Protein Alignment Nepl7 and nep-16

DIOPT Version :9

• Sequence 1: NP_001285879.1
• Gene: Nepl7 / 34671
• FlyBaseID: FBgn0032442
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_001023203.2
• Gene: nep-16 / 177541
• WormBaseID: WBGene00018472
• Length: 868
• Species: Caenorhabditis elegans
• Alignment Length: 723
• Identity: 132/723 - (18%)
• Similarity: 254/723 - (35%)
• Gaps: 199/723 - (27%)

  Fly    44 LLSTMNRTIDPCENFYEFSCGGW--KKADLVPEQARNTSFLNAIQHKIDEQIQGFLQNATKRELE 106
            |.|.::..|:||||||.:||..:  :.||      :..|||:.::.:...::...|.:.....|.
 Worm   246 LSSCIDDEIEPCENFYRYSCQRYHSQTAD------KQMSFLSQLKDESLRRMHSLLSSEEDSRLL 304

  Fly   107 DLGVNGTTSAEIKAKQFYASC---VEMKANLSLGYQYFME--------------HDGDRLKERNA 154
                  ..||.: ::..|::|   |...:|.......|:.              |......||:|
 Worm   305 ------PKSARL-SRSLYSACMNAVLRSSNAPTDLLTFIRNFPCGPLLRDCQNFHADSYSWERHA 362

  Fly   155 -TYDWMYINFMSKY-------DIYP------LLALKVHYST----------------SSRKFDIL 189
             ..||    :..:|       |::|      :|.:|....|                |..:|:.|
 Worm   363 GMLDW----YAGRYNLIVYDRDVHPQDRSKIILQIKPPDLTPIVGLIERDLIDLARPSPTEFEPL 423

  Fly   190 --LTLPSKVLAGFSEEQLKNMTREFGLDSSAEKVKQFVENFNNLTQFERNL------VSLAKSRN 246
              |:|...:|:.|:.:.|....|:  :.|..::|.:.:.:.....:...:|      :::.:...
 Worm   424 LQLSLRQNLLSAFARDSLLRDPRD--VQSQLDEVARLMVDLYISARQSASLTPNTTYMTIGEMFQ 486

  Fly   247 ETEQLNFKEFLVKHKHDRLNWTRFFELAFNGSQESHWPVLNQLDNINDLVFFLEQTNLETLKGY- 310
            ...||..:|||.....:...||           |:....:...|....|...:.||:.:.:..|
 Worm   487 ALPQLYLREFLDAQLSNTYRWT-----------ETDMLSIQDYDYFARLSDIMAQTSRQAVANYL 540

  Fly   311 --IKMRELVKF-------YGLWKTQTKTGGVQSECRSLSETYFNYALLPWFIGK--VFDK-ERRA 363
              :.:..|.::       || |:          ||.....::        .||:  ..|| .:..
 Worm   541 LTVTVWNLKQYSYSPRDQYG-WR----------ECVDQISSF--------EIGRKMYVDKASQTI 586

  Fly   364 DILSVAKDIKDTFYDLLDHHTWLDEDTRSQAKTKLASMDILVGYTDDLQHREVIDGVYSDINMTG 428
            |:..:.:.:::...|.|..|    ..|..|..:.:..:...||:...||:.|:|....|.:::..
 Worm   587 DLPKIQEFLQNLKIDFLSVH----RSTPLQYLSNINRLGFYVGFPRRLQNEELIWKPVSQVSLNE 647

  Fly   429 NWFENLCILEGSRAR--------IRLRSVDKALIPLLMPTRTVNAYYADFLNLAFITIGMA---- 481
            ..:.:..|..|...|        ..|.:.|....|:..||...|:      |:..|.|.:|
 Worm   648 TDYFDSMIRVGKAERDYTMSQIGTYLDNDDTTTFPISDPTMLYNS------NVGAIVIPLAFIEP 706

  Fly   482 -------QWPFYHIDFPDVLKYAGVG----NIIGHEMAHGFDSYCYQYNYDGKKTNWWSSASLRN 535
                   :.|.|.|       |:.:|    .:|......|.|           ||:
 Worm   707 PIYLPGDEVPMYGI-------YSSLGITTLQMISKVFWQGLD-----------KTS--------- 744

  Fly   536 FKERYRCLESQYNKFILMGVQTNGS----LTSGDNIADNVGTRMAYYAFKRKTGD-KAWLEKPLR 595
               :..||::.:..|:....|.:.:    |.:...:||  ..:.|.|::.:...| ....||.|.
 Worm   745 ---QLECLDNVFRGFLDANRQRSPNIEPELLATIELAD--AFKSALYSYAKWQNDHHIHHEKTLP 804

  Fly   596 GV-NFNNKQLFFVKFAQTWCNGKDNGDKLRRLKTDVHAYDEFRVQGTLSNMPEFSEAFNCKLGTE 659
            .. :.::.:...:.|:..:|:|:.         ::..:..|..:.....|...||..|||...:.
 Worm   805 AFDSTDSMRSLMLTFSTMFCSGEG---------SEPGSDYEAMINTVAENSRMFSIHFNCNNSSR 860

  Fly   660 MNPLKKCV 667
            :...:.|:
 Worm   861 LYNRRTCL 868

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl7	NP_001285879.1	PepO	43..669	CDD:226118	132/723 (18%)
		M13	52..666	CDD:189000	129/712 (18%)
nep-16	NP_001023203.2	GluZincin	254..>725	CDD:387391	100/536 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010