Protein Alignment Nepl7 and nep-22

DIOPT Version :10

• Sequence 1: NP_609577.2
• Gene: Nepl7 / 34671
• FlyBaseID: FBgn0032442
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_509528.1
• Gene: nep-22 / 181144
• WormBaseID: WBGene00020788
• Length: 798
• Species: Caenorhabditis elegans
• Alignment Length: 827
• Identity: 181/827 - (21%)
• Similarity: 319/827 - (38%)
• Gaps: 212/827 - (25%)

  Fly     4 ALWATLISLTLIGRVLA-------NDLFSLPPA--------TNHREEMLEDYGRFLLSTMNRTID 53
            |:.:.::::.::|.|..       |.::...||        |.:..........:||:.::.|:|
 Worm    20 AIGSLVLNIIILGNVNTLTTTVNNNPVYHYTPAPQVNSTPGTVNTSPSYTQAANYLLNGLDDTVD 84

  Fly    54 PCENFYEFSCGGW-KKADLVPEQARNTSFLNAIQHKIDEQIQGFLQNATKRELEDLGVNGTTSAE 117
            ||::||.|:|..: :..||   |....|.|...     :|.|..:.:.....|..:.|..||:::
 Worm    85 PCQDFYAFTCNKFLQNTDL---QKLGRSRLGTY-----DQAQVDVYSEIVAALSKIDVTSTTTSK 141

  Fly   118 IK--AKQFYASCVEMKANLSL-----------------GYQYFMEHDGDRLKERNATYDWM---- 159
            .:  .|..:.:|   |.||:.                 |..:|    |:.|| .|..| ||
 Worm   142 TERITKAAFETC---KNNLASPADKTAVVYAEITSLFGGVPFF----GEPLK-TNVDY-WMVAGQ 197

  Fly   160 -----------YINFMSKYD------IY---PLLAL------KVHY--STSSRKFDILLTLPSKV 196
                       |....|.|.      :|   |.|:|      |..|  ..:.|..|:     :.:
 Worm   198 IEQKHAVGTLTYTIASSDYKDHTKNALYTGPPGLSLARDFYVKPQYIAEVNQRVSDV-----NDL 257

  Fly   197 LAGFSEEQLKNMTREFGLDSSAEKVKQF-------------VENFNNLTQFERNLVSLAKSRNET 248
            |..|:....||:..: .|.::|::|..|             :.|:    |.:.|..::|.:....
 Worm   258 LTAFANAAKKNVGAD-ALLAAAQEVVNFEVQIAMASWPDDLLRNY----QQQYNPYNIASATTAY 317

  Fly   249 EQLNFKEFLVKHKH------DRLNWT---------RFFELAFNGSQESHWPVLNQL--------- 289
            ..:|:|.:|.:..|      |:.|:.         .:....|:|...:...|.|.:
 Worm   318 RAINWKSYLGQLFHGVASDADQANYNIVVTEPSYFAWLNSVFDGKTSNSTVVANYMIAQLLADES 382

  Fly   290 DNINDLVFFL-EQTN-----LETLKGYIKM--RELVKFYGLWKTQTKTGGVQSECRSLSETYFNY 346
            |.||.....: ..||     |...:|..|:  ||.        ......|:...|..|...|
 Worm   383 DFINPATAKVSSDTNYIHYALRNGRGIKKIGKREY--------RMADLDGISEGCMDLLTAY--- 436

  Fly   347 ALLPWFIGKVFDKERRADILSVAKDIKD-------TFYDLLDHHTWLDEDTRSQAKTKLASM--- 401
              :|:..|.|:.|. :::...|..|:||       .|..::|...|:|..::::|..|..|:
 Worm   437 --MPYGTGYVYVKS-KSERNKVQADVKDQTTLIINNFQGMIDSLNWMDTFSKNRAHNKSDSLVKN 498

  Fly   402 ----DILVGYTDDL--------QHREVIDGVYSDINMTGNWFENLCILEGSRAR--IRLRSVDKA 452
                :.:.|..:|.        .:..:||....|.|.....|  ..:.:|...|  .|:......
 Worm   499 FGWPEAMFGDFNDFTTVDAYNQDYASIIDLYTKDKNDIYGIF--AVLKKGMEVREFFRIMGEPAD 561

  Fly   453 LIPLLMPTRTVNAYYADFLNLAFITIGMAQW--PFYHIDFPDVLKYAGVGNIIGHEMAHGFDSYC 515
            ....|.....|||:|....|  .||...|.|  |:|::::|....:||.|...|||:.||:|...
 Worm   562 RTNFLQSPAMVNAWYQPERN--SITFPYAAWNPPYYNLNYPQAYNFAGQGGTGGHELTHGYDDEG 624

  Fly   516 YQYNYDGK-------KTNWWSSASLRNFKERYRCLESQYNKFILMGVQ-----------TNGSLT 562
            .|:.::|:       |..|..:.|...|.:..:|:.:|::      .|           .||:.|
 Worm   625 VQFGFNGELTDCSWNKCGWMDTNSSSGFIDMAQCVVTQFS------TQCCPEKTGNIHCANGATT 683

  Fly   563 SGDNIADNVGTRMAYYAFKR--KTGDKAWLEKPLRGV-NFNNKQLFFVKFAQTWCNGKDNGDKLR 624
            .|:||||..|.:.||.::::  .|..|...|..|.|: |:...|:|::.:..:||..:.:.:.:.
 Worm   684 QGENIADLGGQQAAYRSYRQYVATTRKGVEEDRLPGLENYTPNQIFWITYGYSWCMKQSDANLVH 748

  Fly   625 RLKTDVHAYDEFRVQGTLSNMPEFSEAFNCKLGTEM--NPLKKCVVW 669
            :|.|:.|:..:.|....:.::|||.:.|.|..|:.|  .|..:|.||
 Worm   749 QLLTNPHSPAQCRTNQVMQDIPEFGKDFGCVRGSPMYPEPSGRCKVW 795

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl7	NP_609577.2	M13	52..666	CDD:341056	168/759 (22%)
nep-22	NP_509528.1	M13	83..793	CDD:341056	168/760 (22%)