Protein Alignment Nepl7 and nep-3

DIOPT Version :10

• Sequence 1: NP_609577.2
• Gene: Nepl7 / 34671
• FlyBaseID: FBgn0032442
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_494679.2
• Gene: nep-3 / 173730
• WormBaseID: WBGene00016778
• Length: 634
• Species: Caenorhabditis elegans
• Alignment Length: 661
• Identity: 162/661 - (24%)
• Similarity: 263/661 - (39%)
• Gaps: 141/661 - (21%)

  Fly    44 LLSTMNRTIDPCENFYEFSCGGWKKADLVPEQARNTSFLNAIQHKIDEQIQGFLQNATKRELEDL 108
            ||:..:.::|||||||:.:||.:.:.::                 ||.......|...||.:.|.
 Worm    74 LLNFQDPSVDPCENFYQAACGKYNEHNV-----------------IDGSRTAQKQQIVKRLIRDF 121

  Fly   109 ---GVNGTTSAEIKAKQFYASCVEMKANLSLGYQYFMEHDGDRLKERNATYDWMYINFMSKYDIY 170
               ..:.|:.:|...|..|..|.|.|....||.|..::.              :::| :.|...:
 Worm   122 LHKNQSSTSKSENSMKLLYEKCKEAKTIKVLGNQNLLQE--------------IFMN-IQKIGSW 171

  Fly   171 PLLALKVHYSTSSRKFDILLTLPSKVLAGFSEEQLKNMTREFGLDSSAEKVKQFVE-----NF-- 228
            |:|    ..:...:||::...|.|.:..|.|         .||..........|||     ||
 Worm   172 PVL----DENWDGKKFNLNEMLLSLIRLGVS---------NFGFFEIIISSDAFVEIKPARNFPT 223

  Fly   229 -NNLTQ----------FERNLVSLAKSRNETEQLNFKEFLVKHKHDRLNWTRFFELAFNGSQESH 282
             .||:.          |:.|:.::.....|.|.|         :.:..:..|..:...|.|.
 Worm   224 RENLSDIISKVFLGNGFQPNITAIENDLREYENL---------QRELKSLERLIQTTPNRSL--- 276

  Fly   283 WPVLNQLDNINDLVF-FLEQTNLETLKGYIKMRELVKFYGLWKTQTKTGGVQSECRSLSETYFNY 346
                     :|.|:| :|:...||    |.::.|                  .:|..:...:...
 Worm   277 ---------VNYLIFNYLKSVMLE----YKRLPE------------------EQCEGVVIDFLPR 310

  Fly   347 ALLPWFIGKVFDKERRADILSVAKDIKDTFYDLLDHHTWLDEDTRSQAKTKLASMDILVGYTDDL 411
            |....|:....|||.|..:..:.:|:|..|.|::...|||:|:::..|..|:.::..::||.|..
 Worm   311 ASTRVFVQNFLDKENRKYVAGMIEDVKMGFIDMIQESTWLNEESKKVAVQKVKNIKSMIGYPDFF 375

  Fly   412 QHREVIDGVYSDINMTGNWFENLCILEGSRARIRLRSVDK-----------ALIPL--LMPTRTV 463
            :....:|..:.|:|          |.:.......:|.:.|           :.|||  ..|....
 Worm   376 EPPGTLDRSFKDLN----------IEQTDSYHTIVRKIQKFTNEQCMEFVASEIPLDPRQPILHA 430

  Fly   464 NAYYADFLNLAFITIGMAQWPFYHIDFPDVLKYAGVGNIIGHEMAHGFDSYCYQYNYDGKKTNWW 528
            ||:|.: .|...|...:...|.:...||..:..|.:||::.||:.|.||.....|:..|::..|.
 Worm   431 NAFYQN-TNFLAILAPVLDDPIFDTTFPRYVNLAVIGNVLAHEIGHAFDHTGINYDDAGQQRIWL 494

  Fly   529 SSASLRNFKERYRCLESQYNKF--ILMGVQTNGSLTSGDNIADNVGTRMAYYAFKRKTGDKAWLE 591
            :......:.:|.|||..|::::  ...|...|||.|..:..||..|...|:..||:.....   |
 Worm   495 TPEDSEEYGKRLRCLLRQHDEYDDPDFGRNLNGSKTLHEISADRFGVEAAWRTFKKLDLSN---E 556

  Fly   592 KPLRGV-NFNNKQLFFVKFAQTWCNGKDNGDKLRRLKTDVHAYDEFRVQGTLSNMPEFSEAFNCK 655
            ..:.|. |||..||:|...|..||..:|..|....|:.: |..:.|||.|..:|||:|:|.|||.
 Worm   557 SEIVGFQNFNIDQLYFRTAALIWCRQRDTTDLQYALQRE-HPTNNFRVNGIYANMPQFAETFNCP 620

  Fly   656 LGTEMNPLKKC 666
            ||:.|||.|||
 Worm   621 LGSPMNPKKKC 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl7	NP_609577.2	M13	52..666	CDD:341056	158/651 (24%)
nep-3	NP_494679.2	M13	82..631	CDD:341056	158/651 (24%)