Protein Alignment Nepl7 and ece2

DIOPT Version :10

• Sequence 1: NP_609577.2
• Gene: Nepl7 / 34671
• FlyBaseID: FBgn0032442
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: XP_002935189.1
• Gene: ece2 / 100488407
• XenbaseID: XB-GENE-1011916
• Length: 766
• Species: Xenopus tropicalis
• Alignment Length: 768
• Identity: 219/768 - (28%)
• Similarity: 341/768 - (44%)
• Gaps: 163/768 - (21%)

  Fly     1 MVNALWATLISLTLIGRVLANDLFSLPPATNH---REEMLEDYGRFLLSTMNRTIDPCENFYEFS 62
            ::.||.|.| .:.|:|.::|..:..:...:..   .|..:...|| :|.:::|.||||::||::|
 Frog    63 LLGALSAVL-GVLLLGSLIALGVQQMTDRSRSLCLSEACVSVAGR-ILDSLDRGIDPCQDFYQYS 125

  Fly    63 CGGWKKADLVPEQARNTSFLNAIQHKIDEQIQGFLQNATKRELEDLGVNGTTSAEIKAKQFYASC 127
            ||||.:.:.:|:.....:..|:|..:....::..|:|||        .|.::.||:|.::||.||
 Frog   126 CGGWMRRNPLPDGRSRWNTFNSIWDQNQAILKHILENAT--------FNSSSEAEMKTQRFYLSC 182

  Fly   128 VEMKANLSLGYQYFMEHDGDRLKER------------NATYDWMYINFMS-------KYDIYPLL 173
            ::             |...:.|:::            |.:.:|...||||       .|...|..
 Frog   183 LK-------------EQRIEELRQKPLTDLIEKIGGWNISGNWRGENFMSVLKTVSGTYRATPFF 234

  Fly   174 ALKVHYSTSSRKFDIL------LTLPS-----------KVLAGFSEEQLKNMTREFG-----LDS 216
            ::.|...:.|...:|:      |.|||           |||..:. :.:.::....|     :|.
 Frog   235 SVFVSADSKSSNSNIIQVDQSGLFLPSRDYYLNKTANGKVLDAYL-QYMVSVGELLGGSPGSVDM 298

  Fly   217 SAEKVKQFVENFNNLT--QFER-------------NLVSLAKSRNETEQLNF------------- 253
            ...::.:|.....|||  |.||             .|.|||.:.:..:.|.|
 Frog   299 QMTQILEFETLLANLTVPQDERRDEEKIYNRMTISELQSLAPAFDWMDYLTFALSPLDLNDTEPV 363

  Fly   254 ----KEFLVKHKHDRLNWTRFFELAFNGSQESHWPVLNQLDNINDLVFFLEQTNLETLKGYIKMR 314
                ||:|          .:..||..|..     |:|  |:|.  ||:.|.|....:|....:..
 Frog   364 VVYGKEYL----------QQVSELVNNTD-----PML--LNNY--LVWNLVQKMSSSLDSRFEKA 409

  Fly   315 E---LVKFYGL-------WKTQTKTGGVQSECRSLSETYFNYALLPWFIGKVFDKERRADILSVA 369
            :   |...||.       |:|          |.|.::....:||...|:...|||..:.....:.
 Frog   410 QDKLLESLYGAKKSCTPRWQT----------CLSNTDDTLGFALGSLFVKSTFDKNSKNIAEQMI 464

  Fly   370 KDIKDTFYDLLDHHTWLDEDTRSQAKTKLASMDILVGYTDDLQHREVIDGVYSDINMTGN-WFEN 433
            .:|:|.|...|...||:||.||..||.|..::..::|:.|.:...:.:|.||....::.: :|:|
 Frog   465 SEIRDAFELTLGGLTWMDEKTRRAAKEKADAIYDMIGFPDFILDTKELDEVYDGFEVSEDAFFQN 529

  Fly   434 LCILEGSRARIRLRSVDK-------ALIPLLMPTRTVNAYYADFLNLAFITIGMAQWPFYHIDFP 491
            :.......|::....:.|       ::.|     :||||||....|......|:.|.|||....|
 Frog   530 MLNFYNFSAKLMAEQLRKPPNREQWSMTP-----QTVNAYYLPNKNEIVFPAGILQAPFYAPTHP 589

  Fly   492 DVLKYAGVGNIIGHEMAHGFDSYCYQYNYDGKKTNWWSSASLRNFKERYRCLESQYNKFILMGVQ 556
            ..|.:.|:|.::|||:.|.||....:|:.||....||.::||..||.|..|:.:|||.:.:.|.:
 Frog   590 KALNFGGIGVVMGHELTHAFDDQGREYDEDGNLRPWWQNSSLEAFKNRTECMVNQYNSYTVNGER 654

  Fly   557 TNGSLTSGDNIADNVGTRMAYYAFKRKTGDKAWL-----EKPLRGVNFNNKQLFFVKFAQTWCNG 616
            .||..|.|:|||||.|.:.||:|:      |:||     ||.|.||...|.|||||.|||.||:.
 Frog   655 VNGRQTLGENIADNGGLKAAYHAY------KSWLVKHGEEKQLPGVGLTNNQLFFVGFAQVWCSV 713

  Fly   617 KDNGDKLRRLKTDVHAYDEFRVQGTLSNMPEFSEAFNCKLGTEMNPLKKCVVW 669
            :........|.||.|:..:|||.|||||..:|:|.|||..||.|||.|.|.||
 Frog   714 RTPESSHEGLVTDPHSPAKFRVIGTLSNSKDFAEHFNCPKGTPMNPGKHCDVW 766

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl7	NP_609577.2	M13	52..666	CDD:341056	204/709 (29%)
ece2	XP_002935189.1	M13	115..763	CDD:341056	204/709 (29%)