHGFDSYCYQYNYDGKKTNWWSSASLRNF 536
            ::.....|:.|.||:|..:|..:.:..||:|:.|::.|.|    :|:...|    ...:...|..
  Rat   529 HVVVFPAGLLQPPFFHPGYPRAVNFGAVGSIMAHKLLHIF----FQFLLPG----GCPACDTRAL 585

  Fly   537 KERYRCLESQYNKFILMGVQT-NGSLTSGDNIADNVGTRMAYYAFKRKTGDKAWLEKPLRGVNFN 600
            :|...|||.:|..|.|..:.: |||.|..:|.||..|..:|:.|::::..::.. |..|.....:
  Rat   586 QEALLCLEHRYAAFPLPSMSSFNGSHTLLENAADIGGVAIAFQAYRKRITERTG-ELTLPNQELS 649

  Fly   601 NKQLFFVKFAQTWCNGKDNGDKLRRLKTDVHAYDEFRVQGTLSNMPEFSEAFNCKLGTEMNPLKK 665
            ..||||..:||..|.     :.:.:...|.|:....||.|.|||.|:|::.|.|..|:.:||..:
  Rat   650 PYQLFFRSYAQVMCR-----ELISQDPQDTHSPPRLRVHGPLSNSPDFAKHFLCPSGSLLNPSTR 709

  Fly   666 CVVW 669
            |.:|
  Rat   710 CKLW 713

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl7	NP_001285879.1	PepO	43..669	CDD:226118	170/709 (24%)
		M13	52..666	CDD:189000	166/697 (24%)
Kel	NP_001178540.1	PepO	75..713	CDD:226118	169/703 (24%)
		M13	78..711	CDD:189000	166/698 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166344482
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.810