Protein Alignment Nepl7 and nep-12

DIOPT Version :9

• Sequence 1: NP_001285879.1
• Gene: Nepl7 / 34671
• FlyBaseID: FBgn0032442
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_001364537.1
• Gene: nep-12 / 173824
• WormBaseID: WBGene00017842
• Length: 832
• Species: Caenorhabditis elegans
• Alignment Length: 686
• Identity: 186/686 - (27%)
• Similarity: 324/686 - (47%)
• Gaps: 78/686 - (11%)

  Fly    45 LSTMNRTIDPCENFYEFSCGGWKKADLVPEQARNTSFLNAIQHKIDEQIQGFLQNATKRELEDLG 109
            |:.|||..:|||:||||:||.:....::.|..:..:.|:.::.::|..::..|:. |.||
 Worm   164 LNNMNRDANPCEDFYEFACGKYATRKVIAEHEKKVTVLSEMKKEMDRHLKDILEK-TSRE----- 222

  Fly   110 VNGTTSAEIKAKQFYASCVEMKANLSLGYQYFM---EHDGDRLKERNATYD-----W-MYINFMS 165
             |.|.|.:: |:.::.||::..:...||.|..|   .:.|......||.:|     | :....::
 Worm   223 -NTTRSMKL-AQIYFDSCMDEFSQDDLGVQPLMSMISNLGGWPLLTNARFDSIDFQWEVLAGHLA 285

  Fly   166 KYDIYPLLALKVHYSTSSRKFDILLTLP----------------SKVLAGFSEEQLKNMTREFGL 214
            .|.:..:..:.||.|......::|:..|                |.|...:..:.:.::....|:
 Worm   286 LYGVDGIFRVFVHSSFDDSDKNVLMFSPPKLFLEKKKFYREVPSSNVYLQYYRQYILSLLSLLGV 350

  Fly   215 DSSAEK-VKQFVENFNNLTQFERNLVSLAK---SRNET---EQLNFKEFLVKHKHDRLNWTRFFE 272
            |...|. |.::  ..:::..|||.:.:|.:   |||.:   ..:.|.||  |.|:|::||..||.
 Worm   351 DMEDETGVIEY--QVDDIIDFERRIANLTRIELSRNHSSINNMITFGEF--KRKYDKINWDAFFN 411

  Fly   273 LAFNGSQESHWP---VLNQLD--NINDLVFFLEQTNLETLKGYIKMRELVKFYGLW--------- 323
            ....|:. ...|   |:|.:|  ..::|...::...|.::..:: |..||..|.::
 Worm   412 EEMRGNL-GRMPDSLVINVVDVNYFDNLYSLIKSKPLSSINNFL-MWCLVSNYDMYLPAKYRKPM 474

  Fly   324 -KTQTKTGGVQSE------CRSLSETYFNYA--LLPWFIGKVFDKERRADILSVAKDIKDTFYDL 379
             ..:.|..||.|:      |  :.|...|.|  |...:..|.|.|:.:.....:.:|:|......
 Worm   475 LDFRQKMYGVSSDDPLWEVC--VGEVRENLAMPLSTEYAQKFFTKKDKLVAEDMIRDLKKAMEQT 537

  Fly   380 LDHHTWLDEDTRSQAKTKLASMDILVGYTDDLQHREVIDGVYSDINMTGN-WFENLCILEGSRAR 443
            |.:..|:||.||..|..||.:|...:|:.|.|.:...:...|:.:.:|.| :|:|...|:.:..|
 Worm   538 LLNADWIDESTREAALMKLDAMGHKIGFPDSLLNETAVLLPYAGVRLTANQYFDNAISLKKAAYR 602

  Fly   444 IRLRSVDK--ALIPLLMPTRTVNAYYADFLNLAFITIGMAQWPFYHIDFPDVLKYAGVGNIIGHE 506
            ..|..:.:  :||....|...|:|::....|......|:.|:|.:..|.|....|..:|..||||
 Worm   603 DALSKLHRTPSLIDWASPIIAVDAFHYFTGNEIIFPAGILQFPMFVPDAPAFSNYGAIGMGIGHE 667

  Fly   507 MAHGFDSYCYQYNYDGKKTNWWSSASLRNFKERYRCLESQYNKFI--LMGVQTNGSLTSGDNIAD 569
            :.||:|....||:..|....||.:.::..|:::.:|..:||...|  ..|.:.:|.:|.|:||||
 Worm   668 ITHGYDDLGAQYDDKGNLRGWWHTETMTTFQKKKQCFVAQYGSKIEPQTGRKVDGKMTIGENIAD 732

  Fly   570 NVGTRMAYYAFKRKTGDKAWLEKPLRGV-NFNNKQLFFVKFAQTWCNGKDNGDKLRRLKTDVHAY 633
            |.|.|:|:.|::.:: |:....:.|.|: :|:..||||:.:|.|||...........:.||||:.
 Worm   733 NGGLRVAFQAYQLRS-DREKETRRLPGLTDFSPNQLFFLAYANTWCEALKPSAIDHIMDTDVHSL 796

  Fly   634 DEFRVQGTLSNMPEFSEAFNCKLGTEMNPLKKCVVW 669
            ..|||...|.|:|.||:.|:|.:|:.|||.:||.:|
 Worm   797 GMFRVNVPLQNLPAFSKEFDCPIGSPMNPFEKCRIW 832

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl7	NP_001285879.1	PepO	43..669	CDD:226118	185/684 (27%)
		M13	52..666	CDD:189000	179/674 (27%)
nep-12	NP_001364537.1	M13	171..830	CDD:341056	180/675 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	6	5.880