Protein Alignment nub and POU6F1

DIOPT Version :9

• Sequence 1: NP_001097153.1
• Gene: nub / 34669
• FlyBaseID: FBgn0085424
• Length: 961
• Species: Drosophila melanogaster
• Sequence 2: XP_016874997.1
• Gene: POU6F1 / 5463
• HGNCID: 9224
• Length: 613
• Species: Homo sapiens
• Alignment Length: 539
• Identity: 143/539 - (26%)
• Similarity: 213/539 - (39%)
• Gaps: 140/539 - (25%)

  Fly   505 TQSPSNSVKSATASPVPVISVPS----------------PVPPMISPVLAPSGCGS--------- 544
            :|:||....|.|.:|:.|.:.|.                |...:..|:|.|.....
Human   100 SQAPSQPQASQTLTPLAVQAAPQVLTQENLATVLTGVMVPAGAVTQPLLIPISIAGQVAGQQGLA 164

  Fly   545 --TTPNSMAAAAAAAAAVASTMGSGISPL----------LALPGMSSPQAQLAAAGLGMNNPLLT 597
              |.|.:..||.....|.:.|.|....||          .|||......|.:.|:......|
Human   165 VWTIPTATVAALPGLTAASPTGGVFKPPLAGLQAAAVLNTALPAPVQAAAPVQASSTAQPRP--- 226

  Fly   598 GSLSPQDFAQFHQLLQQRQVALTQQ-------------------------FNSYMELLRSGSLGL 637
             ...||...|...|||.....|.|.                         |.....::.:.|||
Human   227 -PAQPQTLFQTQPLLQTTPAILPQPTAATAAAPTPKPVDTPPQITVQPAGFAFSPGIISAASLG- 289

  Fly   638 AQDD--------PALTAQV-----AAAQFLMQSQLQAL-------SQASQQLQALQKQQQRQVDE 682
            .|..        |.:|:.:     .::|.|..:|.|.:       :.||....|..:..|.|...
Human   290 GQTQILGSLTTAPVITSAIPSMPGISSQILTNAQGQVIGTLPWVVNSASVAAPAPAQSLQVQAVT 354

  Fly   683 PLQLNHKMTQQPRSSTPHSIRSPIAIRSPASSPQQLHHHHHHPLQITP----------------- 730
            |..|.:...|...:.....:..|:|:|.| |:|:........|:|.||
Human   355 PQLLLNAQGQVIATLASSPLPPPVAVRKP-STPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAK 418

  Fly   731 PSSAASLKLSGMLTPSTPTSGTQMSQGTTTPQPKTVASAAAARAAGEPS-PEETTDLEELEQFAK 794
            ||::|.:.::...||:       :||..::.:|.|            || .|:..:|||:.:|||
Human   419 PSASAPIPITCSETPT-------VSQLVSSLEPHT------------PSLDEDGINLEEIREFAK 464

  Fly   795 TFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLQKWLDDADRTIQ 859
            .||.||:.||.||..||.|:....|..:||:.|.|||.|:::.|:..||||:|:|||::|:...|
Human   465 NFKIRRLSLGLTQTQVGQALTATEGPAYSQSAICRFEKLDITPKSAQKLKPVLEKWLNEAELRNQ 529

  Fly   860 ATGGVFDPAALQATVSTPEIIG----RRRKKRTSIETTIRGALEKAFLANQKPTSEEITQLADRL 920
                       :...:..|.:|    ::||:|||.......||...|..|..||.:|||::|..|
Human   530 -----------EGQQNLMEFVGGEPSKKRKRRTSFTPQAIEALNAYFEKNPLPTGQEITEIAKEL 583

  Fly   921 SMEKEVVRVWFCNRRQKEK 939
            :.::||||||||||||..|
Human   584 NYDREVVRVWFCNRRQTLK 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nub	NP_001097153.1	DUF4472	315..>399	CDD:291409
		POU	791..855	CDD:197673	31/63 (49%)
		Homeobox	886..939	CDD:278475	26/52 (50%)
POU6F1	XP_016874997.1	Atrophin-1	<41..407	CDD:331285	64/312 (21%)
		POU	451..525	CDD:197673	35/73 (48%)
		Homeobox	549..602	CDD:306543	26/52 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910