Protein Alignment Nepl7 and nep-3

DIOPT Version :9

• Sequence 1: NP_001285879.1
• Gene: Nepl7 / 34671
• FlyBaseID: FBgn0032442
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_494679.2
• Gene: nep-3 / 173730
• WormBaseID: WBGene00016778
• Length: 634
• Species: Caenorhabditis elegans
• Alignment Length: 661
• Identity: 162/661 - (24%)
• Similarity: 263/661 - (39%)
• Gaps: 141/661 - (21%)

  Fly    44 LLSTMNRTIDPCENFYEFSCGGWKKADLVPEQARNTSFLNAIQHKIDEQIQGFLQNATKRELEDL 108
            ||:..:.::|||||||:.:||.:.:.::                 ||.......|...||.:.|.
 Worm    74 LLNFQDPSVDPCENFYQAACGKYNEHNV-----------------IDGSRTAQKQQIVKRLIRDF 121

  Fly   109 ---GVNGTTSAEIKAKQFYASCVEMKANLSLGYQYFMEHDGDRLKERNATYDWMYINFMSKYDIY 170
               ..:.|:.:|...|..|..|.|.|....||.|..::.              :::| :.|...:
 Worm   122 LHKNQSSTSKSENSMKLLYEKCKEAKTIKVLGNQNLLQE--------------IFMN-IQKIGSW 171

  Fly   171 PLLALKVHYSTSSRKFDILLTLPSKVLAGFSEEQLKNMTREFGLDSSAEKVKQFVE-----NF-- 228
            |:|    ..:...:||::...|.|.:..|.|         .||..........|||     ||
 Worm   172 PVL----DENWDGKKFNLNEMLLSLIRLGVS---------NFGFFEIIISSDAFVEIKPARNFPT 223

  Fly   229 -NNLTQ----------FERNLVSLAKSRNETEQLNFKEFLVKHKHDRLNWTRFFELAFNGSQESH 282
             .||:.          |:.|:.::.....|.|.|         :.:..:..|..:...|.|.
 Worm   224 RENLSDIISKVFLGNGFQPNITAIENDLREYENL---------QRELKSLERLIQTTPNRSL--- 276

  Fly   283 WPVLNQLDNINDLVF-FLEQTNLETLKGYIKMRELVKFYGLWKTQTKTGGVQSECRSLSETYFNY 346
                     :|.|:| :|:...||    |.::.|                  .:|..:...:...
 Worm   277 ---------VNYLIFNYLKSVMLE----YKRLPE------------------EQCEGVVIDFLPR 310

  Fly   347 ALLPWFIGKVFDKERRADILSVAKDIKDTFYDLLDHHTWLDEDTRSQAKTKLASMDILVGYTDDL 411
            |....|:....|||.|..:..:.:|:|..|.|::...|||:|:::..|..|:.::..::||.|..
 Worm   311 ASTRVFVQNFLDKENRKYVAGMIEDVKMGFIDMIQESTWLNEESKKVAVQKVKNIKSMIGYPDFF 375

  Fly   412 QHREVIDGVYSDINMTGNWFENLCILEGSRARIRLRSVDK-----------ALIPL--LMPTRTV 463
            :....:|..:.|:|          |.:.......:|.:.|           :.|||  ..|....
 Worm   376 EPPGTLDRSFKDLN----------IEQTDSYHTIVRKIQKFTNEQCMEFVASEIPLDPRQPILHA 430

  Fly   464 NAYYADFLNLAFITIGMAQWPFYHIDFPDVLKYAGVGNIIGHEMAHGFDSYCYQYNYDGKKTNWW 528
            ||:|.: .|...|...:...|.:...||..:..|.:||::.||:.|.||.....|:..|::..|.
 Worm   431 NAFYQN-TNFLAILAPVLDDPIFDTTFPRYVNLAVIGNVLAHEIGHAFDHTGINYDDAGQQRIWL 494

  Fly   529 SSASLRNFKERYRCLESQYNKF--ILMGVQTNGSLTSGDNIADNVGTRMAYYAFKRKTGDKAWLE 591
            :......:.:|.|||..|::::  ...|...|||.|..:..||..|...|:..||:.....   |
 Worm   495 TPEDSEEYGKRLRCLLRQHDEYDDPDFGRNLNGSKTLHEISADRFGVEAAWRTFKKLDLSN---E 556

  Fly   592 KPLRGV-NFNNKQLFFVKFAQTWCNGKDNGDKLRRLKTDVHAYDEFRVQGTLSNMPEFSEAFNCK 655
            ..:.|. |||..||:|...|..||..:|..|....|:.: |..:.|||.|..:|||:|:|.|||.
 Worm   557 SEIVGFQNFNIDQLYFRTAALIWCRQRDTTDLQYALQRE-HPTNNFRVNGIYANMPQFAETFNCP 620

  Fly   656 LGTEMNPLKKC 666
            ||:.|||.|||
 Worm   621 LGSPMNPKKKC 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl7	NP_001285879.1	PepO	43..669	CDD:226118	162/661 (25%)
		M13	52..666	CDD:189000	158/651 (24%)
nep-3	NP_494679.2	M13	82..631	CDD:189000	158/651 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920