Protein Alignment Nepl7 and ecel1

DIOPT Version :10

• Sequence 1: NP_609577.2
• Gene: Nepl7 / 34671
• FlyBaseID: FBgn0032442
• Length: 669
• Species: Drosophila melanogaster
• Sequence 2: NP_001429584.1
• Gene: ecel1 / 100332538
• ZFINID: ZDB-GENE-130530-692
• Length: 808
• Species: Danio rerio
• Alignment Length: 752
• Identity: 203/752 - (26%)
• Similarity: 335/752 - (44%)
• Gaps: 141/752 - (18%)

  Fly    14 LIGRVLANDLFSLPPATNH-------REEMLEDYGRFLLSTMNRTIDPCENFYEFSCGGWKKADL 71
            ::|.:||....||....:.       |..:|. ..||:...::.::.||.:||.|:||||.:...
Zfish   102 ILGCMLALKFLSLESQDSQCRQDCVKRRSLLR-AARFVQGNIDPSVQPCHDFYSFACGGWLRRHG 165

  Fly    72 VPEQARNTSFLNAIQHKIDEQIQGFLQ-NATKRELEDLGVNGTTSAEIKAKQFYASCVEMKANLS 135
            :||...:...:.||..:..:::|..|| ...:||||        |||.|.|:||.||:.:|....
Zfish   166 IPEDKLSYGIITAIGEQNQDKLQRLLQAPVQRRELE--------SAERKVKEFYRSCINIKEIDR 222

  Fly   136 LGYQYFMEHDGDRLKERNATYDW-------------------------MYINFMSKY--DIYPLL 173
            ||       .|...:..::...|                         |.......|  .::..|
Zfish   223 LG-------AGPMTEVIDSCGGWDLSGAPPGGAGWDSGSAPIRPDFNEMLYKTQGVYSTSVFFSL 280

  Fly   174 ALKVHYSTSSRKFDIL----LTLPS------------KVLAGFSE--EQLKNMTREFGLDSSAEK 220
            .:.|....|||....:    ||||.            |:||.:..  |:|.:|   .|..::..|
Zfish   281 TVSVDDKNSSRNAIRIDQEGLTLPERTLYLGQDEDSVKILASYKALMERLLSM---LGAHNATLK 342

  Fly   221 VKQFVENFNNLTQFERNLVSLAKSRNETEQLNFKEFLVKHKHDRL------------NWTRFFEL 273
            .::.::       .|..|.::..|..|.::.:     :...::|:            :|.|..:.
Zfish   343 SREILD-------LETKLANITVSEYEDQRKD-----ISSMYNRITLKQLQKMAPSFHWKRLLDR 395

  Fly   274 AFNG--SQESHWPVL--NQLDNINDLVFFLEQTNLETLKGYIKMRELVKFYGLWKTQTKT----- 329
            .||.  |:|....||  :.:..::|::   :.|:...|..|:..|.:........|..::
Zfish   396 IFNDNFSEEEEIVVLATDYMQTVSDII---KTTSKRVLHNYMLWRMVAALSEHLSTAFRSTIHEF 457

  Fly   330 ----GGVQSE------CRSLSETYFNYALLPWFIGKVFDKERRADILSVAKDIKDTFYDLLDHHT 384
                .|.:.:      |.:.:..:|..||...|:.:.|....||.:..:.:|||.:....|....
Zfish   458 SREIDGTEQQLDLERLCLTQANKHFGMALGALFVQQHFSSSSRAKVQELVEDIKHSLDVRLQELD 522

  Fly   385 WLDEDTRSQAKTKLASMDILVGYTDDLQHREVIDGVYS-DINMTGNWFENLCILEGSRARIRL-- 446
            |:||:|:..|:.||..|.::.||.|.|...|:||..|: |:| ...:|:|  ||...:..|:|
Zfish   523 WMDEETKDAARGKLQHMMVMTGYPDFLLKPELIDEEYAFDVN-EKTYFKN--ILNSIKYNIKLSI 584

  Fly   447 ----RSVDKALIPLLMPTRTVNAYYADFLNLAFITIGMAQWPFYHIDFPDVLKYAGVGNIIGHEM 507
                :.|||.  ..|:|.:.:||||....|......|:.|...|..:||..|.|.|:|.|||||:
Zfish   585 KKIHKEVDKT--TWLLPPQALNAYYLPNKNQMVFPAGILQPTLYDPEFPQSLNYGGIGAIIGHEL 647

  Fly   508 AHGFDSYCYQYNYDGKKTNWWSSASLRNFKERYRCLESQYNKFILMGVQTNGSLTSGDNIADNVG 572
            .||:|.:..||:..|....||:..|.|.|:::..|:...|:.|.:...:.||.||.|:||||..|
Zfish   648 THGYDDWGGQYDRYGNLKQWWTEESYRKFQKKTECIVKLYDNFTVYNQRVNGRLTLGENIADLGG 712

  Fly   573 TRMAYYAFKRKTGDKAWL-----EKPLRGVNFNNKQLFFVKFAQTWCNGKDNGDKLRRLKTDVHA 632
            .:::|:|:::      |:     |:||.|:...::||||:.|||.||..:.:.....:|.||.||
Zfish   713 LKLSYHAYQK------WVREHGPERPLPGLKHTHEQLFFIAFAQNWCMKRRSQSIYLQLLTDKHA 771

  Fly   633 YDEFRVQGTLSNMPEFSEAFNCKLGTEMNPLKKCVVW 669
            .:.:||.|::|...||...|:|..|:.|||:.||.||
Zfish   772 PEHYRVIGSVSQFEEFGRVFHCPRGSPMNPVNKCSVW 808

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl7	NP_609577.2	M13	52..666	CDD:341056	190/702 (27%)
ecel1	NP_001429584.1	None