Protein Alignment Nepl7 and Phex

DIOPT Version :10

• Sequence 1: NP_609577.2
• Gene: Nepl7 / 34671
• FlyBaseID: FBgn0032442
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_037136.2
• Gene: Phex / 25512
• RGDID: 3323
• Length: 749
• Species: Rattus norvegicus
• Alignment Length: 751
• Identity: 173/751 - (23%)
• Similarity: 297/751 - (39%)
• Gaps: 192/751 - (25%)

  Fly    44 LLSTMNRTIDPCENFYEFSCGGWKKADLVPEQARNTSFLNAIQHKIDEQIQGFLQNATKRELEDL 108
            ::|.:|.::||||||:.|:|.||...:.:||...:......::|.:|.:::..|:.:..|..:
  Rat    66 IMSKVNLSVDPCENFFRFACDGWISNNPIPEDMPSYGVYPWLRHNVDLKLKALLEKSVSRRRD-- 128

  Fly   109 GVNGTTSAEIKAKQFYASCVEMKANLSLGYQYFMEHDGDRLKERNATYDWMYINFMSKYDIYPLL 173
                 |.|..|||..|:||:..||                               :.|.|..|||
  Rat   129 -----TEAVQKAKILYSSCMNEKA-------------------------------IEKADAKPLL 157

  Fly   174 ALKVHYS---------------TSSRKFDILLTL-----------------------PSKVLAGF 200
            .:..|..               .|.|||.:|.||                       .::.:...
  Rat   158 HILRHSPFRWPVLEANIGPEGVWSERKFSLLQTLATFRGQYSNSVFIRLYVSPDDKASNEHILKL 222

  Fly   201 SEEQLKNMTREFGLDSSAEKVKQFVENFNNLTQFERNLVSLAKSRNETE-------QLNFKEFLV 258
            .:..|....||..||::.| .|.:.:...........|:....||.|.:       ::...|.::
  Rat   223 DQATLSLAVREDFLDNTTE-AKSYRDALYKFMVDTAVLLGANSSRAEHDMKSVLRLEIKIAEIMI 286

  Fly   259 KHK-------HDRLN------------WTRFFELAFNGSQESHWPVLNQLDNI--------NDLV 296
            .|:       ::::|            |..:.:...:.....|...:...:|:        .||.
  Rat   287 PHENRTSEAMYNKMNISELSAMIPQFDWLGYIKKVIDTRLYPHLKDIGPSENVVVRVPQYFKDLF 351

  Fly   297 FFLEQTNLETLKGYIKMRELV--------KFYGLWKTQTKTGGVQSECRSLSE----TYFNYALL 349
            ..|.....:|:..|:..|.:.        :|...|...::.  :|.....|.:    ..|..:.|
  Rat   352 RILGAERKKTIANYLVWRMVYSRIPNLSRRFQYRWLEFSRV--IQGTTTLLPQWDKCVNFIESAL 414

  Fly   350 PWFIGKV-----FDKERRADILSVAKDIKDTFYDLLD-HHTWLDEDTRSQAKTKLASMDILVGYT 408
            |:.:||:     |.::::..:..:.:.::..|.|:|: .:.|:|..|:.:|:.|..::...|||.
  Rat   415 PYVVGKMFVNVHFQEDKKEMMEELIEGVRWAFIDMLEKENEWMDAGTKRKAQEKARAVLAKVGYP 479

  Fly   409 D----DLQHREVIDGV-YSDINMTGN------------------------WFENLCILEGSRARI 444
            :    |....|.:..: :|:.:..||                        ||.|
  Rat   480 EFIMNDTYVNEDLKAIKFSESDYFGNVLQTRKYLAQSDFFWLRKAVPKTEWFTN----------- 533

  Fly   445 RLRSVDKALIPLLMPTRTVNAYYADFLNLAFITIGMAQWPFY-HIDFPDVLKYAGVGNIIGHEMA 508
                          || ||||:|:...|......|..|.||: ..::|..|.|..:|.|:|||..
  Rat   534 --------------PT-TVNAFYSASTNQIRFPAGELQKPFFWGTEYPRSLSYGAIGVIVGHEFT 583

  Fly   509 HGFDSYCYQYNYDGKKTNWWSSASLRNFKERYRCLESQYNKFI--LMGVQTNGSLTSGDNIADNV 571
            ||||:...:|:.:|....|||..|...|||:.:|:.:||:.:.  ..|:...|..|.|:|||||.
  Rat   584 HGFDNNGRKYDKNGNLDPWWSVDSEEKFKEKTKCMINQYSNYYWKKAGLNVKGKRTLGENIADNG 648

  Fly   572 GTRMAYYAFKRKTGD-KAWLEKP-LRGVNFNNKQLFFVKFAQTWCNGKDNGDKLRRLKTDVHAYD 634
            |.|.|:.|:::...| :..:|:| |.|:.|.|.||||:.:|...||.........:::...|:..
  Rat   649 GLREAFRAYRKWINDRRQGVEEPLLPGITFTNNQLFFLSYAHVRCNSYRPEAAREQVQIGAHSPP 713

  Fly   635 EFRVQGTLSNMPEFSEAFNCKLGTEMN-PLKKCVVW 669
            :|||.|.:||..||.:||||...:.|| ....|.:|
  Rat   714 QFRVNGAISNFEEFQKAFNCPANSTMNRGADSCRLW 749

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl7	NP_609577.2	M13	52..666	CDD:341056	169/738 (23%)
Phex	NP_037136.2	M13	74..740	CDD:341056	167/732 (23%)