Protein Alignment Nepl7 and Mme

DIOPT Version :10

• Sequence 1: NP_609577.2
• Gene: Nepl7 / 34671
• FlyBaseID: FBgn0032442
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_032630.2
• Gene: Mme / 17380
• MGIID: 97004
• Length: 750
• Species: Mus musculus
• Alignment Length: 763
• Identity: 200/763 - (26%)
• Similarity: 329/763 - (43%)
• Gaps: 140/763 - (18%)

  Fly     2 VNALWATLISLTLIGRVLANDLFSLPPATNHREEMLEDYGRFLLSTMNRTIDPCENFYEFSCGGW 66
            |..|..|:|::|:|......|     .......:.::...| |:..|:.:::||.:|::::||||
Mouse    33 VLVLLLTIIAVTMIALYATYD-----DGICKSSDCIKSAAR-LIQNMDASVEPCTDFFKYACGGW 91

  Fly    67 KKADLVPEQARNTSFLNAIQHKIDEQIQGFLQNATKRELEDLGVNGTTSAEIKAKQFYASCVEMK 131
            .|.:::||.:...|..:.::.:::..::..||   :.:.||:      .|..|||..|.||:...
Mouse    92 LKRNVIPETSSRYSNFDILRDELEVILKDVLQ---EPKTEDI------VAVQKAKTLYRSCINES 147

  Fly   132 ANLSLGYQYFME------------HDGDRLKERNATYDWMYINFMSKYDIYPLLALKVHYSTSSR 184
            |..|.|.|..::            .:.|:....:.|.:.......|||....|:...|.....:.
Mouse   148 AIDSRGGQPLLKLLPDIYGWPVASDNWDQTYGTSWTAEKSIAQLNSKYGKKVLINFFVGTDDKNS 212

  Fly   185 KFDIL------LTLPSK---VLAGFSEE-------------QLKNMTREFGLDSSAEKVKQFVEN 227
            ...|:      |.|||:   ...|..:|             :|....:...:|.:     |....
Mouse   213 TQHIIHFDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEQSLPIDEN-----QLSLE 272

  Fly   228 FNNLTQFER---NLVSLAKSRNETEQLNFKEFLVKHKHDRLNWTRFFELAFNGSQESHW------ 283
            .|.:.:.|:   |..:..:.||:...|..|..|.|.:::       |.|..||...| |
Mouse   273 MNKVMELEKEIANATTKPEDRNDPMLLYNKMTLAKLQNN-------FSLEVNGKSFS-WSNFTNE 329

  Fly   284 ---------------------------PVLNQ-----LDN------INDLVFFLEQTNLETLKGY 310
                                       |:|.:     |.|      |.|||..|.:...|:...:
Mouse   330 IMSTVNINIQNEEEVVVYAPEYLTKLKPILTKYSPRDLQNLMSWRFIMDLVSSLSRNYKESRNAF 394

  Fly   311 IKMRELVKFYGLWKTQTKTGGVQSECRSLSETYFNYALLPWFIGKVFDKERRADILSVAKDIKDT 375
            .|        .|:.|.::| .....|.:........|:...::...|..|.:..:..:...|::.
Mouse   395 RK--------ALYGTTSET-ATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREV 450

  Fly   376 FYDLLDHHTWLDEDTRSQAKTKLASMDILVGYTDD-LQHREVIDGVYSDIN-MTGNWFENLCILE 438
            |...||..||:|.:|:.:|:.|..::...:||.|| :.:...::..|.::| ....:|||  |::
Mouse   451 FIQTLDDLTWMDAETKKKAEEKALAIKERIGYPDDIISNENKLNNEYLELNYREDEYFEN--IIQ 513

  Fly   439 G-----SRARIRLR-SVDKALIPLLMPTRTVNAYYADFLNLAFITIGMAQWPFYHIDFPDVLKYA 497
            .     |:...:|| .|||.  ..:.....|||:|:...|......|:.|.||:.....:.|.|.
Mouse   514 NLKFSQSKQLKKLREKVDKD--EWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYG 576

  Fly   498 GVGNIIGHEMAHGFDSYCYQYNYDGKKTNWWSSASLRNFKERYRCLESQYNKF---ILMGVQTNG 559
            |:|.:||||:.||||.....:|.||...:||:..|..|||::.:|:..||..|   :..|...||
Mouse   577 GIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSANNFKDQSQCMVYQYGNFSWDLAGGQHLNG 641

  Fly   560 SLTSGDNIADNVGTRMAYYAFK---RKTGDKAWLEKPLRGVNFNNKQLFFVKFAQTWCNGKDNGD 621
            ..|.|:|||||.|...||.|::   :|.|:    ||.|.|::.|:|||||:.|||.||.......
Mouse   642 INTLGENIADNGGIGQAYRAYQNYVKKNGE----EKLLPGLDLNHKQLFFLNFAQVWCGTYRPEY 702

  Fly   622 KLRRLKTDVHAYDEFRVQGTLSNMPEFSEAFNCKLGTEMNPLKKCVVW 669
            .:..:|||||:...||:.|||.|..||::||:|:..:.|||.:||.||
Mouse   703 AVNSIKTDVHSPGNFRIIGTLQNSAEFADAFHCRKNSYMNPERKCRVW 750

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl7	NP_609577.2	M13	52..666	CDD:341056	186/708 (26%)
Mme	NP_032630.2	Stop-transfer sequence. /evidence=ECO:0000255	16..23
		M13	77..748	CDD:341056	187/709 (26%)