Protein Alignment nub and POU4F1

DIOPT Version :9

• Sequence 1: NP_001097153.1
• Gene: nub / 34669
• FlyBaseID: FBgn0085424
• Length: 961
• Species: Drosophila melanogaster
• Sequence 2: NP_006228.3
• Gene: POU4F1 / 5457
• HGNCID: 9218
• Length: 419
• Species: Homo sapiens
• Alignment Length: 443
• Identity: 126/443 - (28%)
• Similarity: 180/443 - (40%)
• Gaps: 137/443 - (30%)

  Fly   601 SPQDFAQFHQLLQQRQVALTQQFNSYMELLRSGSLGLAQDDPALTAQVAAAQFLMQSQLQALSQA 665
            |.|.....|..|.:.:.   ...:|..|.:|...|    ..|.|.:.:.|:   :...|.|.::|
Human     6 SKQPHFAMHPTLPEHKY---PSLHSSSEAIRRACL----PTPPLQSNLFAS---LDETLLARAEA 60

  Fly   666 SQQLQALQKQQQRQVDEPLQLNHKMTQQPRSSTPHSIRSPIAIRSPASSPQQLHHHHHHPLQITP 730
            ...:.....|.:....:|....|.|...|.:||             ::.|...||||||..|...
Human    61 LAAVDIAVSQGKSHPFKPDATYHTMNSVPCTST-------------STVPLAHHHHHHHHHQALE 112

  Fly   731 PS------SAASLKL-------------------------------------------------- 739
            |.      |:.||.|
Human   113 PGDLLDHISSPSLALMAGAGGAGAAAGGGGAHDGPGGGGGPGGGGGPGGGPGGGGGGGPGGGGGG 177

  Fly   740 --SGMLTPST--------------PTSGTQMSQGTTTPQPKTV--------ASAAAARAAGEPSP 780
              .|:|..|.              |.:...|:..:..|.|..|        |:||||.|||:.:.
Human   178 PGGGLLGGSAHPHPHMHSLGHLSHPAAAAAMNMPSGLPHPGLVAAAAHHGAAAAAAAAAAGQVAA 242

  Fly   781 -----------------EETTDLEELEQFAKTFKQRRIKLGFTQGDVGLAMG--KLYG-NDFSQT 825
                             :..||..|||.||:.|||||||||.||.|||.|:.  |:.| ...||:
Human   243 ASAAAAVVGAAGLASICDSDTDPRELEAFAERFKQRRIKLGVTQADVGSALANLKIPGVGSLSQS 307

  Fly   826 TISRFEALNLSFKNMCKLKPLLQKWLDDADRTIQATGGVFDPAALQATVSTPEII--GRRRKKRT 888
            ||.|||:|.||..||..|||:||.||::|:            .|.:..::.||:.  |.:::|||
Human   308 TICRFESLTLSHNNMIALKPILQAWLEEAE------------GAQREKMNKPELFNGGEKKRKRT 360

  Fly   889 SIETTIRGALEKAFLANQKPTSEEITQLADRLSMEKEVVRVWFCNRRQKEKRI 941
            ||....:.:||..|....:|:||:|..:|::|.::|.||||||||:|||:||:
Human   361 SIAAPEKRSLEAYFAVQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQKQKRM 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nub	NP_001097153.1	DUF4472	315..>399	CDD:291409
		POU	791..855	CDD:197673	38/66 (58%)
		Homeobox	886..939	CDD:278475	26/52 (50%)
POU4F1	NP_006228.3	POU-IV box	57..66		1/8 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	94..117		9/22 (41%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	131..197		3/65 (5%)
		POU	260..337	CDD:197673	43/76 (57%)
		Homeobox	358..411	CDD:278475	26/52 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3802
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810