Protein Alignment Nepl7 and phex

DIOPT Version :10

• Sequence 1: NP_609577.2
• Gene: Nepl7 / 34671
• FlyBaseID: FBgn0032442
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: XP_004911718.1
• Gene: phex / 100496470
• XenbaseID: XB-GENE-1012247
• Length: 750
• Species: Xenopus tropicalis
• Alignment Length: 765
• Identity: 187/765 - (24%)
• Similarity: 324/765 - (42%)
• Gaps: 154/765 - (20%)

  Fly     9 LISLTLIGRVLAN---DLFSLPPATNHREEMLEDYGRFLLSTMNRTIDPCENFYEFSCGGWKKAD 70
            |:.|.|:.:.|.:   |.:.|.|      |.:| ....:.|.||.::|||::|::::||||.:.:
 Frog    36 LVLLLLVSKGLISFQKDEYCLTP------ECIE-AAASIRSKMNLSVDPCDDFFQYACGGWIEEN 93

  Fly    71 LVPEQARNTSFLNAIQHKIDEQIQGFLQNATKRELEDLGVNGTTSAEIKAKQFYASCV------- 128
            .:|:...|......::..:|.:::..|:....:..:...:.       |.|.||.||:
 Frog    94 PIPDDMSNYGIYPWLRTNVDLKLKALLEKPISKRRDSEAIQ-------KVKTFYISCMNETQIEE 151

  Fly   129 -EMKANLSLGYQYFMEHDGDRLKERNATYDWMYINFMS-------KYDIYPLLA-LKVHYSTSSR 184
             ::|..|.:            ||:.:..:..:..|..|       |:.....:| |:..||||.
 Frog   152 DDIKPILKI------------LKQPSLRWPVLESNIGSDGKWSERKFSFLQTVADLRRLYSTSV- 203

  Fly   185 KFDILLTLPSKVLAGF----SEEQLKNMTREFGLDSS--AEKVKQFVENF---------NNLTQF 234
            ...:.:.:..||...|    .:..|..::.|..||:|  |:|.:..:..|         .|.|:.
 Frog   204 FLRVYVAIDDKVSNNFILKLDQASLSLLSHEDYLDNSTIAKKYRDALLEFMVDVAVLLGANKTRA 268

  Fly   235 ERNLVSLAK-----------SRNETEQLNFKEFLVKHKH---DRLNWTRFFE--LAFNGSQESHW 283
            |.::.:|.:           ..|.|.::.:.:..:....   .:.:|..:.:  :.||     .:
 Frog   269 ETDMKALIELETKLAQITVPQENRTSEMMYNKMNISELSAMIPQFDWLSYLKNIIDFN-----IY 328

  Fly   284 PVLNQLD-----------NINDLVFFLEQTNLETLKGYIKMRELVKFYGLWKTQTKTGGVQSECR 337
            |.|..:|           :..||...:|.....||..|:          :|:.      |.|...
 Frog   329 PELKNIDLSENVIVRVPQHFKDLFNIIESEEKRTLANYL----------IWRL------VYSRIP 377

  Fly   338 SLSETY------------------------FNYA--LLPWFIGKVF----DKERRADILSVAKD- 371
            :||..:                        .||.  .:|:.:||:|    .:|.:.|::....|
 Frog   378 NLSRRFQYRQLEFARILLGTNSLAGRWDRCVNYVENSIPYPVGKLFVDAHFQEDKKDMMEELVDG 442

  Fly   372 IKDTFYDLLD-HHTWLDEDTRSQAKTKLASMDILVGY-----TDDLQHREVIDGVYSDINMTGNW 430
            |:..|.|:|: .:.|:|.:|:.:||.|..::...|||     .|...:.::....:|:.:..||.
 Frog   443 IRWAFIDMLEKENDWMDAETKIKAKQKAVTVMAKVGYPEFLFNDTYLNEDIKMLKFSESDYFGNV 507

  Fly   431 FENLCILEGSRARIRLRSVDKALIPLLMPTRTVNAYYADFLNLAFITIGMAQWPFY-HIDFPDVL 494
            .:.|..:..|......|:|.|... ...|| ||||:|:...|......|..|.||: .:.:|..|
 Frog   508 LQTLHFISQSDFYWLRRNVPKKEW-FTNPT-TVNAFYSASTNQIRFPAGELQKPFFWGVQYPRSL 570

  Fly   495 KYAGVGNIIGHEMAHGFDSYCYQYNYDGKKTNWWSSASLRNFKERYRCLESQYNKFI--LMGVQT 557
            .|..:|.|:|||..||||:...:|:.:|...:||:|.|...||.:..|:..|||.:.  ..|:..
 Frog   571 SYGAIGVIVGHEFTHGFDNNGRKYDKEGNLFSWWTSESEERFKNKTLCMVEQYNNYYWKQAGLHV 635

  Fly   558 NGSLTSGDNIADNVGTRMAYYAFKRKTGD--KAWLEKPLRGVNFNNKQLFFVKFAQTWCNGKDNG 620
            .|..|..:|||||.|.|.::.|:::...|  |...|..|.|::.||.||||:.:|...||.....
 Frog   636 KGMKTLSENIADNGGIRESFRAYRKWIEDLRKGKEEMLLPGLDLNNNQLFFISYAHVRCNSFRIE 700

  Fly   621 DKLRRLKTDVHAYDEFRVQGTLSNMPEFSEAFNCKLGTEMN-PLKKCVVW 669
            ....::...||:..:|||.|.:||..||.:||:|...::|| ....|.||
 Frog   701 SARDQIMNGVHSPPQFRVIGAMSNFEEFHKAFSCPKDSKMNRGANSCRVW 750

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl7	NP_609577.2	M13	52..666	CDD:341056	172/714 (24%)
phex	XP_004911718.1	M13	75..741	CDD:341056	170/708 (24%)