Protein Alignment Nepl7 and nep-9

DIOPT Version :9

• Sequence 1: NP_001285879.1
• Gene: Nepl7 / 34671
• FlyBaseID: FBgn0032442
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_494531.2
• Gene: nep-9 / 173683
• WormBaseID: WBGene00017554
• Length: 700
• Species: Caenorhabditis elegans
• Alignment Length: 676
• Identity: 139/676 - (20%)
• Similarity: 270/676 - (39%)
• Gaps: 129/676 - (19%)

  Fly    55 CENFYEFSCGGWKKADLVPEQARNTSFLNAIQHKIDEQIQGFLQNATKRELEDLGVNGTTSAEIK 119
            ||:||:.:|..:|....: ::.|:.....|    :::.::||||....        ..|:.:|..
 Worm    87 CEDFYKATCENYKDHQAL-DRHRDCKKRKA----VNKLVRGFLQRDES--------TFTSESESA 138

  Fly   120 AKQFYASCVEMKANLSLGYQYFMEHDGDRLKERNATYDWMYINFMSKYDIYPLLALKVHYSTSSR 184
            .|..:..|.|:..|.|    |.     |..|:            :.|...:|:|    .::....
 Worm   139 IKLIFGKCDELSRNTS----YL-----DIFKD------------IKKIGSWPVL----EHNWKDS 178

  Fly   185 KFDI------LLTLPSKVLAGFSEEQLKNMTREFGLDSSAEKVKQFVENFNNLTQFERNLVSLAK 243
            .|::      |:.|.|.....|..|..|.....|.:..|:::.:       |:.|.|:.::.:.|
 Worm   179 MFNLDDVIAKLVKLGSTDFGLFKLELRKLAFGHFAVFVSSKQEQ-------NIHQLEKTILGILK 236

  Fly   244 SRN-ETEQLNFKEFLVKHKHDRLNWTRFFE-------LAFNGS----------------QESHWP 284
            :.. :.::....:.|..:...:.:...|::       ..:.||                :.:...
 Worm   237 ANGIQQDRKELSDDLKDYSDFKNHLKEFYQEETYIEYRLYAGSIVENLGISSLTTQMALKSTGLD 301

  Fly   285 VLNQLDN----INDLVFFLEQTNLETLKGYIKMRELVKFYGLWKTQTKTGGVQSECRSLSETYFN 345
            |.|.::.    .|..:||.|:.||..:......|.|..|.........|..:.:..::..||..:
 Worm   302 VFNHVNQRTLITNSSLFFGEENNLGMIIQKTPKRTLANFLIFHFIDVMTTDLANATKACKETLID 366

  Fly   346 YALLP----WFIGKVF-DKERRADILSVAKDIKDTFYDLLDH-------HTWLDEDTRSQAKTKL 398
              |||    ..:.:.| :::.:.|::.:|:|:|....:::|:       |...|.:.:.:...|:
 Worm   367 --LLPRASIQVLSRNFVNEDAQDDMVKMAQDLKTKITEMIDNSPFFTKFHLVFDAEEQKKLIQKV 429

  Fly   399 ASMDILVGYTDDLQHREVIDGVYSDINMTGNWFENLCILEGSRARIRLRSVDKALIPLLMPTRT- 462
            .::.|:..|.     :||:|..:..:|:|.:  :::........|:|...:.:.|...|.||.|
 Worm   430 KAIGIVTEYP-----QEVLDRDFERLNLTPS--DSIYRTIQKLRRLRSEQLIEHLGGDLDPTDTR 487

  Fly   463 --VNAYYADFLNLAFITIGMAQWPFYHIDFPDVLKYAGVGNIIGHEMAHGFDSYCYQYNYDGKKT 525
              .:|:|....|...|...:...|::...:|:.:....:|.|:|.|:....||...:.:..|:..
 Worm   488 VWGSAHYDQTTNNLTIFAPIIDGPYFDTSYPNYVNQFLMGFILGRELGRSLDSVRIRKDEKGQTE 552

  Fly   526 NWWSSASLRNFKERYRCLESQYNKFI------LMGV-QTNGSLTSGDNIADNVGTRMAYYAF-KR 582
            ||....||:.|.|..:|...:|:|..      ..|: |..|.....:..||.:|...::.|| |.
 Worm   553 NWLKPESLKRFDEHLKCWAEKYDKSADPLKSESKGIRQIEGRYIQNEMFADFIGHEASWRAFMKL 617

  Fly   583 KTGDKAWLEK----PLRGVNFNNKQLFFVK---FAQTWCNGKDNGDKLRRLKTDVHAYDEFRVQG 640
            ...::..||.    .||.:.||.:.|:|.:   .:..|.:.:::           |.:..|||.|
 Worm   618 DVKNEEVLETFKVIKLRRMFFNVQALYFCRPPSGSTDWLSYQEH-----------HQHYSFRVNG 671

  Fly   641 TLSNMPEFSEAFNCKLGTEMNPLKKC 666
            ...|||:|:.||.|....:|||..||
 Worm   672 AFKNMPQFALAFECASDDDMNPQNKC 697

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl7	NP_001285879.1	PepO	43..669	CDD:226118	139/676 (21%)
		M13	52..666	CDD:189000	137/674 (20%)
nep-9	NP_494531.2	M13	87..698	CDD:189000	139/676 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910