Protein Alignment Nepl7 and nep-10

DIOPT Version :9

• Sequence 1: NP_001285879.1
• Gene: Nepl7 / 34671
• FlyBaseID: FBgn0032442
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_494532.2
• Gene: nep-10 / 173684
• WormBaseID: WBGene00017555
• Length: 711
• Species: Caenorhabditis elegans
• Alignment Length: 661
• Identity: 154/661 - (23%)
• Similarity: 282/661 - (42%)
• Gaps: 93/661 - (14%)

  Fly    51 TIDPCENFYEFSCGGWKKADLVPEQARNTSFLNAIQHKIDEQIQGFLQNATKRELEDLGVNGTTS 115
            ::|||::||:..||.:.:...: .|.|..:..:.:...|.|.:   |:|.|          .|:.
 Worm    96 SVDPCQDFYQHFCGKFYEHSAI-GQGRMATKRSTLSKLIREFL---LKNKT----------STSK 146

  Fly   116 AEIKAKQFYASCVEMK--ANL-SLGYQYFMEHDGDRLKERNA----TYDWMYINFMSKYDIYPLL 173
            :|...||.||.|.|::  ::| |:..|..::...| :|:..|    ..||    ..||:::..:|
 Worm   147 SENTMKQVYAKCRELQKISDLNSIPPQALLDIFSD-IKKIGAWPVLDKDW----DGSKFNLNEML 206

  Fly   174 ALKV----------HYSTSSRKFDILLTLPSKVLAGFSEEQLKNMTR------EFGLDSS-AEKV 221
            ...|          |:...:|.: :|:..|.|  .|..:..|:.:.:      |..:|.. :|.:
 Worm   207 RQLVNLGETHLGFFHFDFIARPY-VLIKPPLK--QGVQKSVLEKVVKMILEANEIKMDQGFSEDL 268

  Fly   222 KQFVE-----NFNNLTQFERNLVSLAKSRNETEQLNFKEFLVKHKHDRLNWTRFFELAFNGSQES 281
            .::.|     ..:.|.:..|::|.|..   :..::||:. |:.....|....||....|......
 Worm   269 DEYFELSNRIKIDKLPRTSRSIVGLLP---DVRRINFRG-LILEMMPRSKMNRFLGTLFQKVVTY 329

  Fly   282 HWPVLNQLDNINDLVFFLEQTNLETLKGYI---KMRELVKFYGLWKTQTKTGGVQSE---CRSLS 340
            |.|:..:.:..|.|...:..|:...|..|:   .:...:||.        |.|::|:   |..:.
 Worm   330 HHPLFVRDNETNHLDTIIRSTSNRALANYLIFNFIHSSIKFL--------TFGLKSDRERCEKIV 386

  Fly   341 ETYFNYALLPWFIGKVFDKERRADILSVAKDIKDTFYDLLDHHTWLDEDTRSQAKTKLASMDILV 405
            ........|..|:....||..|.::..:.:.:|:...:::..........:.:...|:.::..::
 Worm   387 VQELPRPSLRVFMRNCVDKGNREEVAKLTETVKENVLEMIRESDSFTPSVKKRVLKKVEAIGAII 451

  Fly   406 GYTDDLQHREVIDGVYSDINMTGNWFENLCILEGSRARIRLRSVDKAL---IPLLMPTRT--VNA 465
            ||.|.......:|..|.  |:|.:..::...:.....::||:...:.|   .||....:.  |||
 Worm   452 GYPDHFDPPGTLDKEYE--NLTLDASDSYYKMSQKLHQLRLQHQMEFLAGQTPLSPSDQVLEVNA 514

  Fly   466 YYADFLNLAFITIGMAQWPFYHIDFPDVLKYAGVGNIIGHEMAHGFDSYCYQYNYDGKKTNWWSS 530
            :|....|...:.......||:...:|:.:.....|.:||||..|..|....      ::..|:.:
 Worm   515 HYDSKDNALTVLAPFLDDPFFDSTYPEYVNLIFTGFLIGHEFGHSIDPKIL------RRDGWYKT 573

  Fly   531 ASLRNFKERYRCLESQYNKF--ILMGVQTNGSLTSGDNIADNVGTRMAYYAFKRKTGDKAWLEKP 593
            ..:..:.:|.:||..||:.:  ...|.|.||:...|:.:.|.||..:.:.|||     |..|.|.
 Worm   574 EDMTEYGKRAQCLIDQYDNYDDPDHGKQMNGTYCIGEIVGDWVGRDVTWRAFK-----KMDLSKM 633

  Fly   594 LRGVNFNNK---QLFFVKFAQTWCNGKDNGDKLRRLKTDVHAYDEFRVQGTLSNMPEFSEAFNCK 655
            .:.:.|.:|   ||:|...:..:| |..:...|.:|.:|.|..:.|||.|..||||:|::||||.
 Worm   634 QKLIGFEDKNLDQLYFRIQSLFFC-GPRSMKSLEQLLSDPHPTEVFRVNGIYSNMPQFAKAFNCP 697

  Fly   656 LGTEMNPLKKC 666
            :|:.|||.|||
 Worm   698 IGSPMNPEKKC 708

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl7	NP_001285879.1	PepO	43..669	CDD:226118	154/661 (23%)
		M13	52..666	CDD:189000	152/658 (23%)
nep-10	NP_494532.2	M13	97..709	CDD:189000	154/660 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6404
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.870