Protein Alignment Nepl7 and nep-8

DIOPT Version :10

• Sequence 1: NP_609577.2
• Gene: Nepl7 / 34671
• FlyBaseID: FBgn0032442
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_001309548.1
• Gene: nep-8 / 184631
• WormBaseID: WBGene00017553
• Length: 686
• Species: Caenorhabditis elegans
• Alignment Length: 643
• Identity: 130/643 - (20%)
• Similarity: 256/643 - (39%)
• Gaps: 83/643 - (12%)

  Fly    44 LLSTMNRTIDPCENFYEFSCGGWKKADLVPEQARNTSFLNAIQHKIDEQIQGFLQNATKRELEDL 108
            ||:..:.::|||.:|::.|||.:.      ||:.:.|.|...:|.:.:||:.||....
 Worm    68 LLNYQDPSVDPCVDFFQHSCGRFH------EQSVSESRLQKKKHILRKQIREFLHKIQ------- 119

  Fly   109 GVNGTTSAEIKAKQFYASCVEMKANLSLGYQYFMEHDGDRLKERNATYD----------WMYINF 163
              |.|:.:|...|..:..|...|...:..|:.          .|:|.:|          |..::.
 Worm   120 --NSTSKSENLMKLVFDKCEASKKTSNDNYKI----------SRDAIHDVFNDIKKIGAWPLLDK 172

  Fly   164 M---SKYDIYPLLA--------------LKVHYSTSSRKFDILLTLPSKVLAGFSEEQLKNMTRE 211
            .   ||:|:..:|:              |.....|..:...|..||.|.|........:..:...
 Worm   173 NWDGSKFDLNEMLSNLVKLGATNLGLFQLDFRILTEGKFVRIAPTLGSIVHNSTMISMISEILEA 237

  Fly   212 FGLDSSAEKVKQFVENFNNLTQFERNLVSLAKSRNE---------TEQLNFKEFLVKHKHDRLNW 267
            .|:...:|::.:..|.:::|.      :.|||.::.         ...:||...:.:..|.....
 Worm   238 NGVQPDSEEISKEFEEYSSLQ------MKLAKYQSSGKLSISLPGVRSINFSSLITEMIHPSRVS 296

  Fly   268 TRFFELAFNGSQESHWPVLNQLDNINDLVFFLEQTNLETLKGYIKMRELVKFYGLWKTQTKTGGV 332
            ..|.::....|:...:...|:.::::.::   |.|:.:||..::....:...|.:.|     |..
 Worm   297 KIFGKIRVVTSEHPLFFKSNETESLDTII---ESTSNKTLANFLIFNYIQSSYNIMK-----GAR 353

  Fly   333 QSECRSLSETYFNYALLPWFIGKVFDKERRADILSVAKDIKDTFYDLLDHHTWLDEDTRSQAKTK 397
            :..|.......|..|.|..|:....||..|..:..:.:::|....:::.....|....:.....|
 Worm   354 RGNCEDDVRREFPRASLRVFMRNFVDKGNRDGVKKLTEELKKNTLEMIQDTENLAPPVKESMLKK 418

  Fly   398 LASMDILVGYTDDLQHREVIDGVYS--DINMTGNWFENLCILEGSRARIRLRSV-DKALIPLLMP 459
            :.::.:.:||.|.......:|..:.  |::.|.:::.....|...|:..::..: .:..|..:..
 Worm   419 VEAIKVTIGYPDHFDPPGTLDKEFENFDLDSTDSYYRIFQKLNRLRSEQQMEFIAGETPISPIKE 483

  Fly   460 TRTVNAYYADFLNLAFITIGMAQWPFYHIDFPDVLKYAGVGNIIGHEMAHGFDSYCYQYNYDGKK 524
            ...|||.|....|...:.......||:.|.:||.:.....|.:|.||:.|..|:....|:.:||.
 Worm   484 VLKVNANYKRSKNALTVFAPFLDDPFFDITYPDYVNLFFSGFLIAHEIGHSVDANGLGYDENGKP 548

  Fly   525 TNWWSSASLRNFKERYRCLESQYNKF--ILMGVQTNGSLTSGDNIADNVGTRMAYYAFKRKTGDK 587
            .:......:..:.::.:||..||:.:  .:.|.:.||:.:..:.|||.||..:.:.|:|:....|
 Worm   549 MDGIRLEHVTEYGKQGQCLVDQYDNYDDPVYGKKMNGTHSINEIIADWVGHEVTWRAYKKMDTSK 613

  Fly   588 AWLEKPLRGVNFNNKQLFFVKFAQTWCNGKDNGDKLRRLKTDVHAYDEFRVQGTLSNM 645
            ......|:.:|.:  ||:|...:..:|..:|.......|| ||:..|.|||.|..:.:
 Worm   614 MLSLIGLKDINMD--QLYFRVQSLLFCRERDTISLEETLK-DVYPTDNFRVNGAYARV 668

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl7	NP_609577.2	M13	52..666	CDD:341056	128/635 (20%)
nep-8	NP_001309548.1	M13	76..664	CDD:341056	127/629 (20%)